Philip Morris Products S.A.Download PDFPatent Trials and Appeals BoardApr 30, 20212020005214 (P.T.A.B. Apr. 30, 2021) Copy Citation UNITED STATES PATENT AND TRADEMARK OFFICE UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O. Box 1450 Alexandria, Virginia 22313-1450 www.uspto.gov APPLICATION NO. FILING DATE FIRST NAMED INVENTOR ATTORNEY DOCKET NO. CONFIRMATION NO. 14/409,664 12/19/2014 Florian Martin 4058.0060002 7918 155543 7590 04/30/2021 STERNE, KESSLER, GOLDSTEIN & FOX P.L.L.C. 1100 NEW YORK AVENUE, N.W. WASHINGTON, DC 20005 EXAMINER HARWARD, SOREN T ART UNIT PAPER NUMBER 1631 NOTIFICATION DATE DELIVERY MODE 04/30/2021 ELECTRONIC Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. Notice of the Office communication was sent electronically on above-indicated "Notification Date" to the following e-mail address(es): e-office@sternekessler.com PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte FLORIAN MARTIN, ALAIN SEWER, JULIA HOENG, and MANUEL CLAUDE PEITSCH Appeal 2020-005214 Application 14/409,664 Technology Center 1600 Before DEBORAH KATZ, JOHN G. NEW, and ROBERT A. POLLOCK, Administrative Patent Judges. KATZ, Administrative Patent Judge. DECISION ON APPEAL Appellant1 seeks our review,2 under 35 U.S.C. § 134(a), of the Examiner’s decision to reject claims 1–5, 8–15, 18, and 19. We have jurisdiction under 35 U.S.C. § 6(b). We AFFIRM. 1 We use the word Appellant to refer to “applicant” as defined in 37 C.F.R. § 1.42(a). Appellant identifies the real party in interest as Phillip Morris Products S.A. (Appeal Br. 4.) 2 We consider the Final Office Action issued March 12, 2019 (“Final Act.”), the Appeal Brief filed March 23, 2020 (“Appeal Br.”), the Examiner’s Answer issued on May 1, 2020 (“Ans.”), and the Reply Brief filed July 1, 2020 (“Reply Br.”). Appeal 2020-005214 Application 14/409,664 2 Appellant’s Specification is directed to a system and method for identifying biological entities and their properties that are representative of a phenotype of interest. (See Spec. 2:10–12.) The method analyzes the measured activities of biological entities using a network model of a biological system. (See id. at 2:12–14.) The Specification describes the network model as “a mathematical construct that is representative of a dynamic biological system and that is built by assembling quantitative information about various basic properties of the biological system.” (Id. at 15:6–8.) Appellant’s claim 1 recites: A computerized method for identifying biological entities that are representative of a phenotype of interest, comprising the steps of: (a) providing, at a network modeling engine instantiated on a processing device, a computational causal network model that represents a biological system that contributes to the phenotype and includes: a plurality of nodes that represent biological entities in the biological system; and a plurality of edges connecting pairs of nodes among the plurality of nodes and representing relationships between the biological entities represented by the nodes, wherein one or more edges is associated with a direction value that represents a causal activation or causal suppression relationship between the biological entities represented by the nodes, and wherein each node is connected by an edge to at least one other node; (b) receiving, at a network scoring engine instantiated on the processing device, the network scoring engine in communication with the network modeling engine, (i) a first Appeal 2020-005214 Application 14/409,664 3 set of data corresponding to activities of a first subset of biological entities obtained under a first set of conditions; and (ii) a second set of data corresponding to activities of the first subset of biological entities obtained under a second set of conditions different from the first set of conditions, wherein the first and second sets of conditions relate to the phenotype; (c) calculating, with the network scoring engine, a set of activity measures for a first subset of nodes corresponding to the first subset of biological entities, the activity measure representing a difference between the first set of data and the second set of data; (d) generating, with the network scoring engine, based on the computational causal network model and the set of activity measures, a set of activity values for a second subset of nodes representing candidates of biological entities that contribute to the phenotype but whose activities are not measured, by identifying, for each particular node in the second subset of nodes, an activity value that minimizes a difference statement corresponding to an expression or executable statement that represents a difference between the activity value of the particular node and the activity value or activity measure of nodes to which the particular