Ex Parte RE41859 et alDownload PDFPatent Trial and Appeal BoardMay 21, 201595001559 (P.T.A.B. May. 21, 2015) Copy Citation UNITED STATES PATENT AND TRADEMARK OFFICE UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O. Box 1450 Alexandria, Virginia 22313-1450 www.uspto.gov APPLICATION NO. FILING DATE FIRST NAMED INVENTOR ATTORNEY DOCKET NO. CONFIRMATION NO. 95/001,559 03/01/2011 RE41859 MHS-001RX 7427 51414 7590 05/21/2015 GOODWIN PROCTER LLP PATENT ADMINISTRATOR 53 STATE STREET EXCHANGE PLACE BOSTON, MA 02109-2881 EXAMINER GELLNER, JEFFREY L ART UNIT PAPER NUMBER 3993 MAIL DATE DELIVERY MODE 05/21/2015 PAPER Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE ____________________ BEFORE THE PATENT TRIAL AND APPEAL BOARD ____________________ COLDHARBOUR MARINE LIMITED Requester, Respondent v. MH SYSTEMS, INC.1 Patent Owner, Appellant ____________________ Appeal 2014-009650 Inter partes Reexamination Control 95/001,559 Patent US RE41,859 E2 Technology Center 3900 ____________________ Before STEVEN D.A. McCARTHY, DANIEL S. SONG and BRETT C. MARTIN, Administrative Patent Judges. SONG, Administrative Patent Judge. DECISION ON APPEAL 1 MH Systems, Inc. is the Patent Owner and the real party in interest (Appeal Brief of Patent Owner (hereinafter "App. Br.") 1). 2 Patent US RE41,859 E (hereinafter "the ’859 patent") issued October 26, 2010 to Husain et al., and is a reissue of U.S. Patent No. 6,761,123 issued July 13, 2004. Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 2 STATEMENT OF THE CASE Claims 2–6, 9, 10, 13–17, 19–31, 33–47 and 49–51 of the ’859 patent stand rejected and are the subject of the present appeal (Appeal Brief (hereinafter "App. Br.") 2). Claims 50 and 51 were added during the reexamination while claims 1, 7, 8, 11, 12, 18, 32 and 48 have been canceled (id.). The Patent Owner appeals under 35 U.S.C. §§ 134(b) and 315 from the Examiner's rejections with respect to all of the rejected claims (App. Br. 2). In addition to its Appeal Brief and Rebuttal Brief, the Patent Owner also relies on declaration of co-inventor Mr. Husain and declaration of Dr. Felbeck in support of patentability. The Requester relies on its Respondent Brief and declaration of Dr. Rau in support of the Examiner's rejections set forth in the Right of Appeal Notice (hereinafter "RAN").3 We have jurisdiction under 35 U.S.C. §§ 134(b) and 315. We AFFIRM. THE INVENTION The ’859 patent is directed to a method and system for killing aquatic nuisance species (hereinafter "ANS") in a ship's ballast water. Representative independent claim 2 reads as follows (col. 21, ll. 36–42; Claims App., claim 2 incorporating the limitations of cancelled parent claim 1): 2. [A method of killing aquatic nuisance species in ship's ballast water comprising: infusing carbon dioxide into the 3 The Examiner's Answer incorporates the RAN by reference. Hence we cite to the RAN herein. Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 3 ship's ballast water at a level effective to kill aquatic nuisance species by hypercapnia; while lowering oxygen in the same ship's ballast water to a level effective to kill aquatic nuisance species by hypoxia,] The method according to claim 1 wherein the infusing is with a gaseous mixture of ≥11 % carbon dioxide by molar volume, wherein the gaseous mixture comprises nitrogen, oxygen, and carbon dioxide.4 Independent claim 36 is directed to a system for reducing survival of ANS in a ship's ballast water (Claims App.). The record supports the following findings of fact (FF): 1. The specification of the ’859 patent: A. In discussing the known methods of addressing ANS, states: Known methods not mentioned in this [Glosten-Herbert- Hyde Marine (April 2002)] reference are hypoxia, carbonation, and their combination. In studies of 18 months duration on a coal/ore vessel (Tamburri et al. 2002), the ballast water dissolved O2 level was reduced and held to concentrations at or below 0.8 mg/l by bubbling essentially pure nitrogen. See Tamburri, M. N., Wasson[,] K., and Matsuda, M. (2002). Ballast water deoxygenation can prevent aquatic introductions while reducing ship corrosion. Biological Conservation. 103, 331-341. The experiments resulted in a treatment "that can dramatically reduce the 4 Material shown in brackets is taken from cancelled parent claim 1. The phrase, "while lowering oxygen in the same ship's ballast water to a level effective to kill aquatic nuisance species by hypoxia," was added to claim 1 by amendment during the reissue proceeding and is shown in italics in the ’859 patent. Struck out material appears in the preamble of claim 2. The phrase "wherein the gaseous mixture comprises nitrogen, oxygen, and carbon dioxide," shown underlined above, was added by amendment in this reexamination proceeding. Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 4 survivorship of most organisms found in the ballast water . . ." In extensive experiments with gas of varying percent CO2, N2 and O2 (McMahon, et al. 1995), the ". . . results indicate that CO2 injection may be an easily applied, cost- effective, environmentally acceptable molluscicide for mitigation and control [of] a raw water system macrofouling by Asian clams and zebra mussels". See McMahon, R. F., Matthews, M. A., Shaffer, L. R. and Johnson, P. D. (1995). Effects of elevated carbon dioxide concentrations on survivorship in zebra mussels (Dreissena polymorpha) and Asian clams (Corbicula fluminea). (Col. 2, ll. 23–43, emphasis added). B. In summarizing the known methods of addressing ANS, states: Except for ballast water exchange, essentially all treatment concepts involve the chemical change of the water to cause an environment lethal for ANS. The chemical changes described in Tamburri et al. (2002) and McMahon (1995) offer promising results, i.e., reduce the dissolved O2 in the one case, and carbonate and reduce the pH in the other case. See Tamburri, M. N., Wasson[,] K., and Matsuda, M. (2002), op cit. See also McMahon, R. F., Matthews, M. A., Shaffer, L. R. and Johnson, P. D. (1995), op cit. In both cases the process involves the exchange of gases, the extraction of the dissolved O2 and the introduction of CO2. (Col. 2, l. 65–col. 3, l. 9, emphasis added). C. In summarizing the disclosed invention, states that ANS is killed by: inducement of (1) hypercapnia (elevated concentration of dissolved CO2), (2) hypoxia (depressed concentration of dissolved O2), and (3) acidic pH level. The inert combustion Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 5 gases may be obtained, for example, from (i) a ship's inert gas generator (of the Holec, or equivalent types), and/or from (ii) ship's own flue gases. These gases are highly noxious, having CO2 significantly increased and O2 significantly depleted, from normal atmospheric levels. (Col. 5, ll. 1–14). D. States that the disclosed invention preferably uses the gaseous output of a standard shipboard inert gas generator preferably to enhance to >11% by volume and, preferably, to >15% by volume, the CO2 content of the gas used to carbonate the ballast water. The gaseous output of a standard shipboard inert gas generator "is commonly about 84% Nitrogen, 12–14% CO2 and 2% Oxygen, and/or as a ship's own flue gases." (Col. 5, ll. 35–48, emphasis added). THE REJECTIONS The Patent Owner appeals from the following rejections of various claims under 35 U.S.C. § 103(a) as being obvious over the noted combination of prior art (App. Br. 5)5: 1. Claims 13, 15, 24, and 26 over Ryan,6 McMahon,7 and Milwee.8 5 The Patent Owner summarizes the various Grounds of Rejection set forth in the RAN in its Appeal Brief, enumerating 16 issues in the appeal (App. Br. 5). The Requester accepts the Patent Owner's enumerated issues (Resp. Br. 1) and groups its rebuttal arguments accordingly (see generally, Resp. Br.). Thus, we address the present appeal based on the 16 issues enumerated by the Patent Owner and accepted by the Requester, referring to them as Rejections. Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 6 2. Claims 2, 47 and 49–51 over Watten9 and Milwee. 3. Claims 13, 15, 24 and 26 over Browning,10 McMahon, and Milwee. 4. Claims 13, 15, 24 and 26 over Greenman,11 McMahon, and Milwee. 5. Claims 2, 3, 9, 19, 20, 47 and 49–51 over Watten, Elzinga,12 and Milwee. 