KAMEN, Ali et al.Download PDFPatent Trials and Appeals BoardNov 2, 20212020005534 (P.T.A.B. Nov. 2, 2021) Copy Citation UNITED STATES PATENT AND TRADEMARK OFFICE UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O. Box 1450 Alexandria, Virginia 22313-1450 www.uspto.gov APPLICATION NO. FILING DATE FIRST NAMED INVENTOR ATTORNEY DOCKET NO. CONFIRMATION NO. 14/442,517 05/13/2015 Ali Kamen 2012P26792WOUS 7962 28524 7590 11/02/2021 SIEMENS CORPORATION IP Dept - Mail Code INT-244 3850 Quadrangle Blvd Orlando, FL 32817 EXAMINER LEE, TSU-CHANG ART UNIT PAPER NUMBER 2128 NOTIFICATION DATE DELIVERY MODE 11/02/2021 ELECTRONIC Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. Notice of the Office communication was sent electronically on above-indicated "Notification Date" to the following e-mail address(es): ipdadmin.us@siemens.com PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte ALI KAMEN, MANEESH KUMAR SINGH, SEBASTIAN POELSTERL, LANCE ANTHONY LADIC, and DORIN COMANICIU Appeal 2020-005534 Application 14/442,517 Technology Center 2100 Before BRADLEY W. BAUMEISTER, MINN CHUNG, and PHILLIP A. BENNETT, Administrative Patent Judges. BENNETT, Administrative Patent Judge. DECISION ON APPEAL STATEMENT OF THE CASE Pursuant to 35 U.S.C. § 134(a), Appellant1 appeals from the Examiner’s decision to reject claims 1, 8, 13, 20, 22–26, 28–30, and 32–34. We have jurisdiction under 35 U.S.C. § 6(b). We affirm. 1 “Appellant” refers to “applicant” as defined in 37 C.F.R. § 1.42(a). Appellant identifies the real parties in interest as Siemens Healthcare Diagnostic Inc. and Siemens Healthcare GmbH. Appeal Br. 1. Appeal 2020-005534 Application 14/442,517 2 CLAIMED SUBJECT MATTER The claims are directed to a method to identify optimum coronary artery disease treatment. Claim 1, reproduced below, is illustrative of the claimed subject matter: 1. A method of identifying an optimum treatment for a patient suffering from coronary artery disease, the method comprising: (i) providing one or more items of patient information selected from: (A) status in the patient of one or more biomarkers associated with coronary heart disease; (B) one or more items of medical history information of the patient selected from prior condition history, medical intervention history, and medication history; (C) one or more items of diagnostic history of the patient; and (D) one or more items of patient demographic data; (ii) aggregating the patient information in at least one of: (a) a Bayesian network; (b) a machine learning and neural network; (c) a rule-based system; or (d) a regression-based system; and (iii) determining a recommended intervention for the patient using a cascaded series of tests based on the aggregated patient information by: deriving, using the at least one of the Bayesian network, the machine learning and neural network, the rule-based system, or the regression-based system based on a first set of patient information input to the at least one of the Bayesian network, the machine learning and neural network, the rule-based system, or the regression-based system, a predicted probability of target vessel Appeal 2020-005534 Application 14/442,517 3 revascularization (TVR) for a bare metal stent percutaneous coronary intervention; in response to a determination that the predicted probability of TVR for the bare metal stent percutaneous coronary intervention is less than a first threshold, determining the bare metal stent percutaneous coronary intervention to be the recommended intervention for the patient; in response to a determination that the predicted probability of TVR for the bare metal stent percutaneous coronary intervention is not less than the first threshold, deriving, using the at least one of the Bayesian network, the machine learning and neural network, the rule-based system, or the regression-based system based on a second set of patient information input to the at least one of the Bayesian network, the machine learning and neural network, the rule-based system, or the regression-based system, a predicted probability of a major adverse cardiac event (MACE) for a drug-eluting stent percutaneous coronary intervention, wherein the second set of patient information includes patient age, patient gender, diabetes condition of the patient, diagnostic history information of the patient, and CRP, CREA, DbTNT, parallel TNT, HsTNT and NTproBNP biomarkers; in response to a determination that the predicted probability of a MACE for the drug-eluting stent percutaneous coronary intervention is not greater than a second threshold, determining the drug-eluting stent percutaneous coronary intervention to be the recommended intervention for the patient; and in response to a determination that the predicted probability of a MACE for the drug-eluting stent percutaneous coronary intervention is greater than the second threshold, determining a coronary artery bypass grafting to be the recommended intervention for the patient. Appeal Br. 17–18 (Claims Appendix). Appeal 2020-005534 Application 14/442,517 4 REJECTIONS Claims 1, 8, 13, 20, 22–26, 28–30, and 32–33 stand rejected under 35 U.S.C. § 101 as being directed to ineligible subject matter. Final Act. 3– 5. ANALYSIS Standard for