Authority: IC 16-19-3-4; IC 16-41-2-1
Affected: IC 15-17-6-11; IC 16-41-2; IC 16-41-9
Sec. 80.
Animal Type | Evaluation and Disposition of Animal | Postexposure Prophylaxis Recommendation | |
Dogs, cats, and ferrets | Healthy and available for 10 day observation1 | Should not begin prophylaxis unless animal develops symptoms of rabies2 | |
Rabid or suspected rabid | Immediate postexposure prophylaxis | ||
Unknown | Consult public health officials | ||
Skunks, raccoons, bats3, foxes and most other wild carnivores, including those animals kept in captivity or as pets | Regard as rabid unless geographic area is known to be free of rabies or until animal is proven negative by laboratory testing4 | Immediate postexposure prophylaxis if animal is unavailable for testing, or if animal is available for testing, as soon as a positive result is observed | |
Livestock, rodents, and lagomorphs (rabbits and hares) | Consider individually | Consult public health officials. Bites from squirrels, hamsters, guinea pigs, gerbils, chipmunks, rats, mice, other rodents, rabbits, and hares almost never require antirabies treatment. Bites from larger rodents (groundhogs, beavers, muskrats) may require antirabies treatment. | |
1If the animal is unhealthy or has a serious injury that would make quarantine inhumane, the stray animal may be euthanized immediately and the head submitted to the rabies laboratory. | |||
2Postexposure prophylaxis should be started if a veterinarian identifies an animal as being symptomatic. Symptomatic animals should be euthanized and tested immediately. | |||
3What appears to be insignificant contact with bats may result in rabies transmission, even without clear evidence of a bite. | |||
Postexposure prophylaxis is recommended for all persons with bite, scratch, or mucous membrane exposure to a bat unless the bat is available for testing and is negative for rabies. Postexposure prophylaxis is appropriate even in the absence of bite, scratch, or mucous membrane exposure in situations in which there is a reasonable probability that such contact occurred (for example, a sleeping individual awakes to find a bat in the room, an adult witnesses a bat in the room with a previously unattended child, mentally challenged person, or intoxicated person) and rabies cannot be ruled out by testing the bat. | |||
4The animal should be euthanized and tested as soon as possible. Holding for observation is not allowable as time lapse from virus secretion in saliva until clinical symptoms appear have not been determined for species other than a dog, cat, or ferret. Consult with the department veterinary epidemiologist for information on presence or absence of rabies in particular species. |
Guidelines for Postexposure Prophylaxis | ||
Vaccination Status | Treatment | Regimen* |
Not previously vaccinated | Local wound cleaning | All postexposure treatment should begin with immediate thorough cleansing of all wounds with soap and water. |
Human rabies immune globulin (HRIG) | 20 IU/kg body weight. If anatomically feasible, the full dose should be infiltrated around the wound or wounds. Any remaining volume should be administered intramuscularly at a site distant from vaccine inoculation. | |
Vaccine | Human diploid cell vaccine (HDCV), purified chick embryo cell vaccine (PCEC), or rabies vaccine adsorbed (RVA), 1.0 ml, IM (deltoid1), one dose should be given on days 0, 3, 7, and 14. Immunocompromised individuals may require a 5th vaccine dose to be given on day 28. | |
Previously vaccinated2 | Local wound cleaning | All postexposure treatment should begin with immediate thorough cleansing of all wounds with soap and water. |
HRIG | Should not be administered to individuals who have been previously vaccinated. | |
Vaccine | HDCV, PCEC, or RVA, 1.0 ml IM (deltoid1), one dose should be given on days 0 and 3. | |
*These regimens are applicable for all age groups, including children. | ||
1The deltoid area is the only acceptable site of vaccination for adults and older children. For younger children, the outer aspect of the thigh may be used. The vaccine should never be administered in the gluteal area. The vaccine should never be administered in the same location with the HRIG. | ||
2Any person with a history of preexposure vaccination with HDCV or RVA, prior postexposure prophylaxis with HDCV or RVA, or previous vaccination with any other type of rabies vaccine and a documented history of antibody response to the prior vaccination. |
410 IAC 1-2.5-80