Ex Parte Wels et alDownload PDFPatent Trial and Appeal BoardJul 27, 201612558736 (P.T.A.B. Jul. 27, 2016) Copy Citation UNITED STA TES p A TENT AND TRADEMARK OFFICE APPLICATION NO. FILING DATE 12/558,736 09/14/2009 28524 7590 07/29/2016 SIEMENS CORPORATION INTELLECTUAL PROPERTY DEPARTMENT 3501 Quadrangle Blvd Ste 230 Orlando, FL 32817 FIRST NAMED INVENTOR Michael Weis UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O. Box 1450 Alexandria, Virginia 22313-1450 www .uspto.gov ATTORNEY DOCKET NO. CONFIRMATION NO. 2008Pl8365US01 7080 EXAMINER REYES, REGINALD R ART UNIT PAPER NUMBER 3686 NOTIFICATION DATE DELIVERY MODE 07/29/2016 ELECTRONIC Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. Notice of the Office communication was sent electronically on above-indicated "Notification Date" to the following e-mail address( es): ipdadmin.us@siemens.com PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte MICHAEL WELS, GUSTA VO HENRIQUE MONTEIRO DE BARROS CARNEIRO, MARTIN HUBER, DORIN COMANICIU, and YEFENG ZHENG Appeal2014-000769 Application 12/558,736 Technology Center 3600 Before MURRIEL E. CRAWFORD, MICHAEL W. KIM, and CYNTHIA L. MURPHY, Administrative Patent Judges. CRAWFORD, Administrative Patent Judge. DECISION ON APPEAL STATEMENT OF THE CASE Appellants seek our review under 35 U.S.C. § 134 of the Examiner's final decision rejecting claims 1-27. We have jurisdiction over the appeal under 35 U.S.C. § 6(b ). We REVERSE. Claim 1 is illustrative: 1. A method for segmenting a plurality of brain structures in a 3D magnetic resonance (MR) image, comprising: Appeal2014-000769 Application 12/558,736 detecting a meta-structure including center positions of each of said plurality of brain structures in the 3D MR image; and individually segmenting at least one of the plurality of brain structures using marginal space learning (MSL) constrained by the detected meta-structure. Appellants appeal the following rejections: 1. Claims 1, 2, 4, 6, 10-12, 15, 19, 20, 23, and 27 under 35 U.S.C. § 103(a) as unpatentable over Spence (US 2008/0298659 Al, pub. Dec. 4, 2008), Reiman (US 2005/0283054 Al, pub. Dec. 22, 2005), and Barbu (US 2010/0020208 Al, pub. Jan 28, 2010). 2. Claim 3 under 35 U.S.C. § 103(a) as unpatentable over Spence, Reiman, Barbu, and Cox (US 5,751,838, iss. May 12, 1998). 3. Claims 5, 7, 8, 16, 17, 24, and 25 under 35 U.S.C. § 103(a) as unpatentable over Spence, Reiman, Barbu, and Ikuma (US 2008/0306379 Al, pub. Dec. 11, 2008). 4. Claims 9, 18, and 26 under 35 U.S.C. § 103(a) as unpatentable over Spence, Reiman, Barbu, Ikuma, and Xu (US 2009/0316988 Al, pub. Dec. 24, 2009). ISSUE Did the Examiner err in rejecting the claims because Spence does not disclose detecting a meta-structure including center positions of each of said plurality of brain structures in the 3D MR image? 2 Appeal2014-000769 Application 12/558,736 FACTUAL FINDINGS Appellants' Specification states that embodiments of the present invention are directed to automated (sub-)cortical brain structure segmentation in 3D MR images [14]. The term "(sub-) cortical brain structure" refers to any sub-cortical and/or cortical brain structure such as the left and right caudate nucleus, hippocampus, globus pallidus, putamen and amydgala [ 15]. Figure 3 depicts several (sub-)cortical brain structures such as the left caudate nucleus 302, right caudate nucleus 303, left hippocampus 304, right hippocampus 305 etc. and their centers as depicted as 320 [28]. We find that Spence discloses that measurements were made available for volume elements or voxels [ 11]. Spence teaches that correlations among normalized voxel counts are large in neighboring voxels and decrease in magnitude until they become negligible after a critical distance. Based on this discovery, blocks of contiguous voxels may be defined within each of several structures within the deep brain so that the geometric centers of the blocks are not closer than the range at which voxel counts may be considered uncorrelated. ANALYSIS We agree with the Appellants that Spence discloses defining the centers of blocks of voxels within a brain structure, not detecting the center position of each of a plurality of brain structures. The blocks of Spence are comprised of several voxels within a brain structure and it is the center of these blocks which is defined, not the center of the brain structures themselves. 3 Appeal2014-000769 Application 12/558,736 In view of the foregoing, we will not sustain the Examiner's rejections of any of the claims, because each of the claims includes the step of detecting the center positions of each of a plurality of brain structures or a means for detecting the center positions of each of a plurality of brain structures. DECISION The decision of the Examiner is reversed. REVERSED 4 Copy with citationCopy as parenthetical citation