node is connected by an om3 [sic] within the computational causal network model, wherein the difference statement depends on the direction values of the edges in the computational network connecting the nodes and weight values associated with the edges connecting the nodes; and (e) generating, with the network scoring engine using a machine learning technique, a classifier for the phenotypes based on the set of activity measures, the set of activity values, or both. 3 The Examiner identifies that the term “om” should read “edge” as presented in previous claim sets. (Final Act. 2.) Appeal 2020-005214 Application 14/409,664 4 (Appeal Br. 32–33.) Appellant’s independent claim 14 recites a “computer program product comprising non-transitory computer-readable instructions” for performing the method of claim 1. (See id. at 35–36.) Appellant’s independent claim 15 recites a system for performing the method of claim 1. (See id. at 36–37.). The Examiner rejects claims 1–5, 8–15, 18, and 19 under 35 U.S.C. § 101 as being directed to patent-ineligible subject matter. (Final Act. 3–5.) The Examiner also rejects claims 1–3, 5, 13–15, 18, and 19 under 35 U.S.C. § 103(a) over Ladd4 and Chuang.5 (Final Act. 7–11.) The Examiner rejects claims 4 and 5 under 35 U.S.C. § 103(a) over Ladd, Chuang, and Abeel.6 (Final Act. 11–12.) The Examiner rejects claims 8–12 under 35 U.S.C. § 103(a) over Ladd, Chuang, and Toyoshiba.7 (Final Act. 12–14.) 35 U.S.C. § 101 The Examiner rejects claims 1–5, 8–15, 18, and 19 under § 101 as being directed to patent-ineligible subject matter. (Final Act. 3–5; Ans. 4– 8.) Appellant argues claims 1–5, 8–15, 18, and 19 together. (See Appeal Br. 7–25.) We therefore analyze claim 1 as exemplary below. 4 Ladd et al., US Patent Application Publication 2009/0099784 A1, published April 16, 2009. 5 Chuang et al., Network-based classification of breast cancer metastasis, 3 Molecular Systems Biology 140 (2007). 6 Abeel et al., Robust biomarker identification for cancer diagnosis with ensemble feature selection methods, 26 Bioinformatics 392–98 (2010). 7 Toyoshiba et al., Gene Interaction Network Suggests Dioxin Induces a Significant Linkage between Aryl Hydrocarbon Receptor and Retinoic Acid Receptor Beta, 112 Environ. Health Perspect. 1217–24 (2004). Appeal 2020-005214 Application 14/409,664 5 Standard for Subject Matter Eligibility For issues involving subject matter eligibility under § 101, we apply the two-step test set forth in Alice Corp. v. CLS Bank Int’l, 573 U.S. 208 (2014). In the first step, we “determine whether the claims at issue are directed to a patent-ineligible concept.” (Id. at 218.) If the initial threshold is met, we move to the second step, in which we “consider the elements of each claim both individually and ‘as an ordered combination’ to determine whether the additional elements ‘transform the nature of the claim’ into a patent-eligible application.” (Id. at 217 (quoting Mayo Collaborative Servs. v. Prometheus Labs., Inc., 566 U.S. 66, 78–79 (2012))). The second step is “a search for an ‘inventive concept’—i.e., an element or combination of elements that is ‘sufficient to ensure that the patent in practice amounts to significantly more than a patent upon the [ineligible concept] itself.’” (Id. at 217–18 (quoting Mayo, 566 U.S. at 72–73) (alteration in original).) The USPTO has published guidance on the application of § 101. 2019 Revised Patent Subject Matter Eligibility Guidance, 84 Fed. Reg. 50 (Jan. 7, 2019) (“Guidance”). Under the Guidance and the October 2019 Update, we first look to whether the claim recites: (1) any judicial exceptions, including certain groupings of abstract ideas (i.e., mathematical concepts, certain methods of organizing human activity such as a fundamental economic practice, or mental processes) (“Step 2A, Prong 1”); and (2) additional elements that integrate the judicial exception into a practical application (see MPEP § 2106.05(a)–(c), (e)–(h) (9th ed. Rev. 08.2017, Jan. 2018)) (“Step 2A, Prong 2”).8 8 This evaluation is performed by (a) identifying whether there are any additional elements recited in the claim beyond the judicial exception, and (b) evaluating those additional elements individually and in combination to Appeal 2020-005214 Application 14/409,664 6 Guidance, 84 Fed. Reg. at 52–55. Only if a claim (1) recites a judicial exception and (2) does not integrate that exception into a practical application, do we then look, under Step 2B, to whether the claim: (3) adds a specific limitation beyond the judicial exception that is not “well-understood, routine, conventional” in the field (see MPEP § 2106.05(d)); or (4) simply appends well-understood, routine, conventional activities previously known to the industry, specified at a high level of generality, to the judicial