Patent Eligibility In issues involving subject matter eligibility, our inquiry focuses on whether the claims satisfy the two-step test set forth by the Supreme Court in Alice Corp. v. CLS Bank Int’l, 573 U.S. 208 (2014). The Court instructs us to “first determine whether the claims at issue are directed to a patent- ineligible concept,” id. at 218, and, in this case, the inquiry centers on whether the claims are directed to an abstract idea. If the initial threshold is met, we then move to the second step, in which we “consider the elements of each claim both individually and ‘as an ordered combination’ to determine whether the additional elements ‘transform the nature of the claim’ into a patent-eligible application.” Id. at 217–18 (quoting Mayo Collaborative Servs. v. Prometheus Labs., Inc., 566 U.S. 66, 79, 78 (2012)). The Court describes the second step as a search for “an ‘“inventive concept”’—i.e., an element or combination of elements that is ‘sufficient to ensure that the patent in practice amounts to significantly more than a patent upon the [ineligible concept] itself.’” Id. (quoting Mayo, 566 U.S. at 72–73). The USPTO has published revised guidance on the application of § 101 consistent with Alice and subsequent Federal Circuit decisions. USPTO, 2019 Revised Patent Subject Matter Eligibility Guidance, 84 Fed. Reg. 50 (Jan. 7, 2019) (“Guidance”), updated by USPTO, October 2019 Appeal 2020-005534 Application 14/442,517 5 Update: Subject Matter Eligibility (available at https://www.uspto.gov/sites/ default/files/documents/peg_oct_2019_update.pdf) (“October Update”). Under the Guidance, we first look to whether the claim recites: (1) any judicial exceptions, including certain groupings of abstract ideas (i.e., mathematical concepts, certain methods of organizing human activity such as a fundamental economic practice, or mental processes) (referred to Step 2A, prong 1 in the Guidance); and (2) additional elements that integrate the judicial exception into a practical application (see MPEP § 2106.05(a)–(c), (e)–(h) (9th ed. Rev. 10.2019, rev. June 2020)) (referred to Step 2A, prong 2 in the Guidance). See Guidance, 84 Fed. Reg. at 52–55. Only if a claim (1) recites a judicial exception and (2) does not integrate that exception into a practical application, do we then move to Step 2B of the Guidance. There, we look to whether the claim: (3) adds a specific limitation beyond the judicial exception that is not “well-understood, routine, conventional” in the field (see MPEP § 2106.05(d)); or (4) simply appends well-understood, routine, conventional activities previously known to the industry, specified at a high level of generality, to the judicial exception. See Guidance, 84 Fed. Reg. at 56. Examiner’s Findings and Conclusions The Examiner rejects claim 1 as being directed to a judicial exception without reciting significantly more under the Guidance. Final Act. 2–4. Under Step 2A, prong 1, the Examiner determines that most of the limitations of claim 1 recite an abstract idea of a mental process under the Guidance. Final Act. 4; Ans. 4–6. The Examiner states that “these steps are very similar to the thought process using logic rules performed in a Appeal 2020-005534 Application 14/442,517 6 physician’s mind while making recommended treatment based on observation of information collected about a patient. Hence this limitation is a mental process.” Final Act. 4. Under Step 2A, prong 2, the Examiner determines the only steps that do not recite a mental process involve “additional elements that collect patient information, which add insignificant extra-solution activity to the judicial exception.” Final Act. 4 (citing MPEP § 2106.05(g)). Under Step 2B, the Examiner determines that those same patient- information-collection limitations do “not include additional elements that are sufficient to amount to significantly more than the judicial exception” because they amount only to insignificant extra-solution activity. Final Act. 4–5. The Examiner explains that “the nature of the recited elements are directed to a process practiced in a medical doctor to predict failure probability of medical treatments based on collected data about patients with decision rules of his medical knowledge / training, hence the process claimed is directed to a mental process which can be performed by human mind.” Ans. 9. Appellant’s Contentions Appellant argues the claims do not recite an abstract idea under Step 2A, prong 1, because the limitations in the claim cannot practically be performed in the human mind. Appeal Br. 11–12. More specifically, Appellant contends “[t]he claims explicitly require at least one of a Bayesian network, a machine learning and neural network, a rule-based system, or a regression-based system.” Appeal Br. 12. Appellant further argues: The “deriving” steps in the claims cannot practically be performed in the human mind. For instance, a human would not be able to derive a predicted probability of a major adverse Appeal 2020-005534 Application 14/442,517 7 cardiac event for a drug-eluting stent percutaneous coronary intervention from such patient information as patient age, patient gender, diabetes condition of the patient, diagnostic history information