Rule 10.
EQUATION FOR CARCINOGENIC EFFECTS:
where, | ||
DWC | (Drinking water criterion) | = chemical-specific (ug/L or ppb) |
TR | (Target risk level) | = 10-5 |
BW | (Body weight) | = 70 kg |
AT | (Averaging time in days) | = 25,550 days (70 years x 365 days/year) |
CF | (Conversion factor) | = 1000 ug/mg |
SF | (Oral cancer slope factor) | = chemical-specific (mg/kg-day)-1 |
EF | (Exposure frequency) | = 350 days/year (residential) |
= 245 days/year (nonresidential) | ||
ED | (Exposure duration) | = 30 years (residential) |
= 21 years (nonresidential) | ||
IRdw | (Drinking water ingestion rate) | = 2 liters/day (residential) |
= 1 liter/day (nonresidential) |
EQUATION FOR NONCARCINOGENS:
where, | ||
DWC | (Drinking water criterion) | = chemical-specific (ug/L or ppb) |
THQ | (Target hazard quotient) | = 1 |
RfD | (Oral reference dose) | = chemical-specific (mg/kg-day) |
BW | (Body weight) | = 70 kg |
= 10,950 days (30 years x 365 | ||
AT | (Averaging time) | days/year - residential) 7,665 days (21 years x 365 days/year - nonresidential) |
RSC | (Relative source contribution) | = chemical-specific or 0.2 if chemical-specific data are not available |
CF | (Conversion factor) | = 1000 ug/mg |
EF | (Exposure frequency) | = 350 days/year (residential) 245 days/year (nonresidential) |
ED | (Exposure duration) | = 30 years (residential) 21 years (nonresidential) |
IRdw | (Drinking water ingestion rate) | = 2 liters/day (residential) 1 liter/day (nonresidential) |
Mich. Admin. Code R. 299.10