exception. Guidance, 84 Fed. Reg. at 52–56. Step 2A, Prong 1 Under Step 2A, Prong 1, of the Guidance, we determine whether the claims recite any judicial exceptions, including certain groupings of abstract ideas (i.e., mathematical concepts, certain methods of organizing human activity, or mental processes). See 84 Fed. Reg. at 52, 54. The Examiner finds that the claimed “computational causal network model” is a mathematical construct that is representative of a dynamic biological system, where the biological system is modeled as a mathematical graph. (Ans. 4, citing Spec. 15:6–7, 28–29.) The Examiner finds that the claims recite additional mathematical concepts, including “calculating,” “generating . . . a score,” and other mathematical expressions. (Id. at 4–5.) Accordingly, the Examiner finds that the claims recite numerous mathematical concepts that are patent ineligible abstract ideas. (See id. at 5.) determine whether the claim as a whole integrates the exception into a practical application. See 2019 Revised Guidance - Section III(A)(2), 84 Fed. Reg. 54–55. Appeal 2020-005214 Application 14/409,664 7 Appellant argues that the independent claims do not: (1) recite mathematical formulas, (2) attempt to textually claim an equation, (3) recite mathematical operators, and (4) expressly recite relationships between variables and numbers. (Appeal Br. 12.) Appellant argues that although the independent claims recite terms that may rely on mathematical concepts, “they do not explicitly recite any mathematical concepts.” (Id. at 13.) As to the specific claim elements, Appellant argues that “the claimed computational causal network merely refers to inferred data based on received input,” as thus is not a component of an algorithm. (Id. at 15.) To further support their argument, Appellant refers to Patent Eligibility Guidance Examples 39 and 41, issued with the 2019 Guidance. (See id. at 15–18.) Appellant argues that the claims are similar to Example 39, which does not explicitly recite mathematical concepts, and are dissimilar to Example 41, which explicitly recites mathematical formulas. (See id.) We agree with the Examiner that the claims recite an abstract idea, namely a mathematical concept. In step (d), independent claim 1 recites: an activity value that minimizes a difference statement corresponding to an expression or executable statement that represents a difference between the activity value of the particular node and the activity value or activity measure of nodes to which the particular node is connected by an [edge] within the computational causal network model, wherein the difference statement depends on the direction values of the edges in the computational network connecting the nodes and weight values associated with the edges connecting the nodes (Appeal Br. 32–33, 36 (claim 14(d)), 37 (claim 15 (b)(iii)).) The Specification describes a specific expression of a difference statement in the form of Equation 6. (See Spec. 26:12–22). The claims appear to textually Appeal 2020-005214 Application 14/409,664 8 recite Equation 6, i.e., (the difference (-) between activity values (f(x), f(y)) of nodes (x and y) connected by an edge (x→y), depending on direction values (sign(x→y)) and weight values (w(x→y)). (See id.) Additionally, the claims recite other mathematical concepts including calculating a set of activity measures representing a difference between data sets. For at least these reasons we find that the claims are distinguishable from those of PEG Example 39. Instead, the claims are similar to PEG Example 41 in that they expressly recite a mathematical expression, although using text rather than mathematical operators. Accordingly, we agree with the Examiner that the claims recite an abstract idea in the category of mathematical concepts under Step 2A, Prong 1 of the Guidance. Step 2A, Prong 2 Under Step 2A, Prong 2, of the Guidance, we determine whether the claims as a whole integrate the judicial exception into a practical application. See 84 Fed. Reg. at 54–55. The Examiner finds that additional elements of the claims recite mere instructions to apply the abstract idea, i.e., mathematical concept, using a generic computer, and therefore the claim does not integrate the abstract idea into a practical application. (See Final Act. 4.) Moreover, the Examiner finds that “[n]one of the dependent claims recite any additional non-abstract elements; they are all directed to further aspects of the information being analyzed, the manner in which that analysis is performed, or the mathematical operations performed on the information.” (Id.) Appellant argues that the claims recite a specific combination of elements for identifying biological entities that are representative of a phenotype of interest. (See Appeal Br. 