of the patient, and CRP, CREA, DbTNT, parallel TNT, HsTNT and NTproBNP biomarkers, as provided for in claim 1. Such derivation of the predicted probability involves aggregating such potentially large amounts of patient information, which is a computationally difficult task that human minds are not equipped to handle. Appeal Br. 12–13. Appellant also challenges the Examiner’s determination with respect to Step 2A, prong 2. Appellant argues each of the claims “require[s] ‘determining a recommended intervention for the patient using a cascaded series of tests based on the aggregated information,’” and “define[s] a particular treatment or prophylaxis for the recommended intervention.” Appeal Br. 14. Appellant asserts that “[t]hese explicit treatments or prophylaxes are practical applications and the claims clearly do not encompass all applications of a judicial exception.” Appeal Br. 14. Appellant additionally asserts that independent claim 13 includes a further requirement of “initiating treatment of the patient with the recommended intervention determined for the patient,” which “is not an extra-solution activity, but is the end result of independent claim 13.” Appeal Br. 14 (emphasis omitted). Under Step 2B, Appellant contends, “the claims recite significantly more than the abstract idea itself.” Appeal Br. 15. Specifically, Appellant argues that the claims require deriving a predicted probability based on “patient age, patient gender, diabetes condition of the patient, diagnostic history information of the patient, [and various biomarkers].” Appeal Br. 15. Appellant contends that “[a]t least these limitations of independent Appeal 2020-005534 Application 14/442,517 8 claims 1, 13, and 24 are not well-understood, routine, or conventional.” Appeal Br. 15. Revised Guidance, Step 2A, Prong 12 The Judicial Exception Applying the Guidance, we are not persuaded the Examiner has erred in determining that the claims recite a judicial exception to patent eligible subject matter. The Guidance identifies three judicially-excepted groupings: (1) mathematical concepts, (2) certain methods of organizing human activity such as fundamental economic practices and commercial interactions, and (3) mental processes. We focus our analysis on the third grouping—mental processes.3 We conclude claim 1 recites a mental process under the Guidance. For example, claim 1 recites “(i) providing one or more items of patient information selected from: (A) status in the patient of one or more biomarkers associated with coronary heart disease; (B) one or more items of medical history information of the patient selected from prior condition 2 Throughout this opinion, we give the claim limitations the broadest reasonable interpretation consistent with the Specification. See In re Morris, 127 F.3d 1048, 1054 (Fed. Cir. 1997). 3 With the exception of a particularized argument with respect to claim 13 made in connection with and addressed by us in Step 2A, prong 2, Appellant’s arguments against the § 101 rejection are made to the claims generally, and we treat claim 1 as representative. 37 C.F.R. § 41.37(c)(1)(iv) (2018) (“When multiple claims subject to the same ground of rejection are argued as a group or subgroup by appellant, the Board may select a single claim from the group or subgroup and may decide the appeal as to the ground of rejection with respect to the group or subgroup on the basis of the selected claim alone.”). Appeal 2020-005534 Application 14/442,517 9 history, medical intervention history, and medication history; (C) one or more items of diagnostic history of the patient; and (D) one or more items of patient demographic data.” Appeal Br. 17 (Claims Appendix). We agree with the Examiner that these limitations recite a mental process under the Guidance because providing patient information can be performed by a person by sharing the information verbally or writing down the patient information on a piece of paper. Although the claim specifies four detailed categories of information that may be provided (items (A) through (D)), each of these categories of patient information remains just that— information that can be shared. Claim 1 also recites “(ii) aggregating the patient information in at least one of: (a) A Bayesian network; (b) a machine learning and neural network; (c) a rule-based system, or (d) a regression-based system.” Appeal Br. 17 (Claims Appendix). Aggregating patient information in a rule-based system falls within the mental process category of the Guidance. As we noted above, the recited “patient information” may be provided verbally or on a piece of paper. Aggregating this information can be accomplished by a person using their mind to input the data into a series of judgments and determinations that make up a “rule-based system,” as claimed. Appellant argues that a person cannot practically perform such an aggregation using their mind because of the large volume of information that would need to be collected. However, this argument is not consistent with the language of the claim. The claim requires that the patient information include “one or more” items of each category of information. Thus, the “patient information” that is aggregated may be as few as only four items of information that need to be aggregated. Appeal 2020-005534 Application 14/442,517 10 Furthermore, even if the claimed information were to require the aid of paper and pencil to accomplish the aggregation in a rule-based system, the 2019 Guidance expressly recognizes such aided mental processes as constituting patent-ineligible abstract ideas. 