6. Claims 2, 4, 5, 10, 13, 15, 16, 19, 21, 22, 24, 26, 27, 47 and 49– 51 over Watten, McMahon, and Milwee. 7. Claims 13–15 and 24–26 over Tamburri,13 McMahon, and Milwee. 6 The Ballast Water Control Act: Hearings on H.R. 3360 Before the House Comm. on Merchant Marine And Fisheries, 103rd Cong., 73–79 (1993) (Testimony of George J. Ryan). 7 Robert F. McMahon et al, Effects of Elevated Carbon Dioxide Concentrations on Survivorship in Zebra Mussels (Dreissena polymorpha) and Asian Clams (Corbicula fluminea), PROCEEDINGS OF THE FIFTH INT’L ZEBRA MUSSEL & OTHER AQUATIC NUISANCE ORGANISMS CONF. 319–36 (Feb. 1995). 8 William I. Milwee, Jr., MODERN MARINE SALVAGE 465–69 (Cornell Maritime Press 1996) 9 US Patent No. 6,821,442 B1, issued Nov. 23, 2004, to Barnaby Jude Watten. 10 US Patent No. 5,932,112, issued Aug. 3, 1999, to Wilson J. Browning, Jr. 11 Debra Greenman et al., Port-Based Ballast-Water Treatment Systems: A Feasibility Study in the Port of Baltimore, 2(4) ANS DIGEST 38, 39 & 47 (Aug. 1998). 12 William J. Elzinga & Todd S. Butzlaff, Carbon Dioxide As A Narcotizing Pre-Treatment For Chemical Control Of Dreissena Polymorpha, PROCEEDINGS OF THE FOURTH INT’L ZEBRA MUSSEL CONFERENCE 45-59 (Mar. 1994). Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 7 8. Claims 13–17, 24–26, 36, 38, 41, 44–47 and 49 over Hunter,14 Elzinga, and Milwee. 9. Claims 13–17, 24–28, 36, 38, 41, 44–47 and 49 over Hunter, McMahon, and Milwee. 10. Claims 42 and 43 over Hunter,15 Milwee, Elzinga, and Furushima.16 11. Claims 42 and 43 over Hunter, McMahon, Milwee, and Furushima. 12. Claim 6 over Watten, McMahon, Milwee, and Hunter. 13. Claims 37, 39 and 40 over Hunter, McMahon, Milwee, and Watten. 14. Claims 17 and 23 over Watten, Milwee, McMahon, and Hunter. 15. Claims 29–31 and 33 over Greenman, Milwee, Tamburri, and Elzinga. 16. Claims 34 and 35 over Greenman, Milwee, Tamburri, Elzinga, and Hunter. 13 Mario N. Tamburri et al., Ballast Water Deoxygenation Can Prevent Aquatic Introductions While Reducing Ship Corrosion, 103 Biological Conservation 331-341 (2002). 14 US Patent Application No. 2002/0174814 A1, published Nov. 28, 2002, Henry Hunter. 15 The Patent Owner omits Hunter from the list of references cited in this ground of rejection (see RAN 82–83). This appears to be a typographical error. 16 Japanese Patent No. JP S60-222389 (A), published Nov. 6, 1985, to Furushima Nobuhiko. Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 8 PRINCIPLES OF LAW Arguments based on limitations not in the claims are unpersuasive. In re Self, 671 F.2d 1344, 1348 (CCPA 1982). In addition, non-obviousness cannot be established by attacking references individually where the rejection is based upon the teachings of a combination of references. In re Merck, 800 F.2d 1091, 1097 (Fed. Cir. 1986); In re Keller, 642 F.2d 413, 425 (CCPA 1981). A reference "must be considered for everything it teaches by way of technology and is not limited to the particular invention it is describing and attempting to protect." EWP Corp. v. Reliance Universal Inc., 755 F.2d 898, 907 (Fed. Cir. 1985). "The combination of familiar elements according to known methods is likely to be obvious when it does no more than yield predictable results." KSR Int'l Co. v. Teleflex Inc., 550 U.S. 398, 415–16 (2007). Explicit teaching is not required. Id. at 418–19 Moreover, "[c]ommon sense teaches . . . that familiar items may have obvious uses beyond their primary purposes, and in many cases a person of ordinary skill will be able to fit the teachings of multiple patents together like pieces of a puzzle." Id. at 420. In this regard, "[a] person of ordinary skill is also a person of ordinary creativity, not an automaton." Id. at 421. PRIOR ART FINDINGS OF FACT The record supports the following additional findings of fact (FF) by a preponderance of the evidence. Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 9 2. Watten: A. Discloses a method and apparatus for controlling aquatic invasive species in a ship's ballast water (Watten, Title; Abst.; col. 5, ll. 15–26; claims 2 and 10). B. States that oxygen deprivation, or hypoxia, is a known method for "shipboard treatment of ballast water" to kill zebra mussels, which are ANS (Watten, col. 3, ll. 20–22, 56–61). C. States that the disclosed invention "causes death of target species through continuous or intermittent exposure to supersaturated concentrations of carbon dioxide, air, combustion exhaust gas or a mixture of these gases when ΔP>0." (Watten, col. 8, ll. 5–8; accord col. 4, ll. 62–66). D. States "[i]t is understood that gas-liquid interfacial area can be created by a number of reactor-types, stages, and that the gas-liquid contacting can take place at pressures above, at or below local atmospheric pressure." (Watten, col. 10, ll. 25–28). E. States that when stack gas is transferred into water, acid may form and "a corresponding reduction in pH may then provide a third (concurrent) method of inducing mortality of zebra mussels or other exotic species through gas transfer, e.g., the pH threshold for survival of zebra mussel adults is 6.5 and for larvae 6.9." (Watten, col. 7, l. 61–col. 8, l. 4). Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 10 3. Elzinga: A. Describes the use of CO2 to control zebra mussels, including at levels lethal to the zebra mussel (Elzinga, Abst., Intro., pgs. 47, 50), and, thus, discloses hypercapnia. B. Discloses that dissolved O2 and pH values were also reduced with increasing CO2 levels, pH levels being depressed below 6.0, and as low as 5.2–5.3 (Elzinga, pg. 50). C. Teaches that low pH levels are probably attributable to formation of carbonic acid and that low pH interferes with ion exchange and calcium metabolism (Elzinga, pg. 50). 4. Milwee states: Inert gas systems fill the ullage space in cargo tanks with gases containing little or no oxygen, so the mixture in the tank remains outside the explosive range. . . . Exhaust gases from the ship's boiler or a separate inert gas generator provide the inert gas through a scrubbing system (figure 13- 4). Scrubbers and driers remove oxygen and water vapor until the gas theoretically contains only nitrogen (85 percent) and carbon dioxide (15 percent). (Milwee, pg. 467, emphasis added). 5. McMahon: A. Describes a study monitoring the effects of elevated CO2 concentrations on survivorship of zebra mussels and Asian clams, which are considered ANS (McMahon, pg. 319, Title, Abst.). Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 11 B. Describes continuously bubbling various gas mixtures under anoxia and hypercapnic normoxia conditions (McMahon, pg. 319, Abst.). C. States: These results indicate that CO2 injection may be an easily applied, cost-effective, environmentally acceptable molluscicide for mitigation and control of raw water system macrofouling by Asian clams and zebra mussels. In fossil fuel burning facilities, waste CO2 released from fuel combustion could be utilized to prevent mussel or clam fouling. (McMahon, pg. 320). D. States: Due to its ability to form a weak acid when dissolved in water (see Introduction), media bubbled with gases containing elevated concentrations of CO2 had a reduced pH. Over the course of the experiments the pH of media bubbled with 100% CO2 ranged between 5.3 and 6.5. The pH of media bubbled with gas mixtures with 5% CO2 ranged from 6.0 to 8.7 and with 10% CO2, from 6.2 to 7.5. When exposed to anoxia in media bubbled with 100% CO2 at 25°C (Pco2 = 760 torr) zebra mussels and Asian clam samples displayed considerably greater mortality rates than when exposed to anoxia induced by bubbling media with 100% N2 (Figure 1). (McMahon, pg. 324). E. Discloses providing CO2 into water as molluscicide using a microbubbling sparger system (McMahon, pg. 327). F. Teaches that "[i]f waste CO2 from combustion processes was captured and injected into raw water systems as a molluscicide, efficient control of bivalve macrofouling could be affected [sic, Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 12 effected] without the cost associated with purchase from a supplier." (McMahon, pg. 329). 