Ex Parte Stuker et alDownload PDFPatent Trial and Appeal BoardFeb 6, 201712662815 (P.T.A.B. Feb. 6, 2017) Copy Citation United States Patent and Trademark Office UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O.Box 1450 Alexandria, Virginia 22313-1450 www.uspto.gov APPLICATION NO. FILING DATE FIRST NAMED INVENTOR ATTORNEY DOCKET NO. CONFIRMATION NO. 12/662,815 05/05/2010 Florian Stuker SP09862US 3917 20469 7590 02/06/2017 KOHLER SCHMID MOEBUS RUPPMANNSTRASSE 27 D-70565 STUTTGART, GERMANY EXAMINER BRUTUS, JOEL F ART UNIT PAPER NUMBER 3777 MAIL DATE DELIVERY MODE 02/06/2017 PAPER Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte FLORIAN STUKER, KATERINA DIKAIOU, CHRISTOF BALTES, and MARKUS RUDIN Appeal 2015-003161 Application 12/662,815 Technology Center 3700 Before WILLIAM A. CAPP, MICHAEL L. WOODS, and SEAN P. O’HANLON, Administrative Patent Judges. O’HANLON, Administrative Patent Judge. DECISION ON APPEAL STATEMENT OF THE CASE Florian Stuker et al. (Appellants)1 appeal under 35 U.S.C. § 134 from the Examiner’s decision rejecting claims 1, 3—11, 13—16, and 18.2 We have jurisdiction over this appeal under 35 U.S.C. § 6(b). We REVERSE. 1 According to Appellants, the real party in interest is the University of Zurich. App. Br. 3. 2 Claims 2, 12, and 17 are canceled. Id. at 5. Appeal 2015-003161 Application 12/662,815 SUMMARY OF INVENTION Appellants’ claimed invention is directed to “a dual modality imaging apparatus, comprising a magnetic resonance imaging . . . system and a fluorescence molecular tomography . . . system.” Spec. 1:11—13. Claim 1, reproduced below from pages 27—28 (Claims Appendix) of the Appeal Brief, is the sole independent claim and is representative of the claimed subject matter: 1. A dual modality imaging apparatus for investigating a sample located at a sample position, the apparatus comprising: a magnetic resonance imaging (=MRI) system, said magnetic resonance imaging system having a magnet with a room temperature bore within which the sample position is located, said room temperature bore having a longitudinal axis, said magnetic resonance imaging system further comprising a radio frequency coil having at least one window, said at least one window opening in a transverse direction, substantially perpendicular to said longitudinal axis of said room temperature bore, wherein said radio frequency coil is disposed within said room temperature bore and the sample is at least partially within said coil; and a fluorescence molecular tomography (=FMT) system having a mechanism for directing a light beam towards the sample position and a position-sensitive detector, said position- sensitive detector having electrical connections, said position- sensitive detector and said electrical connections being disposed within said bore and outside said radio frequency coil to detect fluorescence light from the sample, wherein at least part of the sample is imaged onto said position-sensitive detector, said mechanism for directing said light beam having a focusing device for focusing said light beam into a focal spot on the sample, a scanning device structured for continuously scanning said focal spot on the sample and a deflection mirror, said scanning device being disposed outside of said room temperature bore and said deflection mirror being disposed 2 Appeal 2015-003161 Application 12/662,815 inside said room temperature bore, wherein said mechanism for directing said light beam, said radio frequency coil and said position-sensitive detector are disposed, structured and dimensioned such that said light beam enters said room temperature bore substantially parallel to said longitudinal axis and is deflected by said deflection mirror in a substantially transverse direction to pass through said at least one window of said radio frequency coil and illuminate the sample, wherein fluorescence light emanating from the sample passes through said at least one window in said radio frequency coil and is incident on said position sensitive detector, the apparatus thereby being adapted for simultaneous measurement of MRI data and FMT data. REJECTION3 Claims 1, 3—11, 13—16, and 18 stand rejected under 35 U.S.C. § 103(a) as being unpatentable over Ntziachristos ’062 (US 2004/0015062 Al, pub. Jan. 22, 2004), Ntziachristos ’580 (US 2007/0274580 Al, pub. Nov. 29, 2007), Lindsay (US 5,750,989, iss. May 12, 1998), and Omori (US 5,066,915, iss. Nov. 19, 1991). ANALYSIS In establishing that a claim is obvious, all of the claim limitations must be taught or suggested by the prior art. See In re Royka, 490 F.2d 981 (CCPA 1974). Also, ‘“there must be some articulated reasoning with some rational underpinning to support the legal conclusion of obviousness.’” KSR Int’l Co. v. Teleflex Inc., 550 U.S. 398, 418 (2007) (quoting In re Kahn, 441 3 Although the Final Action purports that the claims are rejected over Ntziachristos ’062 “alone or in view of’ the other cited references (Final Act. 2 (emphasis added)), the Examiner does not present a rejection based on Ntziachristos ’062 alone. 