Rule 20.
EQUATION FOR CARCINOGENS:
where, | ||
DCC | (Direct contact criterion) | = chemical-specific, ug/kg or ppb |
TR | (Target risk level) | = 10-5 |
AT | (Averaging time) | = 25,550 days (70 years x 365 days/year) |
CF | (Conversion factor) | = 1E+9 ug/kg |
SF | (Oral cancer slope factor) | = chemical-specific (mg/kg-day)-1 |
EFi | (Ingestion exposure frequency) | = 350 days/year |
IF | (Age-adjusted soil ingestion factor) | = 114 mg-year/kg-day* |
AEi | (Ingestion absorption efficiency) | = chemical-specific or default specified at R 299.20(3) |
EFd | (Dermal exposure frequency) | = 245 days/year |
DF | (Age-adjusted soil dermal factor) | = 353 mg-year/kg-day** |
AEd | (Dermal absorption efficiency) | = chemical-specific or default specified at R 299.20(3) |
EQUATIONS FOR NONCARCINOGENS:
where, | ||
DCC | (Direct contact criterion) | = chemical-specific (ug/kg or ppb) |
THQ | (Target hazard quotient) | = 1 |
RfD | (Oral reference dose) | = chemical-specific mg/kg-/day |
AT | (Averaging time) | = 10,950 days (30 years x 365 days/year) |
CF | (Conversion factor) | = 1E+9 ug/kg |
RSC | (Relative source contribution) | = 1 |
EFi | (Ingestion exposure frequency) | = 350 days/year |
IF | (Age-adjusted soil ingestion factor) | = 114 mg-year/kg-day* |
AEi | (Ingestion absorption efficiency) | = chemical-specific or default specified at R 299.20(3) |
EFd | (Dermal exposure frequency) | = 245 days/year |
DF | (Age-adjusted soil dermal factor) | = 353 mg-year/kg-day** |
AEd | (Dermal absorption efficiency) | = chemical-specific or default specified at R 299.20(3) |
and,
where, | ||
IRsoil/age 1-6 | (Soil ingestion rate) | = 200 mg/day |
EDage 1-6 | (Exposure duration) | = 6 years |
BWage 1-6 | (Body weight) | = 15 kg |
IRadult | (Soil ingestion rate) | = 100 mg/day |
EDadult | (Exposure duration) | = 24 years |
BWadult | (Body weight) | = 70 kg |
and,
where, | ||
SAage 1-6 | (Skin surface area) | = 2,670 cm2/dayevent |
EV | (Event frequency) | = 1 event/day |
AFage 1-6 | (Soil adherence factor) | = 0.2 mg/cm2 |
EDage 1-6 | (Exposure duration) | = 6 years |
BWage 1-6 | (Body weight) | = 15 kg |
SAadult | (Skin surface area) | = 5,800 cm2/dayevent |
AFadult | (Soil adherence factor) | = 0.07 mg/cm2 |
EDadult | (Exposure duration) | = 24 years |
BWadult | (Body weight) | = 70 kg |
EQUATION FOR CARCINOGENS:
where, | ||
DCC | (Direct contact criterion) | = chemical-specific, ug/kg or ppb |
TR | (Target risk level) | = 10-5 |
BW | (Body weight) | = 70 kg |
AT | (Averaging time) | = 25,550 days (70 years x 365 days/year) |
CF | (Conversion factor) | = 1E+9 ug/kg |
SF | (Oral cancer slope factor) | = chemical-specific (mg/kg-day)-1 |
ED | (Exposure duration) | = 21 years |
EFi | (Ingestion exposure frequency) | = 245 days/year |
IRs | (Soil ingestion rate) | = 100 mg/day (residential) |
AEi | (Ingestion absorption efficiency) | = chemical-specific or default specified at R 299.20(3) |
EFd | (Dermal exposure frequency) | = 160 days/year |
SA | (Skin surface area) | = 3,300 cm2/day event |
EV | (Event frequency) | = 1 event/day |
AF | (Soil adherence factor) | = 0.2 mg/cm2 (nonresidential) |
AEd | (Dermal absorption efficiency) | = chemical-specific or default specified at R 299.20(3) |
EQUATION FOR NONCARCINOGENS:
where, | ||
DCC | (Direct contact criterion) | = chemical-specific, ug/kg or ppb |
THQ | (Target hazard quotient) | = 1 |
RfD | (Oral reference dose) | = chemical-specific, mg/kg-/day |
BW | (Body weight) | = 70 kg |
AT | (Averaging time) | = 7,665 days (21 years x 365 days/year) |
CF | (Conversion factor) | = 1E+9 ug/kg |
RSC | (Relative source contribution) | = 1 |
ED | (Exposure duration) | = 21 years |
EFi | (Ingestion exposure frequency) | = 245 days/year |
IRs | (Soil ingestion rate) | = 100 mg/day |
AEi | (Ingestion absorption efficiency) | = chemical-specific or default specified at R 299.20(3) |
EFd | (Dermal exposure frequency) | = 160 days/year |
SA | (Skin surface area) | = 3,300 cm2/day event |
EV | (Event frequency) | = 1 event/day |
AF | (Soil adherence factor) | = 0.2 mg/cm2 (nonresidential) |
AEd | (Dermal absorption efficiency) | = chemical-specific or default specified at R 299.20(3) |
Mich. Admin. Code R. 299.20