6. Hunter: A. Discloses controlling pressure and content of ballast tank gases to kill organisms within ballast water wherein the ullage space gases are depressurized to a pressure less than atmosphere, and also inerted so that there is <4% O2 or preferably <2% O2, so that the O2 content of the ballast water is lowered to <1% PPM, and more preferably, <0.6% PPM (Hunter, Title; Abstract; Fig. 1). B. States: It does not matter for purposes of the present invention whether the (ii) inerted, oxygen-depleted, condition of the ullage space gases is realized by (1) extraction of oxygen, or by (2) addition of gases, primarily nitrogen, other than oxygen. Preferably flue gases, which are substantially devoid of oxygen and which are primarily nitrogen, are simply added to the ballast tank ullage space to cost effectively dilute the oxygen content of the ballast tank ullage space gases. (Hunter ¶ [0064]). C. States: In accordance with the present invention gaseous interchange between (i) gases––including oxygen––originally within the ballast water and (ii) inerted gases within the ullage space of the ballast water tank is very greatly accelerated. This interchange is so accelerated by maintaining (1) an underpressure in the ullage spaces. (Hunter ¶ [0072]; see also Fig. 1). Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 13 D. Discloses that ullage space gases are "depressurized to a pressure that is preferably less than a -2 p.s.i. threshold pressure level below nominal atmospheric pressure of 14.7 p.s.i. or to a pressure less than 12.7 p.s.i." (Hunter ¶ [0091]). E. States: Moreover, in accordance with the present invention there preferably also simultaneously transpires (2) bubbling inert gas(es) (primarily nitrogen) upwards through the ballast water. This bubbling is necessarily at a pressure greater than the (under)pressure of the ullage space plus the head of ballast water, but is still most preferably done at a pressure that is less than atmosphere. (Hunter ¶ [0073]; see also Fig. 1). F. States: The net result is that the ballast water becomes severely depleted of oxygen quite quickly, and on the order of hours; greatly stressing if not immediately (within the order of further minutes and hours) killing aerobic aquatic marine life (of all kinds) within the ballast water. Normally, and preferably, this oxygen-depleted condition of the ballast water is maintained for the substantial duration of the voyage of the ship. (Hunter ¶ [0076]). G. Discloses a "combustion gas generator" as a source for inert gas, which is "bubbled through ballast water" until solubility of the oxygen within the ballast is <1 PPM. (Hunter ¶¶ [0145]–[0147]). 7. Tamburri discloses a treatment that reduces the survivorship of most organisms, including ANS, found in ballast waters by purging oxygen from the ballast tanks to hypoxic levels by treating the ballast Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 14 water with nitrogen (Tamburri, Abst.; pg. 332, second column; pg. 335, second column). 8. Greenman discloses that a method for killing the organisms in the ballast water is to treat the water with "a ship's diesel exhaust." (Greenman, pg. 39). ANALYSIS We address the various arguments of the Patent Owner infra in an order that slightly differs from the order presented in the Patent Owner's briefs. Only those arguments actually made by the Patent Owner have been considered, and any arguments not made are deemed to be waived. See 37 C.F.R. § 41.67(c)(1)(vii). Rejection 5 Claims 2, 3, 9, 19, 20, 47, 49, 50 and 51 stand rejected as obvious over the combination of Watten, Elzinga and Milwee. In rejecting the claims, the Examiner incorporates by reference Ground 40 of the Office Action mailed April 11, 2011 (RAN 25), which states: Watten discloses a method of killing aquatic nuisance species in ship's ballast water (col. 1, lines 13–16; col. 5, lines 22–24) comprising: infusing carbon dioxide into the ship's ballast water (language of claims 1 and 2 of col. 15; col. 8, lines 5–11) at a level effective to kill aquatic nuisance species by hypercapnia (col. 8, lines 5–11); while lowering oxygen in the same ship's ballast water to a level effective to kill aquatic nuisance species by hypoxia (col. 8, lines 35–37). To the extent that Watten does not disclose infusing carbon dioxide to a level to cause both Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 15 hypercapnia and hypoxia, Elzinga discloses bubbling through water a gas mixture of carbon dioxide (bottom of page 49 to middle of page 50) which causes the water to be both hypercapnic (from "500 mg/l" of abstract and, for example, "290 mg/l" of top of page 50 of Elzinga) and hypoxic (Fig. 3 and "dissolved oxygen and pH values were successively reduced with increasing CO2 treatment levels" of middle of page 50) which results in killing of aquatic nuisance species (from "using carbon dioxide (CO2) a non-toxic treatment alternative for control of zebra mussel" of abstract). It would have been obvious to one of ordinary skill in the art at the time of the invention to modify the method of Watten by using the gas mixture of Elzinga to kill aquatic nuisance species so as to control growth of zebra mussels with a non-toxic treatment (see Elzinga at abstract). (Office Action mailed April 11, 2011, pg. 27). The Examiner's position is also that: To the extent Watten as modified by Elzinga does not disclose the gaseous mixture of ≥ 11 % carbon dioxide by molar volume and the gaseous mixture comprising nitrogen, oxygen, and carbon dioxide, Milwee discloses adding into the ballast/tank area a ship's boiler exhaust or gas generator's gas, after scrubbing and drying, that would have nitrogen (from "85 percent" of page 467), elevated CO2 levels (from "15%" of page 467 which is considered ≥ 11 % carbon dioxide by molar volume) and reduced O2 levels (from "remove oxygen" and "theoretically contains only nitrogen (85 percent) and carbon dioxide (15 percent)" of page 467). It would have been obvious to one of ordinary skill in the art at the time of the invention to further modify the method of Watten as modified by Elzinga by using the ship's boiler exhaust or a gas generator's gas as disclosed by Milwee so as to reduce the possibility of combustion on board ship when carrying flammable liquids (Milwee at pages 465–469) in addition to killing aquatic nuisance species. Use of the exhaust gas of Milwee in the method of Watten and Elzinga (with the gas mixture transferred Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 16 to the ballast water (Watten at col. 8, lines 8–11, and claims 1 and 2)) would inherently over time, or when in equilibrium, cause hypoxic and hypercapnic conditions in the ballast water which would consequently kill aquatic nuisance species. (RAN 25–26). Claims 2, 3, 9, 19 and 20 The Patent Owner argues that "Elzinga does not disclose the use of a gas mixture" and that the drop in dissolved oxygen disclosed in Elzinga "would not be effective to kill aquatic nuisance species by hypoxia." (App. Br. 23, citing Decl. of Felbeck ¶ 6). The Patent Owner also argues that "Watten and Milwee do not teach or suggest rendering ballast water hypoxic, and never state that a gaseous mixture of nitrogen, carbon dioxide, and oxygen should be used to render ballast water hypercapnic and hypoxic." (App. Br. 23). These arguments are unpersuasive mainly because they argue the references individually. In re Merck, 800 F.2d at 1097; In re Keller, 642 F.2d at 425. While Elzinga may not disclose the use of a gas mixture, both Watten and Milwee disclose use of gas mixtures. Watten teaches a method for treating ballast water for ANS using CO2, air, combustion exhaust gas, or mixtures thereof (FF 2A, 2C), and Elzinga also discloses use of CO2 at levels lethal to ANS and reduction of O2 (FF 3A, 3B). Although Elzinga also may not explicitly disclose hypoxia, Watten teaches that controlling ANS by hypoxia was known (FF 2B), and the Patent Owner also admitted in the Specification of the ’859 patent that hypoxia (as well as carbonation) was a known technique for controlling ANS (FF 1A, 1B). Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 17 As to the composition of the gas mixture, we observe that Watten teaches a mixture of CO2, air and combustion exhaust gas, or mixtures thereof (FF 2C) that would comprise nitrogen, carbon dioxide, and oxygen. The Patent Owner also argues that the gas of Milwee does not include oxygen because the disclosed gas mixture is 15% CO2 and 85% N2 (Rebuttal Br. 2–3). However, this argument not only ignores the teaching of Watten that a mixture of gases such as CO2, combustion exhaust gas, and air can be used that would include O2 (FF 2C), but also ignores Milwee's teaching that inert gas systems generate gases "containing little or no oxygen" and that the gas theoretically contains only nitrogen and carbon dioxide (FF 4), which indicates that some small amount of oxygen is likely present considering theoretical purity is difficult to attain in reality. Indeed, Milwee teaches that various hydrocarbons have different flammability requirements as to oxygen percentage, but does not disclose that zero oxygen is required to prevent an explosion, which is an objective of its disclosed invention (see Milwee, pg. 466). The Patent Owner further argues that Milwee does not use inert gas in treatment of ballast water and describes disadvantages of soot that is produced by overuse of inert gas, which can contaminate the cargo held in the cargo tanks (App. Br. 24). However, the Patent Owner ignores Watten's teaching to use CO2 and/or combustion exhaust gas, which are inert gases, in the ballast water as a treatment for ANS (FF 2A–2C). Moreover, the existence of a disadvantage does not establish non-obviousness. See Medichem, S.A. v. Rolabo, S.L., 437 F.3d 1157, 1165 (Fed. Cir. 2006) ("a given course of action often has simultaneous advantages and disadvantages, Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 18 and this does not necessarily obviate motivation to combine."). In the case at hand, the inert gas is being provided to the ballast water to be released back into the ocean instead of some product that is to be sold. The record indicates that ANS carried within the ballast water is a significant problem, but there is little indication that such gaseous treatment of ANS poses a significant problem when the treated water is released back into the ocean. The Patent Owner argues that the conclusion "that it would have been obvious to use inert gas to treat ballast water cannot be reconciled with the long-standing coexistence of inert gas systems on ships and the previously unresolved problem with aquatic nuisance species in ballast water." (App. Br. 24). However, as further discussed infra relative to secondary considerations, we disagree that killing of ANS in ballast tanks is an unsolved problem considering the explicit teachings of Watten to use inert gas, such as combustion exhaust gas, for this very purpose (FF 2A–2C). In addition, the prior art of record also indicates that a person of ordinary skill knew that inert gas might be obtained from the ship's exhaust and/or the onboard inert gas generator (FF 4), to any extent that these gases materially differ. While beyond its primary purpose explicitly disclosed in Milwee of providing inert gas to cargo tanks to prevent explosion, use of an inert gas generator to provide inert gas to the ballast tank would have been obvious to a person of ordinary skill in view of Watten (FF 2A–2C) and considering such a person possesses ordinary creativity. KSR, 550 U.S. at 420–421. Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 19 Claim 47 The Patent Owner refers to the same arguments proffered relative to claims 2, 3, 9, 19 and 20 (App. Br. 24), which are unpersuasive for the reasons already discussed. The Patent Owner also argues that "[n]one of Watten, Elzinga, and Milwee teach infusing carbon dioxide into ship's ballast water that is maintained under atmospheric pressure or less" and that "Watten relies on high pressure to supersaturate the ballast water" so that it does not teach killing ANS "at pressure less than atmospheric pressure." (App. Br. 24). This argument is unpersuasive because, inter alia, it is based on limitations not in the claim. In re Self, 671 F.2d 1344, 1348 (CCPA 1982). Claim 47 does not require that the ballast water be maintained "at pressure less than atmospheric pressure" as argued, but instead, recites that the ballast water be maintained "under atmospheric pressure or less." It cannot be reasonably disputed that maintaining ballast water under atmospheric pressure was a known practice. Claim 49 The Patent Owner refers to the same arguments proffered relative to claims 2, 3, 9, 19, 20 and 47 (App. Br. 24), which are unpersuasive for the reasons already discussed. The Patent Owner also argues that the references fail to teach killing aquatic nuisance species "by hypercapnia in combination with reduced, acidic, pH." (App. Br. 25). However, Watten discloses that in addition to hypercapnia, reduction in pH is a "third (concurrent) method of inducing mortality" of ANS (FF 2E; Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 20 RAN 32). In addition, Elzinga clearly discloses controlling ANS by increasing CO2, which also lowers pH values, thus interfering with ion exchange and calcium metabolism of ANS (FF 3A–3C; RAN 33). Accordingly, we agree with the Examiner that over time, the combination of the prior art would "cause hypercapnic, hypoxic, and reduced (acidic) pH conditions in the ballast water which would consequently kill aquatic nuisance species." (RAN 33). We also agree with the Requester that it would have been obvious to one of ordinary skill in the art to "infuse a gaseous mixture with an elevated CO2 concentration (e.g., exhaust gas from a ship's engine) into ballast water until the CO2 concentration is high enough to kill ANS by hypercapnia and/or the pH of the ballast water is itself low enough to kill ANS." (Resp. Br. 5–6; see also Decl. of Rau ¶ 6). In the above regard, we also note that the claims do not identify the particular specie(s) of ANS to be killed via hypercapnia and reduced pH, different species having differing tolerances to various environmental conditions. Claim 50 and 51 The Patent Owner arguments as to these claims are substantively the same as those already discussed supra. The Patent Owner also argues that the Office has provided no motivation for including 2–4% mole percent oxygen as required by the claims (App. Br. 25). The Examiner's position is that such percentage of oxygen would have been obvious "depending on the type of exhaust or gas generator used." (RAN 94). We agree with the Examiner. We also observe that the specification of the ’859 patent states that the gaseous output of a standard shipboard inert gas generator has 2% Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 21 oxygen (FF 1D). We further observe that the Patent Owner's argument is based on an inert gas content described as merely "theoretical" (FF 4). Thus, this limitation would be satisfied upon using a standard shipboard inert gas generator, such as that of Milwee, as a source for inert gas and would have been obvious based on knowledge of the output of standard shipboard inert gas generators. Rejection 6 Claims 2, 4, 5, 10, 13, 15, 16, 19, 21, 22, 24, 26, 27, 47 and 49–51 stand rejected as obvious over the combination of Watten, McMahon, and Milwee. The issues pertaining to this rejection are similar to those of Rejection 5 already discussed except that McMahon is relied upon instead of Elzinga. In rejecting these claims, the Examiner incorporates by reference Ground 52 of the Office Action mailed April 11, 2011 (RAN 34). Correspondingly, the position of the Examiner is that: To the extent that Watten does not disclose infusing carbon dioxide to a level to cause both hypercapnia and hypoxia, McMahon discloses bubbling through water a gas mixture of carbon dioxide (100%) which causes the water to be both hypercapnic (from "solubility of CO2 at saturation at 25°C (as in media bubbled with 100% CO2) is 1,430 mg 1-1 or 750 ml 1- 1" and Table 3 of bottom of page 327 of McMahon where 1430 mg/1 is 1430 ppm) and hypoxic (abstract, top of page 323, Fig. 1 for solid circles and triangles) which results in killing of aquatic nuisance species (Fig. 1). It would have been obvious to one of ordinary skill in the art at the time of the invention to modify the method of Watten by using the gas mixture of McMahon to kill aquatic nuisance species so as to control the macrofouling spread of both zebra mussels and Asian clams (see McMahon at middle of page 321). Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 22 (Office Action mailed April 11, 2011, pg. 34). Claims 2 and 4 The Patent Owner presents arguments substantively similar to those presented with respect to Rejection 5 (App. Br. 25–26), which have already been addressed supra. As to McMahon, the Patent Owner argues that: While McMahon does teach mixtures of nitrogen, oxygen, and carbon dioxide, those mixtures are "normoxic," and would not lower oxygen to a level effective to kill aquatic nuisance species by hypoxia. In contrast to McMahon's discussions of anoxia or hypercapnic normoxia, McMahon never teaches or suggests inducing hypoxia, and never suggests using a gaseous mixture comprising nitrogen, carbon dioxide, and oxygen to do so. (App. Br. 26). However, the Patent Owner again argues the references separately. Gaseous mixtures of nitrogen, oxygen, and carbon dioxide are disclosed in Watten and Milwee (FF 2A, 2C, 4) as well as McMahon. In addition, both Watten and the admission of the Patent Owner establish that controlling ANS through hypoxia was a known technique (FF 2A, 2B, 1A, 1B). We also observe that McMahon also discloses gas mixtures under hypercapnic anoxia condition as well as hypercapnic normoxia condition (FF 5B). Correspondingly, it would have been obvious to a person of ordinary skill in the art to consider and use a gas mixture that is between anoxia and normoxia conditions to control ANS through hypoxia, which was a known technique (FF 2A, 2B, 1A, 1B). KSR, 550 U.S. at 420–421. Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 23 Claim 5 The Patent Owner refers to the same arguments proffered relative to claims 2 and 4 (App. Br. 26), which are unpersuasive for reasons already discussed. The Patent Owner also argues that although claim 5 requires bubbling of the gaseous mixture "through ballast water that is under less than atmospheric pressure," Watten discloses "pressures greater than atmospheric to supersaturate the water," so that the use of claimed method would be contrary to principle of operation disclosed in Watten (App. Br. 26). The position of the Examiner is that this limitation is satisfied by Watten's disclosure that "the gas-liquid contacting can take place at pressures above, at or below local atmospheric pressure" (RAN 36; FF 2D). Indeed, while Watten does disclose treatment of ballast water at pressures greater than atmospheric pressure, as discussed in further detail infra with respect to claim 16, Watten nonetheless also discloses that the treatment wherein the gas-liquid contact occurs at below atmospheric pressure (FF 2D) to thereby satisfy the limitation at issue. Claim 10 The Patent Owner refers to the unpersuasive arguments proffered relative to claims 2 and 4 (App. Br. 27). The Patent Owner also argues that the combination of Watten, McMahon, and Milwee fails to suggest CO2 concentration in the ballast water of ≥ 20ppm (App. Br. 27). However, claim 10 does not recite CO2 concentration of ≥ 20ppm, but instead recites that "the infusing transpires by bubbling the gaseous mixture through the Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 24 ballast water." (Claims App.). As the Examiner finds (RAN 37), McMahon discloses bubbling of the gases and a microbubbling sparger system (FF 5B, 5D, 5E). Claims 13 and 15 The Patent Owner again refers to the unpersuasive arguments proffered relative to claims 2 and 4 (App. Br. 27). The Patent Owner also argues that the combination of Watten, McMahon, and Milwee fails to suggest mixture of nitrogen, oxygen and CO2, wherein O2 is ≤ 4%, the only mixture in McMahon having all three gases is normoxic, and the gas of Milwee does not have oxygen (App. Br. 27). However, these arguments have already been addressed supra and found unpersuasive. Claim 16 The Patent Owner refers to the unpersuasive arguments proffered relative to claims 5, 13 and 15 (App. Br. 27). The Patent Owner also argues that while claim 16 requires bubbling through the ballast water that is under less than atmospheric pressure (App. Br. 27), in Watten, the killing of ANS occurs at pressures above atmospheric pressure (App. Br. 28, citing Watten, Abstract). Again, the position of the Examiner is that this limitation is satisfied by Watten's disclosure that "the gas-liquid contacting can take place at pressures above, at or below local atmospheric pressure" (RAN 39; FF 2D). According to the Patent Owner, the "gas-liquid contacting" referenced in Watten "takes place before 'the raw water is exposed at positive gage Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 25 pressures to gas enriched with CO2 thereby allowing for high required dissolved gas tensions,'" and "[a]ny optional pretreatment below atmospheric pressure cannot change the fact that killing of aquatic species in Watten occurs later and only above atmospheric pressure." (App. Br. 28, citing Watten, Abstract). We disagree. The pertinent portion of Watten states as follows: The CO2 pretreatment absorber 28 accelerates gas absorption by exposing the water to a gas with a partial pressure of CO2 that exceeds dissolved carbon dioxide tensions in the incoming raw water and by establishing gas-liquid interfacial area needed for gas transfer. For example, exposing water to 50% CO2 gas mixture (XCO2 =0.5, Equation 2) can increase the carbon dioxide saturation concentration (C*, Equation 2) by a factor of 2860. It is understood that gas-liquid interfacial area can be created by a number of reactor-types, stages, and that the gas- liquid contacting can take place at pressures above, at or below local atmospheric pressure. Following the pretreatment absorber 28, raw water is forced by a pump 12 through the gas absorber 18. In the gas absorber 18, the raw water is exposed at positive gage pressures to gas enriched with CO2 thereby allowing for high required dissolved gas tensions. (Watten, col. 10, ll. 16–33). Thus, the term "gas-liquid interfacial area" is referenced in the context of accelerating CO2 absorption and increasing the carbon dioxide saturation concentration. Watten then teaches that the gas-liquid interfacial area can be created so that the gas-liquid contact occurs "at pressures above, at or below local atmospheric pressure." Id. Thus, while Watten does disclose treatment at pressures greater than atmospheric pressure, it also suggests that CO2 can be added to water that is under less than atmospheric pressure. Moreover, Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 26 while the Patent Owner argues that this provision of CO2 via closed conduit 30 is in the context of a pretreatment, we fail to see a distinction because the steps disclosed in Watten are all part of the disclosed method for treating ballast water to control ANS, and the claims do not prohibit multiple steps. We also do not share the view that "killing of aquatic species in Watten occurs later and only above atmospheric pressure" as asserted (App. Br. 28). If the water is treated so that ANS cannot survive, it is immaterial that the specific treatment is characterized as being part of an earlier stage of treatment versus a later stage of treatment. Watten discloses treating the water with CO2 to increase its saturation concentration by a very large factor and teaches that this can occur at pressures below atmospheric pressure. Claims 19, 21 and 22 The Patent Owner refers to, or submits, unpersuasive arguments that are substantively the same as those already addressed (App. Br. 28–29). In response to the Examiner's finding that "adding carbon dioxide to a ship's ballast water will concomitantly lower pH." (RAN 40, citing Dec. of Rau ¶ 4), the Patent Owner also argues that it is not necessarily true that adding carbon dioxide to a ship's ballast water will lower pH because "presence of calcium compounds or other buffering agents in the ballast water may counteract the effect of an increase in carbonic acid." (App. Br. 28). We find this argument is also unpersuasive because both Watten (FF 2E) and McMahon (FF 5D) disclose reduction in pH. The argument is also unpersuasive because it is speculative as to the presence of calcium compounds or other unspecified buffering agents, and their potential effects. Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 27 The Patent Owner further argues that McMahon discloses that pH may not be reduced below neutrality, and that this may minimize corrosion rates (App. Br. 29) which is a desirable outcome. However, this argument based on McMahon individually is unpersuasive. Watten clearly discloses the addition of carbon dioxide to control ANS in a ship's ballast water even while recognizing the resultant pH reduction (FF 2A, 2C–2E). A person of ordinary skill in the art would know that CO2 levels sufficient to result in killing ANS by hypercapnia will concomitantly lower pH as found by the Examiner (RAN 40; FF 5D; see also FF 2E). Finally, to any extent that the reduction in pH may increase corrosion rates, mere existence of a potential disadvantage does not establish non-obviousness. See Medichem, 437 F.3d at 1165.17 Claims 24, 26 and 27 The Patent Owner refers to the unpersuasive arguments proffered relative to claims 2, 4, 19, 21 and 22 (App. Br. 29). The Patent Owner also argues that these claims require substitution of gases and that the gas mixture contains ≤ 4% O2, but Watten teaches killing via supersaturated concentration of CO2 or gas bubble disease (App. Br. 29) and that the combination to substitute gases changes Watten's principle of operation (App. Br. 29–30). However, while the Patent Owner argues Watten separately, as found by the Examiner (RAN 43), McMahon discloses substitution of gases by 17 Indeed, Tamburri, which is of record but not relied upon for this rejection, also establishes that deoxygenation can reduce ship corrosion (see Tamburri, Title; see also FF 1A). Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 28 preponderance of the evidence, considering that it does not increase pressure to supersaturate the ballast water. Indeed, substitution of gases has been admitted to be known and disclosed in McMahon in the specification of the ’859 patent, which states that prior art processes including that of McMahon involve "the exchange of gases, the extraction of the dissolved O2 and the introduction of CO2." (FF 1B). As to the percentage of oxygen, we agree with the Examiner (RAN 43) that this limitation is disclosed by Milwee for the reasons already discussed supra. Furthermore, the underlying principle of operation of Watten and McMahon is to kill ANS by changing the balance of the dissolved gas in the water so that ANS cannot survive in the changed environment. Moreover, as discussed supra, Watten specifically teaches provision of gas "at pressures above, at or below local atmospheric pressure." (FF 2D). Thus, we do not agree that the principle of operation by the combination suggested. Claims 47 and 49–51 The Patent Owner refers to the unpersuasive arguments proffered relative to claims 2 and 4 and submits other arguments substantively the same as those already found unpersuasive supra (App. Br. 30–32). Rejection 9 Claims 13–17, 24–28, 36, 38, 41, 44–47 and 49 stand rejected as obvious over the combination of Hunter, McMahon and Milwee. In rejecting the claims, the Examiner incorporates by reference Grounds 103 and 107 of the Office Action mailed April 11, 2011 (RAN 68), which states: Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 29 Hunter discloses a method of killing aquatic nuisance species in ship's ballast water (abstract) comprising: infusing gas into the ship's ballast water (from "primary nitrogen" from paragraph [0073]) while lowering oxygen in the same ship's ballast water to a level effective to kill aquatic nuisance species by hypoxia (abstract). (Office Action mailed April 11, 2011, pg. 61). In addition, "[t]o the extent that Hunter does not disclose infusing carbon dioxide to a level to cause both hypercapnia and hypoxia," the Examiner sets forth findings with respect to McMahon noted supra relative to Rejection 6 (id.). The Examiner further sets forth the same findings with respect to Milwee, noted supra relative to Rejection 5, "[t]o the extent Hunter as modified by McMahon does not disclose the carbon dioxide gaseous mixture also containing nitrogen and ≤4% oxygen." (RAN 69). Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 30 Claims 13-17 These claims require infusion of a gaseous mixture containing carbon dioxide, nitrogen, and oxygen, in which oxygen is <4%. The Patent Owner argues that "Hunter does not teach a gaseous mixture comprising carbon dioxide, nitrogen, and oxygen" and that while McMahon does teach "hypercapnic normoxic" gaseous mixture, neither Hunter nor McMahon teaches using a gaseous mixture of nitrogen, oxygen, and carbon dioxide to kill ANS both by hypercapnia and by hypoxia (App. Br. 39). The Patent Owner also argues that substituting McMahon's hypercapnic normoxic mixtures "would defeat the principle of operation of Hunter, since Hunter operates by depleting oxygen in ballast waste to kill aquatic nuisance species." (App. Br. 39). The Patent Owner's arguments are unpersuasive. Hunter discloses killing of ANS within ballast water by the addition of inert gas mixture so that there is <4% O2 (FF 6A, 6F). Hunter also discloses that flue gases that are "substantially devoid of oxygen and which are primarily nitrogen" may be used (FF 6A, 6B), the qualifiers "substantially" indicating that some oxygen is present in the flue gases by preponderance of the evidence. Hunter also teaches that a "combustion gas generator" may be used as a source for the inert gas (FF 6G). In addition, as already discussed, Milwee disclose a gas mixture having oxygen <4%. The evidence of record also indicates that inert gas generated by such onboard gas generator includes about 84% nitrogen, 12–14% CO2, and 2% oxygen (FF 1D). While Hunter does not appear to explicitly disclose killing ANS by hypercapnia, McMahon clearly does (FF 5A, 5C, 5E). The method of these Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 31 claims merely recites an obvious combination of the two known methods of killing ANS, namely, by hypoxia (FF 6A, 6F) and hypercapnia (FF 5A, 5C, 5E), to yield a predictable result. KSR, 550 U.S. at 415–16. The remaining arguments as to these claims are substantively the same as those addressed and found unpersuasive supra. Claims 24–28 The Patent Owner relies on the unpersuasive arguments submitted with respect to claims 13–17, as well as arguments already considered supra and found unpersuasive (App. Br. 40). Claims 36, 41, 44 and 47 As to these claims, the Patent Owner argues that combining Hunter and McMahon does not result in the recited mixture of carbon dioxide, nitrogen and oxygen (App. Br. 41). We are not persuaded. In addition to the discussion supra with respect to Hunter that teaches use of an onboard combustion gas generator as the source of the inert gas (FF 6G) and McMahon that suggests waste CO2 from combustion processes as the inert gas (FF 5D, 5F), the Patent Owner ignores Milwee's teachings as to inert gas systems (FF 4) and its own admission that standard shipboard inert gas generators output a mixture of carbon dioxide, nitrogen, and oxygen (FF 1D). The remaining arguments as to these claims are substantively the same as those already addressed and found unpersuasive. Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 32 Claim 38 The Patent Owner refers to the unpersuasive arguments submitted with respect to claims 36, 41, 44 and 47, and further argues that the references "fail to suggest that an inert gas generator could be used to generate the pure carbon dioxide of McMahon." (App. Br. 42). However, this is not the proper inquiry and the Patent Owner does not take into account what the collective teachings of the prior art would have suggested to one of ordinary skill in the art. See In re Keller, 642 F.2d at 425; EWP, 755 F.2d at 907. The Patent Owner ignores the combined teachings of Hunter and Milwee as already discussed supra and McMahon's teaching of killing ANS by elevating levels of CO2, which may be obtained from fuel combustion processes (FF 5A, 5C, 5F). The proper inquiry is whether "flue gases" and "combustion gas generator" disclosed in Hunter (FF 6B, 6G) and inert gas disclosed in Milwee (FF 4) satisfy the claim recitations pertaining to the gas composition. Claim 45 The Patent Owner refers to the unpersuasive arguments with respect to claim 38 (App. 42). While not disputing the Examiner's finding that the prior art combination discloses the recited amount and constituents of gases recited in claim 45 (RAN 78), the