3 Appeal 2015-003161 Application 12/662,815 F.3d 977, 988 (Fed. Cir. 2006)). Furthermore, it is not enough to simply show that the references disclose the claim limitations; in addition, ‘“it can be important to identify a reason that would have prompted a person of ordinary skill in the art to combine the elements as the new invention does.’” Transocean Offshore Deepwater Drilling, Inc. v. Maersk Contractors USA, Inc., 617 F.3d 1296, 1303 (Fed. Cir. 2010) (quoting KSR, 550 U.S. at 401) (emphasis added). Here, the Examiner determines that independent claim 1 is obvious in view of Ntziachristos ’062, Ntziachristos ’580, Lindsay, and Omori. Final Act. 2—6. The Examiner does not explain, however, and we cannot discern from the record, how each of the claim recitations are taught by the cited references or why one of ordinary skill in the art would combine the teachings of such references. For example, claim 1 recites, in relevant part: [a] magnetic resonance imaging system having a magnet with a room temperature bore ... a fluorescence molecular tomography . . . system having ... a scanning device . . . and a deflection mirror, said scanning device being disposed outside of said room temperature bore and said deflection mirror being disposed inside said room temperature bore. App. Br. 27—28 (Claims Appendix). It appears that the Examiner relies on the Background of the Invention section of Appellants’ Specification as setting forth that such a bored magnet is known. Final Act. 3. The Examiner, however, fails to explain how and why a skilled artisan would modify the device of Ntziachristos ’062 (which the Examiner identifies as the primary reference) to include such a magnet. See id. at 2—6. Having failed to positively identify a magnet having a bore therein, the Examiner nonetheless finds that Ntziachristos ’580 teaches an “optical 4 Appeal 2015-003161 Application 12/662,815 scanner [that] is adapted to move an optical element. . . into different positions corresponding to different positions of the focal spot using galvo- mirrors 156,” and asserts that, therefore, “the mechanism for directing the light, RF coil and the position sensitive detector are structured and dimensioned such that light beam enters the bore parallel to the longitudinal axis and [is] deflected by the mirror in a transverse direction.” Id. at 4. The Examiner reasons that it would have been obvious to a skilled artisan to use the optical scanner and mirror of Ntziachristos ’580 with the apparatus of Ntziachristos ’062 “to increase the system robustness” and “to selectively move the apparent light source to provide the plurality of light paths toward the specimen.” Id. at 5. We agree with Appellants that the Examiner has not established that the identified components are disposed as required by claim 1. See, e.g., App. Br. 19. More specifically, the Examiner has not identified a “scanning device being disposed outside of said room temperature bore” or a “deflection mirror being disposed inside said room temperature bore.” Moreover, as best that we can understand the Examiner’s rejection, it appears that the Examiner correlates optical scanner 150 of Ntziachristos ’580 as the recited scanning device and mirror 156 of Ntziachristos ’580 as the recited deflection mirror. Final Act. 4—5. However, Ntziachristos ’580 describes mirror 156 as being an internal component of optical scanner 150. Ntziachristos ’580 171, Fig. 3. Thus, it is further unclear to us how the Examiner proposes to dispose the optical scanner outside of a magnet bore while also disposing one component of the optical scanner (i.e., the mirror) inside the magnet bore. 5 Appeal 2015-003161 Application 12/662,815 “When a reference is complex . . the particular part relied on must be designated as nearly as practicable. The pertinence of each reference, if not apparent, must be clearly explained and each rejected claim specified.” 37 C.F.R. § 1.104(c)(2). The Examiner has not sufficiently done so here. Accordingly, we do not sustain the rejection of independent claim 1, nor of its dependent claims 3—11, 13—16, and 18. DECISION The Examiner’s decision to reject claims 1, 3—11, 13—16, and 18 is reversed. REVERSED 6 Copy with citationCopy as parenthetical citation