2019 Guidance, 84 Fed. Reg. at 52; see also October 2019 Guidance Update at 9 (“A claim that encompasses a human performing the step(s) mentally with the aid of a pen and paper recites a mental process”) (emphasis omitted). Claim 1 additionally recites “(iii) determining a recommended intervention for the patient using a cascaded series of tests based on the aggregated patient information.” This limitation also recites an abstract mental process under the Guidance because it can be performed by a human in their mind either through observation, evaluation, and judgment. See October 2019 Guidance Update at 7 (“examples of mental processes include observations, evaluations, judgments, and opinions”). Claim 1 additionally specifies a series of actions that are used to determine the recommended intervention: deriving, using the at least one of the Bayesian network, the machine learning and neural network, the rule-based system, or the regression-based system based on a first set of patient information input to the at least one of the Bayesian network, the machine learning and neural network, the rule-based system, or the regression-based system, a predicted probability of target vessel revascularization (TVR) for a bare metal stent percutaneous coronary intervention; in response to a determination that the predicted probability of TVR for the bare metal stent percutaneous coronary intervention is less than a first threshold, determining the bare metal stent percutaneous coronary intervention to be the recommended intervention for the patient; Appeal 2020-005534 Application 14/442,517 11 in response to a determination that the predicted probability of TVR for the bare metal stent percutaneous coronary intervention is not less than the first threshold, deriving, using the at least one of the Bayesian network, the machine learning and neural network, the rule-based system, or the regression-based system based on a second set of patient information input to the at least one of the Bayesian network, the machine learning and neural network, the rule-based system, or the regression-based system, a predicted probability of a major adverse cardiac event (MACE) for a drug-eluting stent percutaneous coronary intervention, wherein the second set of patient information includes patient age, patient gender, diabetes condition of the patient, diagnostic history information of the patient, and CRP, CREA, DbTNT, parallel TNT, HsTNT and NTproBNP biomarkers; in response to a determination that the predicted probability of a MACE for the drug-eluting stent percutaneous coronary intervention is not greater than a second threshold, determining the drug-eluting stent percutaneous coronary intervention to be the recommended intervention for the patient; and in response to a determination that the predicted probability of a MACE for the drug-eluting stent percutaneous coronary intervention is greater than the second threshold, determining a coronary artery bypass grafting to be the recommended intervention for the patient. Appeal Br. 17–18 (Claims Appendix). These limitations also encompass mental processes under the Guidance. The first limitation recites “deriving . . . a predicted probability of target vessel revascularization (TVR) for a bare metal stent percutaneous coronary intervention.” We agree with the Examiner that deriving a predicted probability can be performed by a person using their mind or with the aid of pen and paper. Appeal 2020-005534 Application 14/442,517 12 Appellant argues the recited derivation requires “using the at least one of the Bayesian network, the machine learning and neural network, the rule- based system, or the regression-based system,” and cannot practically be performed by a person because it “involves aggregating such potentially large amounts of patient information, which is a computationally difficult task that human minds are not equipped to handle.” Appeal Br. 12–13. We disagree with Appellant. As noted above, as drafted, the aggregated patient information may include as few as four items of information. Moreover, the “deriving” limitation specifies that the recited derivation requires “using at least one of” the four specified techniques. However, as the Examiner correctly points out, the use of only one of those four specified techniques is required for the recited derivation. Ans. 4. We agree with the Examiner that deriving a predicted probability using a “rule- based system” can be performed by a human applying a set of rules to observe to data using their mind. We specifically agree with the Examiner that the broad recitation of deriving a predicted probability using a “rule- based system” encompasses a situation in which “a rule[-]based process is used by a medical doctor to perform diagnosis and inference based on collected data related to patients.” Ans. 4. Appellant