Patent Owner argues that the prior art fails to establish that an inert gas generator could generate a gas to render the ballast water hypoxic, hypercapnic, and acidic to the levels recited (App. Br. 42–43). However, we observe that claim 45 specifically recites that the gas is "produced by the inert gas generator." (Claims App.). It is not apparent Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 33 where in the specification the ’859 patent discloses an inert gas generator that differs from the disclosed "standard shipboard inert gas generator" (FF 1D) or discloses further processing of the generated gas mixture. Thus, by preponderance of the evidence, it follows that the gas from the disclosed standard inert gas generator is sufficient to render the ballast water hypoxic, hypercapnic, and acidic to the levels recited. Correspondingly, it likewise follows by preponderance of the evidence that the recited levels are satisfied by the disclosure of the combustion gas generator in Hunter (FF 6G) and/or inert gas system in Milwee (FF 4). Furthermore, we also observe that attaining the recited ballast water conditions also depends on the amount of water treated, as well as the duration of the treatment, both of which are not recited in the claim, or otherwise limited by the specification of the ’859 patent. Correspondingly, the claim limitations at issue are satisfied by the disclosures in the prior art in view of the admissions in the specification of the ’859 patent and/or is an obvious optimization of result effective variables based on the particular inert gas generator, amount of ballast water involved, and the duration of the treatment. See In re Boesch, 617 F.2d 272, 276 (CCPA 1980) (discovery of an optimum value of a result effective variable is ordinarily within the skill of the art); In re Aller, 220 F.2d 454, 456 (CCPA 1955). Claim 46 The Patent Owner argues that while claim 46 requires the inert gas to be delivered at a rate sufficient to establish equilibrium in the ballast water within a period less than one-half the normal voyage duration minus the time Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 34 for ANS to die to 90% level, the prior art does not "establish that a gas produced by the inert gas generator could ever achieve the required effects, regardless of the rate of delivery." (App. Br. 43). However, analysis similar to that of claim 45 discussed above applies here as well, and we agree with the Examiner (RAN 79) that it would have been obvious to have the rate of gas delivery so as to attain equilibrium within the time frame and lethality recited. In this respect, we further observe that both McMahon and Hunter disclose bubbling of the gas (FF 5B, 5D, 5E, 6E, 6G), and Hunter further discloses depressurizing the ullage space gasses to a pressure less than atmosphere (FF 6A, 6C–6D). Both of these techniques are described in the specification of the ’859 patent as enhancing deoxygenation as the gases are exchanged in the water (see, e.g., the ’859 patent, col. 7, ll. 20–27; col. 15, ll. 65–66). Hunter explicitly describes that when its system is used, in which the gas is bubbled and ullage space is depressurized, "the ballast water becomes severely depleted of oxygen quite quickly, and on the order of hours; greatly stressing if not immediately (within the order of further minutes and hours) killing aerobic aquatic marine life (of all kinds) within the ballast water." (FF 6F). Correspondingly, we do not agree that claim 46 presents nonobvious subject matter. Claim 49 The Patent Owner's arguments with respect to claim 49 (App. Br. 43– 44) are substantively the same as those already discussed and, thus, are unpersuasive. Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 35 Rejections 11–14 Regarding Rejections 11–14, the Patent Owner refers to previous arguments with respect to Rejections 9 and 6 in support of patentability of the rejected claims (App. Br. 44–47). These arguments are unpersuasive for the reasons discussed supra. Rejection 15 Claims 29–31 and 33 stand rejected as obvious over the combination of Greenman, Milwee, Tamburri and Elzinga. As to claim 29, the Examiner finds: Greenman discloses a method of reducing survival of aquatic nuisance species in ship's ballast water (from "ideal treatment system would remove or kill all organisms either before the ballast water enters the ballast tank or before the vessel enter the port of designation" of middle of col. 1, page 39) comprising permeating the equilibrium a gaseous mixture consisting essentially of ≥84% nitrogen, ≥11 % carbon dioxide and ≤ 4% oxygen through ship's ballast water (from "treating water with . . . a ship's diesel exhaust to kill organisms" of middle of col. 1, page 39, in that this is comparable to "ship's own flue gases" of Husain at col. 5, lines 42-48). (RAN 90). The Examiner also alternatively relies on Milwee in the manner set forth supra with respect to other grounds of rejection and further states: To the extent that Greenman and Milwee do not disclose these concentrations, Tamburri discloses the ballast water being hypoxic to ≤ 1 ppm oxygen (from "≤0.2 mg/l" of page 334 of Tamburri); Elzinga discloses water being hypercapnic to ≥ 20 ppm carbon dioxide (from "toxic effects at concentrations of 500 mg/l" of abstract of Elzinga with 500 mg/l equal to 500 ppm), and acidic to pH ≤ 7 (from Fig. 3 of Elzinga). Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 36 It would have been obvious to one of ordinary skill in the art at the time of the invention to modify the method of Greenman by using the ship's boiler exhaust or a gas generator's gas as disclosed by Milwee so as to reduce the possibility of combustion on board ship when carrying flammable liquids (Milwee at pages 465-469) in addition to killing aquatic nuisance species. Use of the exhaust or gas generator's gas of Milwee in the method of Greenman would inherently over time, or when in equilibrium, cause hypercapnic, hypoxic, and acidic conditions in the ballast water which would consequently kill aquatic nuisance species. Further, permeating the ballast of Greenman with the gaseous mixture of Greenman, Milwee, Tamburri and Elzinga would kill aquatic nuisance species so as to control growth of zebra mussels with a non-toxic treatment (see Elzinga at abstract). (RAN 90–91). Claim 29 As to claim 29, the Patent Owner argues that Greenman does not disclose any details of the manner in which a ship's diesel exhaust is used to treat water so as to kill ANS, such as pressure conditions, pre-treatment requirements, etc. (App. Br. 47). However, the Patent Owner does not establish that such specific details are required to practice the technique disclosed in Greenman or that lack of such details renders the disclosure therein false or inoperative to kill ANS. For example, the Patent Owner does not assert, much less establish, that killing of ANS via ship's diesel exhaust requires the specific pressure conditions, pre-treatment, etc. Greenman teaches what it teaches, that is, treating ballast water with a ship's diesel exhaust is a method for killing organisms in the ballast water (FF 8). Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 37 The Patent Owner also argues that the references relied upon, and its own specification in the ’859 patent, do not disclose the composition of the ship's diesel gas recited in the claims (App. Br. 47–48). While that may be true, the specification in the ’859 patent itself established functional equivalence between the gaseous output of a standard shipboard inert gas generator and a ship's flue gases (FF 1D). Thus, in view of the admitted functional equivalence, a prima facie case of equivalence as to the composition of those gases has been established. The Patent Owner does not argue, much less establish through persuasive evidence, that a ship's flue gases do not disclose the recited composition. Furthermore, the Patent Owner's argument that Milwee's gas does not include oxygen, and other arguments (App. Br. 48–49) have been previously discussed and found unpersuasive. Claim 30 The Patent Owner relies on unpersuasive arguments submitted relative to claim 29 and presents arguments (App. Br. 50) that have been previously discussed and found unpersuasive as well. Claim 31 The Patent Owner relies on unpersuasive arguments submitted relative to claim 30 and further argues that while claim 31 requires CO2 concentration within the range from 14% to 11% and O2 concentration in the range of 2% to 4%, Milwee merely discloses CO2 concentration of 15% and no reference discloses the range of O2 (App. Br. 50–51). However, similar Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 38 considerations as those set forth supra relative to arguments regarding claim 45 in Rejection 9 is also applicable here. The Patent Owner ignores the teachings of Greenman that a ship's diesel exhaust can be used to kill organisms in the ballast water (FF 8), Milwee's teachings that ship's exhaust gases have N2, CO2 and O2 for the reasons already discussed (FF 4), and its own statements as to the functional equivalence between a ship's flue gases and the gaseous output of a standard shipboard inert gas generator, which outputs a mixture of CO2, N2 and O2 having the gas concentrations within the recited ranges of claim 31 (FF 1D). Claim 33 The Patent Owner relies on unpersuasive arguments submitted relative to claim 29 and submits unpersuasive arguments (App. Br. 51) that have already been substantively addressed. Rejection 16 Claims 34 and 35 stand rejected as obvious over the combination of Greenman, Milwee, Tamburri, Elzinga and Hunter. The Patent Owner again relies on unpersuasive arguments submitted relative to claim 29 and already substantively addressed (App. Br. 51–52). Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 39 Secondary Considerations Citing to the Declaration of Husain for support, the Patent Owner asserts that although the problems associated with addressing ANS were recognized in the art for a long time, this long-felt need was not satisfied until the present invention (App. Br. 9–11). The declarant Mr. Husain is a named co-inventor of the ’859 patent and is the "President, CEO, and sole stockholder of MH Systems, Inc. (the assignee of the [’859] patent)" (Decl. of Husain ¶ 1), and thus, Mr. Husain has a financial and controlling interest in the ’859 patent. The Patent Owner cites to Ryan (1993), Nonindigenous Aquatic Nuisance Prevention and Control Act of 1990, and National Invasive Species Act (1996) to support the contention that prior to the claimed invention, "the long-felt need for a solution to the problem of aquatic nuisance species in ballast water" was not solved (App. Br. 10–11; Decl. of Husain ¶ 10). However, the prior art of record indicates that solutions similar to that of the claimed invention had been developed to address the problem of ANS in ballast water. In particular, prior art references Watten (FF 2A–2C), Hunter (FF 6A–6G), Tamburri (FF 7) and Greenman (FF 8), all published subsequent to the National Invasive Species Act (1996), describe various solutions to the ANS problem in which an inert gas, such as combustion exhaust gas (FF 2C, 6B, 8) or gas from a gas generator (FF 6G), is provided to the ballast water. These prior art references teach solutions that, while not identical, are similar to that of the claimed invention, and support the conclusion that the problem of ANS had been solved prior to the invention disclosed in the ’859 patent. The declarant does not address the prior art of Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 40 record beyond those arguments set forth in its briefs, which have been addressed supra. The Patent Owner also asserts that the invention has been copied by Requester Coldharbour (App. Br. 11), relying on Coldharbour's webpage which states: As the inert gas diffuses into the ballast water through the GLD, Oxygen is stripped from the water whilst the elevated level of [CO2] in the inert gas temporarily reduces the pH of the water. This simultaneously induces hypoxia and a condition known as hypercapnia in marine life. These conditions are fatal to many marine organisms. (printout of Coldharbour webpage, Exhibit N of App. Br.) In this regard, the Patent Owner notes that Requester Coldharbour previously worked closely with the Patent Owner as evidenced by the article "Ballast water treatment transatlantic alliance," Tanker Operator (July 25, 2008). (App. Br. 12; see also Decl. of Husain ¶ 9). Indeed, this article establishes a marketing relationship between the Patent Owner and Coldharbour in Europe and other selected markets. However, the above evidence is inadequate to demonstrate nonobviousness through copying. In this regard, the Patent Owner does not identify what product or method practiced by Coldharbour copies the invention of the ’859 patent; and how such a product or method satisfies all of the limitations of a claim of the ’859 patent. Mere establishment of a prior marketing relationship, and reference to simultaneous inducement of hypoxia and hypercapnia, do not adequately establish that the product of Coldharbour, or method practiced thereby, meets all the limitations of a claim, or that copying occurred. "Not every competing product that Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 41 arguably falls within the scope of a patent is evidence of copying." Iron Grip Barbell Co. Inc. v. USA Sports, Inc., 392 F.3d 1317, 1325 (Fed. Cir. 2004). [Copying] may be demonstrated either through internal documents, see Akamai Techs., Inc. v. Cable & Wireless Internet Servs., Inc., 344 F.3d 1186, 1196-97 (Fed. Cir. 2003); direct evidence such as disassembling a patented prototype, photographing its features, and using the photograph as a blueprint to build a virtually identical replica, see Advanced Display Sys., Inc. v. Kent State Univ., 212 F.3d 1272, 1285 (Fed. Cir. 2000); or access to, and substantial similarity to, the patented product (as opposed to the patent), Cable Elec. Prods., Inc. v. Genmark, Inc., 770 F.2d 1015, 1027 (Fed. Cir. 1985), overruled on other grounds by, Midwest Indus., Inc. v. Karavan Trailers, Inc., 175 F.3d 1356, 1359 (Fed. Cir. 1999) (en banc). Iron Grip Barbell Co. Inc. v. USA Sports, Inc., 392 F.3d 1317, 1325 (Fed. Cir. 2004). Moreover, the mere fact of copying is not necessarily dispositive of nonobviousness. See Cable Electric Prods., Inc. v. Genmark, Inc., 770 F.2d 1015, 1028 (Fed. Cir. 1985) ("[C]opying could have occurred out of a general lack of concern for patent property . . . ."). There is insufficient evidence to persuasively establish that copying occurred in the present case. Thus, in our assessment, the statements of declarant Husain as to lack of solutions and copying are conclusory assertions from an interested party, which are inadequately supported by persuasive objective evidence and analysis. Correspondingly, like the Examiner (RAN 97–99), we are not persuaded that the Patent Owner has sufficiently demonstrated nonobviousness of the claimed invention through secondary considerations. Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 42 Remaining Rejections The Examiner also rejected various claims in Rejections 1–4, 7, 8 and 10. However, Rejections 5, 6, 9, 11–16 have been affirmed supra, and thus, all of the claims on appeal remain rejected. Correspondingly, Rejections 1– 4, 7, 8 and 10 are moot and we decline to reach the same. ORDERS 1. Rejections 5, 6, 9, 11–16 are AFFIRMED, and thus, the rejection of claims 2–6, 9, 10, 13–17, 19–31, 33–47 and 49–51 as being obvious in view of the prior art is AFFIRMED. 2. The Examiner's rejection of all of the claims having been affirmed, the remaining Rejections 1–4, 7, 8 and 10 are moot. Requests for extensions of time in this inter partes reexamination proceeding are governed by 37 C.F.R. § 1.956. In the event neither party files a request for rehearing within the time provided in 37 C.F.R. § 41.79, and this decision becomes final and appealable under 37 C.F.R. § 41.81, a party seeking judicial review must timely serve notice on the Director of the United States Patent and Trademark Office. See 37 C.F.R. §§ 90.1 and 1.983. AFFIRMED peb Appeal 2014-009650 Reexamination Control 95/001,559 Patent US RE41,859 E 43 Third Party Requester: GOODWIN PROCTER LLP Patent Administrator 53 State Street Exchange Place Boston, MA 02109-2881 Patent Owner: Bruce Owens MYERS BIGEL SIBLEY & SAJOVEC, P.A. 4140 Parklake Avenue, Suite 600 Raleigh, NC 27612 Copy with citationCopy as parenthetical citation