20.) Appellant argues that the claims Appeal 2020-005214 Application 14/409,664 9 are similar to claims found patent eligible in Appeal No. 2017-003914 and Appeal No. 2019-003792. (See id. at 20–21.) Finally, Appellant argues that the claims are similar to those of PEG Example 37. (Id. at 21–22.) We have considered, but are not persuaded, by Appellant’s arguments. We do not agree that Appellant’s claims recite additional elements that integrate the abstract idea, i.e., mathematical concept, into a practical application. As acknowledged by Appellant’s Specification, a network model of a biological system is a mathematical construct. (See Spec. 15:6– 8.) Accordingly, Appellant’s claims are directed to mathematical concepts that improve the mathematical construct used to identify biological entities. In other words, the claimed additional elements generally link the judicial exception, i.e., mathematical concept, to a particular technological environment, i.e., mathematical constructs of biological systems. But “merely limiting the field of use of the abstract idea to a particular existing technological environment does not render the claims any less abstract.” (Affinity Labs of Texas, LLC v. DIRECTV, LLC, 838 F.3d 1253, 1259 (Fed. Cir. 2016); see also Digitech Image Techs., LLC v. Elecs. for Imaging, Inc., 758 F.3d 1344, 1351 (Fed. Cir. 2014) (“If a claim is directed essentially to a method of calculating, using a mathematical formula, even if the solution is for a specific purpose, the claimed method is nonstatutory.” (quoting Parker v. Flook, 437 U.S. 584, 595 (1978)). Because the alleged improvement is to a mathematical construct, we find these claims to be readily distinguishable from those in Appeal Nos. 2017-003914 and 2019-003792. Moreover, as discussed by the Examiner, the additional elements of the claims, i.e., a computerized process performed on a processing device, all relate to applying the claimed mathematical Appeal 2020-005214 Application 14/409,664 10 concepts using a generic computer and do not improve the computer itself. (See Final Act. 4.) For this reason, we find the claims distinguishable from the claim of PEG Example 37, which relates to a technological improvement rather than merely applying the abstract idea on a computer. Step 2B Under Step 2B of the Guidance, we continue to evaluate patent eligibility by considering whether the claim provides an inventive concept that amounts to significantly more than the exception itself. (See Guidance, 84 Fed. Reg. at 56.) The Examiner finds that: (1) the only non-abstract elements of the claims amount to mere instructions to apply the abstract idea using a generic computer, and (2) that the claims do not provide an inventive concept because the additional elements of the claims are elements of the abstract idea itself. (See Ans. 6–8.) Because the abstract idea itself cannot contribute to an inventive concept, the Examiner does not expressly apply the “well-understood, routine and conventional” analysis to the additional elements of the claims. (See id.; citing Genetic Techs. v. Merial LLC, 818 F.3d 1369, 1376 (Fed. Cir. 2016) (“The inventive concept necessary at step two of the Mayo/Alice analysis cannot be furnished by the unpatentable law of nature (or natural phenomenon or abstract idea) itself.”) Appellant contends that, in addition to any alleged mathematical concepts, the claims recite “details regarding specific components and limitations of the network model,” “a receiving step,” and “actually generating a classifier for the phenotypes using a machine learning technique defined by specific inputs.” (Reply Br. 7–8.) Appellant contends that the Examiner has not provided evidence that these additional claim elements are routine, conventional, or well-known. (See id. at 8.) Appeal 2020-005214 Application 14/409,664 11 We are not persuaded by Appellant’s argument. Rather we agree with the Examiner that the elements cited by Appellant are either insignificant extra-solution activity or part of the abstract idea itself. For example, the receiving step relates to receiving first and second sets of data to be analyzed. Although the data may be specific to biological entities, our reviewing court has held that mere data-gathering steps cannot make an otherwise nonstatutory claim statutory. See CyberSource Corp. v. Retail Decisions, Inc., 654 F.3d 1366, 1370 (Fed. Cir. 2011). Moreover, receiving data for use in a network modeling engine is well-understood, routine, and conventional as established by Ladd, discussed below. Appellant’s other “additional elements,” are part of the mathematical concept itself. For example, the details of the network model, including the nodes, edges, and their relationships, are simply the data points making up the mathematical construct. Similar