asserts the Examiner’s position is unsupported because a “rule-based system” requires a computer and not merely the thought process of a medical professional. We disagree because Appellant’s argument confines the word “system” to an overly narrow meaning inconsistent with its broadest reasonable interpretation and use in the Specification. For example, the Specification described a rule-based system as “where the knowledge of domain experts are captured and expressed using a set of rules Appeal 2020-005534 Application 14/442,517 13 which are chained based on the sequence of events to predict an outcome.” Spec. 13, ll. 2–4. Thus, the Specification provides no indication that the claimed “system” must be a computer-based system, as Appellant contends. The remaining limitations have similar derivations of predicted probabilities, and determinations of recommended interventions based on those derived, predicted, probabilities. For the same reasons discussed above, these limitations also are abstract mental processes under the Guidance. Accordingly, we conclude the claimed process set forth in claim 1 recites judicial exceptions of a mental process and a mathematical calculation under the Guidance. Revised Guidance, Step 2A, Prong 2 Integration of the Judicial Exception into a Practical Application Having determined that claim 1 recites a judicial exception, our analysis under the Guidance turns now to determining whether claim 1 recites any additional elements that integrate the judicial exception into a practical application. See Guidance, 84 Fed. Reg. at 54–55 (citing MPEP § 2106.05(a)–(c), (e)–(h)). Under the Guidance, limitations that are indicative of “integration into a practical application” include: 1. Improvements to the functioning of a computer, or to any other technology or technical field — see MPEP § 2106.05(a); 2. Applying the judicial exception with, or by use of, a particular machine — see MPEP § 2106.05(b); 3. Effecting a transformation or reduction of a particular article to a different state or thing — see MPEP § 2106.05(c); and Appeal 2020-005534 Application 14/442,517 14 4. Applying or using the judicial exception in some other meaningful way beyond generally linking the use of the judicial exception to a particular technological environment, such that the claim as a whole is more than a drafting effort designed to monopolize the exception — see MPEP § 2106.05(e). In contrast, limitations that are not indicative of “integration into a practical application” include: 1. Adding the words “apply it” (or an equivalent) with the judicial exception, or merely include instructions to implement an abstract idea on a computer, or merely uses a computer as a tool to perform an abstract idea — see MPEP § 2106.05(f); 2. Adding insignificant extra-solution activity to the judicial exception — see MPEP § 2106.05(g); and 3. Generally linking the use of the judicial exception to a particular technological environment or field of use — see MPEP § 2106.05(h). See Guidance, 84 Fed. Reg. at 54–55 (“Prong Two”). As shown above, all limitations in claim 1 recite only abstract ideas. As a result, there are no additional limitations in the claim to evaluate under Step 2A, prong 2. As we noted above, Appellant asserts the claims are eligible under Prong 2 because they “are integrated into the practical application of treating, and identifying an optimum treatment for, a patient suffering from coronary artery disease.” Appeal Br. 13. To that end, Appellant argues each of the independent claims require “determining a recommended intervention for the patient using a cascaded series of tests based on the aggregated patient information,” and they identify “a particular Appeal 2020-005534 Application 14/442,517 15 treatment or prophylaxis for the recommended intervention.” Appeal Br. 14. According to Appellant, “[t]hese explicit treatments or prophylaxes are practical applications and the claims clearly do not encompass all applications of a judicial exception.” Appeal Br. 14. We are not persuaded by Appellant’s arguments. Independent claims 1 and 24 do not integrate the abstract idea into a practical application because they are limited to determining recommended interventions. These claims do not recite any steps of actually administering any treatment or prophylaxis. Thus, while various treatments may be determined, the mere determination of those treatments is not sufficient to integrate the abstract idea into a practical application. Appellant asserts that claim 13 goes further than the other claims because it “explicitly recites a ‘method of treating a patient suffering from coronary artery disease’ requiring ‘initiating treatment of the patient with the recommended intervention determined for the patient.’” Appeal Br. 14. We are not persuaded that claim 13 requires a different result. The October Update provides guidance on “applying or using [a] judicial exception to effect a particular treatment or prophylaxis for a disease or medical condition.” October Update 13. Specifically, the October Update explains that “treatment or prophylaxis limitation must be ‘particular,’ i.e., specifically identified so that it does not encompass all applications of the