Minn. R. agency 144, ch. 4717, HEALTH RISK VALUES, pt. 4717.8150

Current through Register Vol. 49, No. 20, November 12, 2024
Part 4717.8150 - TABLE OF SUBCHRONIC HRVS

The heading for each item contains the chemical name and, in parenthesis, the CAS RN. Each item lists the subchronic HRV, the equation used to develop the subchronic HRV, and the variables necessary for the equation. The equations used to develop the subchronic HRV are designated as follows: "A" means calculating the NOAEL[HEC] or LOAEL[HEC] or BMC[HEC] under part 4717.8300, subpart 3, and applying the general equation under part 4717.8300, subpart 2; "B" means calculating the NOAEL[HEC] or LOAEL[HEC] or BMC[HEC] under part 4717.8300, subpart 4, and applying the general equation under part 4717.8300, subpart 2; "C" means calculating the NOAEL[HEC] or LOAEL[HEC] or BMC[HEC] under part 4717.8300, subpart 5, and applying the general equation under part 4717.8300, subpart 2; and "D" means calculating the NOAEL[HEC] or LOAEL[HEC] or BMC [HEC] under part 4717.8300, subpart 6, and applying the general equation under part 4717.8300, subpart 2. The endpoint of concern is listed for use in determining a hazard index under part 4717.8600.

TABLE OF SUBCHRONIC HRVs

A. Acrolein (107-02-8)

Subchronic HRV ( µg/m3)0.2
Endpoint of concernUpper respiratory system
EquationC
LOAEL[HEC] (mg/m3)2E-2
Uncertainty factor100

B. Acrylic acid (79-10-7)

Subchronic HRV ( µg/m3)3
Endpoint of concernUpper respiratory system
EquationC
LOAEL[HEC] (mg/m3)3.3E-1
Uncertainty factor100

C. Allyl chloride (107-05-1)

Subchronic HRV ( µg/m3)10
Endpoint of concernNervous system
EquationD
NOAEL[HEC] (mg/m3)3.6
Uncertainty factor300

D. Arsine (7784-42-1)

Subchronic HRV ( µg/m3)0.1
Endpoint of concernHematologic system
EquationD
NOAEL[HEC] (mg/m3)1.4E-2
Uncertainty factor100

E. Chlordane (12789-03-6)

Subchronic HRV ( µg/m3)7
Endpoint of concernHepatic system
EquationB
NOAEL[HEC] (mg/m3)6.5E-1
Uncertainty factor100

F. Chlorine dioxide (10049-04-4)

Subchronic HRV ( µg/m3)0.6
Endpoint of concernLower respiratory system
EquationC
LOAEL[HEC] (mg/m3)6.4E-1
Uncertainty factor1,000

G. Chromic acid mists and dissolved Cr (VI) aerosols (18540-29-9)

Subchronic HRV ( µg/m3)0.02
Endpoint of concernUpper and lower respiratory system
EquationC
LOAEL[ADJ] (mg/m3)7.1E-4
Uncertainty factor30

H. Cr (VI) particulates (18540-29-9)

Subchronic HRV ( µg/m3)1
Endpoint of concernLower respiratory system
EquationA
BMC[HEC] (mg/m3)3.5E-2
Uncertainty factor30

I. Cumene (98-82-8)

Subchronic HRV ( µg/m3)4,000
Endpoint of concernRenal system and endocrine system
EquationD
NOAEL[HEC] (mg/m3)4.35E2
Uncertainty factor100

J. 1,2-Dibromo-3-chloropropane (96-12-8)

Subchronic HRV ( µg/m3)2
Endpoint of concernMale reproductive system
EquationD
NOAEL[HEC] (mg/m3)1.7E-1
Uncertainty factor100

K. 1,4-Dichlorobenzene (106-46-7)

Subchronic HRV ( µg/m3)800
Endpoint of concernHepatic system
EquationD
NOAEL[HEC] (mg/m3)7.5E1
Uncertainty factor100

L. 1,2-Dichloropropane (78-87-5)

Subchronic HRV ( µg/m3)10
Endpoint of concernUpper respiratory system
EquationC
LOAEL[HEC] (mg/m3)1.3
Uncertainty factor100

M. Dicyclopentadiene (77-73-6)

Subchronic HRV ( µg/m3)3
Endpoint of concernRenal system
EquationD
LOAEL[HEC] (mg/m3)9.6E-1
Uncertainty factor300

N. 2-Dimethylamino ethanol (101-01-0)

Subchronic HRV ( µg/m3)70
Endpoint of concernUpper respiratory system
EquationC
NOAEL[HEC] (mg/m3)1.96
Uncertainty factor30

O. Ethylene glycol monomethyl ether (EGME) or 2-methoxyethanol (109-86-4)

Subchronic HRV ( µg/m3)60
Endpoint of concernMale reproductive and hematologic systems
EquationD
NOAEL[HEC](mg/m3)1.7E1
Uncertainty factor300

P. Hydrogen sulfide (7783-06-4)

Subchronic HRV ( µg/m3)10
Endpoint of concernUpper respiratory system
EquationC
NOAEL[HEC] (mg/m3)1.01
Uncertainty factor100

Q. Phosphine (7803-51-2)

Subchronic HRV ( µg/m3)3
Endpoint of concernDecreased body weight
EquationD
NOAEL[HEC] (mg/m3)2.5E-1
Uncertainty factor100

R. Propylene glycol monomethyl ether (107-98-2)

Subchronic HRV ( µg/m3)20,000
Endpoint of concernNervous system
EquationD
NOAEL[HEC] (mg/m3)6.58E2
Uncertainty factor30

S. Triethylamine (121-44-8)

Subchronic HRV ( µg/m3)70
Endpoint of concernUpper respiratory system
EquationC
NOAEL[HEC] (mg/m3)1.95E1
Uncertainty factor300

Minn. R. agency 144, ch. 4717, HEALTH RISK VALUES, pt. 4717.8150

26 SR 1229; 26 SR 1395

Statutory Authority: MS s 144.12