Ex Parte WebbDownload PDFBoard of Patent Appeals and InterferencesAug 17, 201010352418 (B.P.A.I. Aug. 17, 2010) Copy Citation UNITED STATES PATENT AND TRADEMARK OFFICE __________ BEFORE THE BOARD OF PATENT APPEALS AND INTERFERENCES __________ Ex parte DAVID M. WEBB __________ Appeal 2009-011137 Application 10/352,418 Technology Center 1600 __________ Before DONALD E. ADAMS, DEMETRA J. MILLS, and MELANIE L. McCOLLUM, Administrative Patent Judges. MILLS, Administrative Patent Judge. DECISION ON APPEAL1 This is an appeal under 35 U.S.C. § 134. The Examiner has rejected the claims for obviousness. We have jurisdiction under 35 U.S.C. § 6(b). 1 The two-month time period for filing an appeal or commencing a civil action, as recited in 37 C.F.R. § 1.304, or for filing a request for rehearing, as recited in 37 C.F.R. § 41.52, begins to run from the “MAIL DATE” (paper delivery mode) or the “NOTIFICATION DATE” (electronic delivery mode) shown on the PTOL-90A cover letter attached to this decision. Appeal 2009-011137 Application 10/352,418 2 STATEMENT OF THE CASE The following claim is representative and read as follows: 7. A method of selecting at least one soybean plant by marker assisted selection of a quantitative trait locus ("QTL") associated with soybean cyst nematode resistance, wherein said QTL is localized to a chromosomal interval on linkage group G above the marker pk69 and on or below the marker php02366, the sequence of marker php02366 having been deposited with the ATCC as Accession Number 69934, said method comprising testing at least one marker on said chromosomal interval for said QTL and selecting said soybean plant comprising said QTL. Cited References The Examiner relies on the following prior art references: Concibido et al., DNA Marker Analysis of Loci underlying Resistance to Soybean Cyst Nematode (Heterodera glycines Ichinohe), Crop Science 34, pp. 240-246 (1994). Keim et al., RFLP Mapping in Soybean: Association Between Marker Loci and Variation in Quantitative Traits, Genetics 126, pp. 735-742 (1990). Boutin et al., Soybean Genetics Newsletter, Vol. 19, pp. 123-127 (1992). Grounds of Rejection Claims 7, 8, 12 and 30 are rejected under 35 U.S.C. § 103(a) as being unpatentable over Concibido in view of Boutin, taken with the evidence of Keim. Appeal 2009-011137 Application 10/352,418 3 Discussion ISSUE The Examiner concludes that Concibido et al teach a method of selecting at least one soybean plant by marker assisted selection of a QTL associated with soybean cyst nematode resistance wherein said QTL is localized to a chromosomal region, said method comprising testing at least one marker (pB 32) on a chromosomal interval (chromosomal interval of linkage group A) (see, for example, page 137, last paragraph to page 138, lines 1-9) and selecting a soybean plant comprising said QTL (see page 138, Figure 1). Concibido et al do not teach a QTL localized to a chromosomal interval on linkage group G above the marker pk69 and on or below the marker php07366, Boutin et al teach RFLP marker pK69 and that it is associated with soybean cyst nematode resistance (see page 125, last paragraph). It would have been obvious to one of ordinary skill in the art to select other markers above and below marker pK69 to determine if other markers are associated with soybean cyst nematode resistance. (Ans. 4-5.) Appellant contends that “the use of markers above pk69 was not obvious…because pk69 was thought [in the prior art] to be at the top of linkage group G.” (App. Br. 5-6.) The issue is: Do the cited references render the claimed method prima facie obvious? PRINCIPLES OF LAW An invention “composed of several elements is not proved obvious merely by demonstrating that each of its elements was, independently, known in the prior art.” KSR Int’l Co. v. Teleflex Inc., 550 U.S. 398, 418 Appeal 2009-011137 Application 10/352,418 4 (2007). “Often, it will be necessary . . . to look to interrelated teachings of multiple [references] . . . and the background knowledge possessed by a person having ordinary skill in the art, all in order to determine whether there was an apparent reason to combine the known elements in the fashion claimed[.]” Id. at 418. “[T]his analysis should be made explicit” (id. at 418), and it “can be important to identify a reason that would have prompted a person of ordinary skill in the relevant field to combine the elements in the way the claimed new invention does” (id.). “[T]here must be some articulated reasoning with some rational underpinning to support the legal conclusion of obviousness.” In re Kahn, 441 F.3d 977, 988 (Fed. Cir. 2006). Moreover, “obviousness requires a suggestion of all limitations in a claim.” CFMT, Inc. v. Yieldup Int’l. Corp., 349 F.3d 1333, 1342 (Fed. Cir. 2003) (citing In re Royka, 490 F.2d 981, 985 (CCPA 1974)). When evaluating claims for obviousness, “the prior art as a whole must be considered. The teachings are to be viewed as they would have been viewed by one of ordinary skill.” In re Hedges, 783 F.2d 1038, 1041 (Fed. Cir. 1986). FINDINGS OF FACT The Examiner’s fact finding is set forth in the Answer at pages 3-6. ANALYSIS The Examiner concludes that one of ordinary skill in the art would have understood [from the prior art] that markers close to marker pk69 could also have been associated with soybean cyst nematode [SCN resistance] and therefore would have been motivated to search for them. Appeal 2009-011137 Application 10/352,418 5 (Ans. 8.) Appellant argues that the claims require testing at least one marker on the “chromosomal interval on the linkage group G above the marker pk69 and on or below the marker php02366.” (App. Br. 5.) The Appellant argues that “Boutin et al. teach marker pk69 on linkage group B, not linkage group G. (Id. at 7.) Appellants further argue that Keim generally teaches that some markers on linkage group B have duplicates on linkage group G. (Id.) Appellants conclude that each of the references “failed to recognize that linkage group G extended beyond pk69 and that a QTL for SCN resistance was located on linkage group G above pk69.” (Id. at 8.) The use of markers above pk69 was not obvious because pk69 was thought to be the top of linkage group G. (App. Br. 5-6.) We essentially agree with Appellant’s arguments as set forth in the Brief and Reply Brief. We find no evidence to support recognition in the prior art cited that linkage group G extended beyond pk69 and that a QTL for SCN resistance was located on linkage group G above pk69. Appeal 2009-011137 Application 10/352,418 6 CONCLUSION OF LAW The cited references do not support the Examiner’s obviousness rejection and do not disclose the claimed method. REVERSED alw PIONEER HI-BRED INTERNATIONAL, INC. 7250 N.W. 62ND AVENUE P.O. BOX 552 JOHNSTON, IA 50131-0552 Copy with citationCopy as parenthetical citation