network models of biological systems, including biological entities represented as nodes connected by edges are taught by Ladd, Chuang, and Toyoshiba, as discussed below. Likewise, generating a classifier using a machine-learning technique is another mathematical concept recited by the claims. The Specification acknowledges that such machine-learning techniques are conventional. (See Spec. 32:24–33:2.) In sum, Appellant does not identify any additional features that constitute an inventive concept. Accordingly, we are not persuaded that the Examiner erred in rejecting Appellant’s pending claims as being directed to ineligible subject matter under 35 U.S.C. § 101. Appeal 2020-005214 Application 14/409,664 12 35 U.S.C. § 103(a) The Examiner rejects Appellant’s claims as being obvious under 35 U.S.C. § 103(a). Specifically, the Examiner rejects claims 1–3, 5, 13–15, 18, and 19 over Ladd and Chuang (see Final Act. 7–11); claims 4 and 5 over Ladd, Chuang, and Abeel (see Final Act. 11–12); and claims 8–12 over Ladd, Chuang, and Toyoshiba (see Final Act. 12–14). Appellant does not raise any separate arguments against any of the claims or groups of claims in the separate rejections. (See Appeal Br. 26–31.) Thus, we focus on claim 1. See 37 C.F.R. § 41.37(c)(1)(iv). Ladd teaches a method for modelling the actions and interactions of biomolecules within a biological system to understand the systematic nature of biological events. (See Ladd ¶ 59.) Ladd specifically teaches a causal system model (“CSM”) which connects “many biological elements or ‘nodes’ into a highly intricate network of relationships and/or connections to form a systematically descriptive, inclusive, and scalable representation of a biological system.” (Id. ¶ 60.) Ladd further teaches “edges,” as the nodes in the model are linked by physical, chemical, or biological relationships, along with a direction of causality between nodes. (See id. ¶ 74.) Ladd teaches that operational data is mapped onto a working knowledge base (“assembly”), and that “algorithms simulate the effect through the assembly of hypothesized increases or decreases in the quantity or activity of nodes within the assembly. This results in generation of a large number of branching paths which involve nodes representative of data points in the operational data set.” (Id. ¶ 76.) Ladd teaches evaluating the models for richness (“number of nodes in the model which map onto the data is greater Appeal 2020-005214 Application 14/409,664 13 than the number that would map by chance”), and concordance (“what fraction of nodes correspond to the operational data”). (Id. ¶¶ 77, 122.) The Examiner finds that Ladd teaches steps (a) through (d) of Appellant’s claim 1, including: (a) providing a causal system model comprising nodes that represent biological entities and directional relationships between nodes (edges); (b) receiving quantitative data corresponding to the entities for at least two different biological states; (c) comparing node similarities and dissimilarities; and (d) applying algorithms to the data to analyze concordance, which correspond to each step of the recited method, except step [e]. (See Final Act. 8–10.) The Examiner finds that Chuang teaches a network-based method for analyzing differential gene expression in breast cancer. (See Final Act. 10.) The Examiner finds Chuang applies a greedy search algorithm, which is a machine-learning technique, to classify the data. (See id.) The Examiner finds that a person of ordinary skill in the art would have been motivated to combine Ladd’s causal system model with Chuang’s network-based system for identifying biomarkers “because Chuang teaches that network based biomarker identification has various advantages over methods than identify biomarkers independently.” (Id. at 11.) The Examiner further finds that because both Ladd and Chuang teach network-based methods for analyzing biological pathways, a person of ordinary skill would have had a reasonable expectation of success in “using a CSM to predict expressions of unobserved genes from gene expression measurements, and then using the observed and predicted measurements to create a classifier that distinguishes between” phenotypes, e.g., metastatic and non-metastatic cancer. (Id.) Appeal 2020-005214 Application 14/409,664 14 Appellant argues that Ladd does not teach the limitations of step (d), particularly an “expression or executable statement,” and “a difference statement would not represent a difference between an activity value generated for a particular node and an activity value generated for a node connected to the particular node’s edge.” (Appeal. Br. 29–30.) We address each argument in turn. First, Appellant argues that Ladd does not teach an “expression or executable statement” because “Ladd does not disclose or suggest that the ‘case frames’ include ‘functional descriptions of mathematical relationships.’” (Appeal Br. 29.) We are not persuaded by Appellant’s argument. Ladd generally teaches that causal modeling of relationships in biological systems may be combined with artificial intelligence “to generate millions of potential hypotheses, which are then evaluated through a number of algorithms to produce a set of statistically significant hypotheses.” (Ladd ¶ 70.) More specifically, Ladd teaches a class of algorithms that may be used to adjust the causal model. (See Ladd ¶ 112.) For example, Ladd teaches applying “combinatorial space search algorithms, such as a genetic algorithm, simulated annealing, evolutionary algorithms, and the like, to the multiple branching paths using as a fitness function the number of correctly simulated data points in the candidate path combinations.” (Id. ¶ 118.) Moreover, Ladd teaches applying richness and concordance algorithms to differentiate between models. (See id. ¶¶ 121–123; Figs. 5–14.) Each of the specific algorithms taught by Ladd include underlying functional descriptions of mathematical relationships, and thus teach expressions or executable Appeal 2020-005214 Application 14/409,664 15 statements within those algorithms. Accordingly, we are not persuaded that the Examiner erred. Second, Appellant argues that Ladd does not teach minimizing a difference statement representing a difference between the activity value of a particular node, and the activity value of nodes to which the particular node is connected by an edge within the computational casual network model. (See Reply Br. 8.) According to Appellant, Ladd’s fitness function is not being used to minimize the difference between the results of the CSM and the operational data. (Id. at 10.) The Examiner responds that Ladd teaches preferring models with “concordance,” which is synonymous with “minimal difference.” (Ans. 10.) The Examiner finds that Ladd’s fitness function would have been used to minimize the difference between the simulation results of the CSM and operational data. (Id.) Accordingly, the Examiner finds that simulating a highly concordant CSM would calculate activity values that minimize the difference statement between the activity value of the particular node, and the activity value of nodes connected by an edge to the particular node. (Id.) We agree with the Examiner that the claims would have been obvious over the cited prior art. Ladd teaches a causal network including a plurality of nodes connected by directional edges, including nodes with and without operational data. (See Ladd Figs. 5–14.) Ladd optimizes based on concordance between simulation results and operational data, and teaches various algorithms used to minimize the difference between activity levels in the models. (See Ladd ¶ 122.) Part of Ladd’s concordance analysis compares the predicted activity increase or decrease between nodes, and thus minimizes a difference between the activity values of nodes connected by Appeal 2020-005214 Application 14/409,664 16 edges. (See id.) Although, Ladd does not disclose an identical difference statement to the claimed difference statement, the obviousness “analysis need not seek out precise teachings directed to the specific subject matter of the challenged claim, for a court can take account of the inferences and creative steps that a person of ordinary skill in the art would employ.” KSR Int'l Co. v. Teleflex Inc., 550 U.S. 398, 418 (2007). The Examiner has articulated reasoning for extrapolating a conclusion of prima facie obviousness from the prior art, by applying such inferences and creative steps. See Perfect Web Techs., Inc. v. InfoUSA, Inc., 587 F.3d 1324, 1330 (Fed. Cir. 2009). Appellant has not persuasively rebutted the Examiner’s articulated reasoning. Appellant does not persuade us that the Examiner erred in rejecting claim 1 as being obvious. Appellant fails to present separate arguments for the rejection of any other of the pending claims. Accordingly, we sustain each of the rejections under 35 U.S.C. § 103(a). DECISION SUMMARY Upon consideration of the record and for the reasons given, we affirm the Examiner’s rejection. In summary: Claim(s) Rejected 35 U.S.C. § Reference(s)/Basis Affirmed Reversed 1–5, 8– 15, 18, 19 101 Eligibility 1–5, 8–15, 18, 19 1–3, 5, 13–15, 18, 19 103(a) Ladd, Chuang 1–3, 5, 13– 15, 18, 19 4, 5 103(a) Ladd, Chuang, Abeel 4, 5 Appeal 2020-005214 Application 14/409,664 17 8–12 103(a) Ladd, Chuang, Toyoshiba 8–12 Overall Outcome 1–5, 8–15, 18, 19 No time period for taking any subsequent action in connection with this appeal may be extended under 37 C.F.R. § 1.136(a). See 37 C.F.R. § 1.136(a)(1)(iv). AFFIRMED Copy with citationCopy as parenthetical citation