judicial exception(s).” October Update 14. Claim 13 concludes with the limitation “initiating treatment of the patient with the recommended intervention determined for the patient.” Appeal Br. 20 (Claims Appendix). This limitation does not meet the requirement that the treatment or prophylaxis limitation be particular. Appeal 2020-005534 Application 14/442,517 16 Rather, it is more akin to a recitation of a generalized instruction to administer a suitable treatment to a patient. Appellant argues that various specified treatment options are recited in the claim. We disagree that merely specifying various treatment options necessarily constitutes setting them forth in a specific and particularized way. And in fact, the selection of the various treatment options, as claimed, is not set forth in a specific and particularized way. For example, the recommendation of a “drug-eluting stent percutaneous coronary intervention” is made “in response to a determination that the predicted probability . . . is not greater than a second threshold.” Appeal Br. 20 (Claims Appendix). Thus, the claim does not identify with specificity or particularity what this threshold is, and thus does not convey with particularity when that particular treatment option is to be selected. Instead it provides an unspecified threshold for selecting that particular treatment option. As such, the changed system design does not provide a sufficient basis for integrating the abstract idea into a practical application, and we agree with the Examiner that the claim is directed to a judicial exception. The Inventive Concept – Step 2B Having determined the claim is directed to a judicial exception, we proceed to evaluating whether claim 1 adds a specific limitation beyond the judicial exception that is not “well-understood, routine, conventional” in the field (see MPEP § 2106.05(d)) or simply appends well-understood, routine, conventional activities previously known to the industry, specified at a high level of generality, to the judicial exception. See Guidance, 84 Fed. Reg. at 56. As we noted above, all of the limitations of claim 1 recite only Appeal 2020-005534 Application 14/442,517 17 abstract ideas. None of the limitations recite any additional elements beyond the abstract idea. As such, there are no additional elements in the claim that could be sufficient to supply an inventive concept. Appellant argues it is not well understood, routine, or convention to derive a predicted probability “based on ‘patient age, patient gender, diabetes condition of the patient, diagnostic history information of the patient, and CRP, CREA, DbTNT, parallel TNT, HsTNT and NTproBNP biomarkers.’” Appeal Br. 18. This argument is not persuasive because these limitations solely recite abstract ideas, as the recited “deriving” is a mental process under the Guidance, as we explained above. As the Examiner correctly explains, “the nature of the recited elements are directed to a process practiced in a medical doctor to predict failure probability of medical treatments based on collected data about patients with decision rules of his medical knowledge / training.” Ans. 9. Because the Examiner correctly concluded claim 1 is directed to a judicial exception, and because Appellant does not identify any additional elements beyond the noted abstract ideas, Appellant does not demonstrate error in the Examiner’s determination under step 2B of the Guidance. We, therefore, sustain the rejection of representative claim 1 under 35 U.S.C. § 101, as well as of the independent claim 24. With respect to independent claim 13, we also do not find the recitation of “initiating treatment of the patient with the recommended intervention determined for the patient” sufficient to supply an inventive concept. We first note that Appellant does not advance any argument that the “initiating treatment” step supplies an inventive concept under Step 2B. See Appeal Br. 18; Reply Br. 3–4. Second, the reasons that the “initiating Appeal 2020-005534 Application 14/442,517 18 treatment” step does not amount to a practical application under Step 2A, prong 2 apply equally here. As explained above, the treatment step does not identify with specificity or particularity what this threshold value for selecting any particular treatment, and thus does not convey with particularity when any particular treatment option is to be selected. As such, we also sustain the rejection of claim 13 under 35 U.S.C. § 101. Remaining Claims Appellant presents no other arguments for separate patentability of any other claims. Accordingly, we sustain the Examiner’s rejections of these claims for the reasons stated with respect to the independent claims from which they depend. See 37 C.F.R. § 41.37(c)(1)(iv). CONCLUSION We affirm the Examiner’s decision to reject the claims. DECISION SUMMARY Claim(s) Rejected 35 U.S.C. § Reference(s)/Basis Affirmed Reversed 1, 8, 13, 20, 22–26, 28– 30, 32–34 101 Eligibility 1, 8, 13, 20, 22–26, 28– 30, 32–34 TIME PERIOD FOR RESPONSE No time period for taking any subsequent action in connection with this appeal may be extended under 37 C.F.R. § 1.136(a). See 37 C.F.R. § 1.136(a)(1)(iv). AFFIRMED Copy with citationCopy as parenthetical citation