* high number of prescribers in a short time period, as determined by the Office;
* high number of doses during a short time period, as determined by the Office;
* Days Supply of prescriptions for the same drug overlapping by more than a few days;
* inappropriate combinations of controlled substances, as determined by the Office;
* more than one method of payment within a short time period;
* more than one out of state prescriber for the same patient, during a short time period, as determined by the Office;
* more than one pharmacy on the same day;
* more than one pharmacy in different public health districts within one month; AND/OR
* dangerous levels of specific drugs, as determined by the Office.
Notification - When a patient surpasses the threshold levels established by the Office, the office shall notify the prescriber(s) and the dispenser(s) of the controlled substance(s) and provide all relevant prescription monitoring information to those persons through an established letter of notification.
14- 118 C.M.R. ch. 11, § 9