Ex Parte PouloDownload PDFPatent Trial and Appeal BoardSep 29, 201612748782 (P.T.A.B. Sep. 29, 2016) Copy Citation UNITED STA TES p A TENT AND TRADEMARK OFFICE APPLICATION NO. FILING DATE FIRST NAMED INVENTOR 121748,782 03/29/2010 Louis Poulo 23266 7590 10/03/2016 DRIGGS, HOGG, DAUGHERTY & DEL ZOPPO CO,, LPA 38500 CHARDON ROAD DEPT. DLBH WILLOUGBY HILLS, OH 44094 UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O. Box 1450 Alexandria, Virginia 22313-1450 www .uspto.gov ATTORNEY DOCKET NO. ANA1056-US (ANA106893) CONFIRMATION NO. 5924 EXAMINER HENKEL, DANIELLE B ART UNIT PAPER NUMBER 1799 NOTIFICATION DATE DELIVERY MODE 10/03/2016 ELECTRONIC Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. Notice of the Office communication was sent electronically on above-indicated "Notification Date" to the following e-mail address( es): usptocommunications@driggslaw.com carole@driggslaw.com mwheeler@driggslaw.com PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PA TENT TRIAL AND APPEAL BOARD Ex parte LOUIS POUL01 Appeal2015-003820 Application 12/748,782 Technology Center 1700 Before MARK NAGUMO, JAMES C. HOUSEL, and GEORGE C. BEST, Administrative Patent Judges. NAGUMO, Administrative Patent Judge. DECISION ON APPEAL Louis Poulo ("Poulo") timely appeals under 35 U.S.C. § 134(a) from the Final Rejection2 of claims 1-20, which are all of the pending claims. We have jurisdiction. 35 U.S.C. § 6. We reverse the rejection over prior art and we enter a new ground of rejection of all claims as indefinite under 35 U.S.C. § 112 ,-i 2 pursuant to our authority under 37 C.F.R. §41.50(b).3 1 The real party in interest is identified as Analogic Corporation. (Appeal Brief, filed 18 August 2014 ("Br."), 2.) 2 Office action mailed 17 March 2014 ("Final Rejection"; cited as "FR"). Appeal2015-003820 Application 12/748,782 A. Introduction4 OPINION The subject matter on appeal relates to temperature control of a sample carried by a micro channel device. (Spec. 1, 11. 3--4.) Micro channel devices are said to be used, inter alia, in biochips, labs-on-a-chip, and inkjet printheads (id. at 11. 1. 8), where temperature control may be desired for "processing, analysis, and/or other purposes" (id. at 11. 9-10). Standard methods of controlling the temperature of a micro channel device, such as using a Peltier thermoelectric heat pump, are said to require good mechanical/thermal contact between the Peltier device and the micro channel device, with concomitant accurate and precise mechanical alignment and pressure. (Id. at 11. 12-22.) Increase in the size of the micro channel device, non-uniformity of heat transfer, and increased thermal mass, which requires increased power to implement thermal cycling, are said to result. (Id. at 11. 22-26.) Poulo seeks patent protection for a heating/cooling device that controls the temperature of the micro channel device by placing it in a chamber and bringing a heating/cooling fluid into thermal contact with the micro channel device. (Id. at 3, 11. 1820.) An embodiment of the claimed micro channel device processing apparatus is illustrated in Figure 1, reproduced below. 3 We refer to the pre-AIA version of the statute because this application was filed before 16 March 2013. 4 Application 12/748,782, Micro channel device temperature control, filed 29 March 2010. We refer to the '"782 Specification," which we cite as "Spec." 2 Appeal2015-003820 Application 12/748,782 {Figure 1 is shown below} PROCESSING APP/IRA TUS !02~ ____ \ !QC' (f--tiifr-RO ------1 -------------- _J-,, MICRO : : CHANNEL DEVICE : ~------------- -1./ CHANNEL OEllICE ' 1---------------.J ...:::~----~----~--- ....... HEA TI NG/COOU NG CHAMBER !04 FLUJO CONTROL SYSTEM 114 {Figure 1 shows a block diagram of a processing apparatus} IOO Micro channel device processing apparatus 100 receives (in this case the entirety of) micro channel device 102 in heating/cooling chamber 104.5 Heating/cooling fluid 200 circulates through heating/cooling chamber 104, as shown in Figure 3, below. {Figure 3 is shown below.} { •.• !!!!!!!!!!!!!!!!!: ~ i:::::::::::::::::::::~:::::::::::::::::i .. :· {Figure 3: circulation of heating/ coo ling fluid 200 through chamber 104} 5 Throughout this Opinion, for clarity, we present labels to elements in figures in bold font, regardless of their presentation in the original document. 3 Appeal2015-003820 Application 12/748,782 In the words of the '782 Specification, [i]n FIGURE 3, the fluid control system 108 (FIGURE 1) moves the fluid 200 into the chamber 104 and around the micro channel device 102, and out of the chamber 104 through the same side as the fluid is moved into the chamber 104. The fluid 200 leaving the chamber 104 may be expelled from the processing apparatus 100 or re-circulated, via the fluid control system 108, back into the chamber 104. (Spec. 5, 11. 1-14.) Claim 1 is representative and reads: A micro channel device processing apparatus, comprising: a heating/cooling chamber configured to receive at least a sub-portion of a micro channel device, wherein the heating/cooling chamber includes multiple sides; an inlet and an outlet, wherein the inlet and outlet are located on a same side of the heating/cooling chamber and are not part of the heating/cooling chamber; and a fluid control system that controls a flow of a heating/cooling fluid in the chamber, wherein the fluid control system controls the temperature of the micro channel device by introducing and circulating a fluid in the heating/cooling chamber relative to the micro channel device such that the fluid enters and exits via a same side of the multiple sides. (Claims App., Br. 9-1 O; some indentation, paragraphing, and emphasis added.) 4 Appeal2015-003820 Application 12/748,782 The Examiner maintains the following ground of rejection6 : Claims 1-20 stand rejected under 35 U.S.C. § 103(a) in view of the combined teachings ofYoder7 and Mahjoob.8 B. Discussion Findings of fact throughout this Opinion are supported by a preponderance of the evidence of record. Poulo urges (id. at 5, 11. 8-10) that Yoder seeks circulation of a heating/cooling fluid that allows "near-instantaneous temperature changes to be uniformly applied to a large number of samples." (Yoder 10 [0119].) Moreover, in Poulo's view, Yoder, at [0121], teaches that "non-uniform fluid flow across the case is undesirable since it results in uneven temperature gradients across a case." (Br. 5, 11. 10-12.) Poulo urges further that Mahjoob teaches that the fluid flow geometry shown in Fig. 7a (not reproduced here) results in reduced heat transfer at the comers of the conductive plate due to the velocity distribution, and that the larger non- uniformity in temperature results in a longer cycling time. (Br. 6, 11. 1-9, citing Mahjoob, section 5.3 at 2119-20.) On this basis, Poulo urges that the Examiner erred in concluding that it would have been obvious to use the heating/cooling fluid circulation geometry described by Mahjoob in Fig. 7a with the thermal cycling head described by Yoder in Figure 19. (Br. 6, 11. 10-15.) 6 Examiner's Answer mailed 12 December 2014 ("Ans."). 7 Karl Yoder et al., Thermal cycler for microjluidic array assays, U.S. Patent Application Publication 2006/0094108 Al (2006). 8 Shadi Mahjoob et al., Rapid microfluidic thermal cycler for polymerase chain reaction nucleic acid amplification, 51 Int'l J. Heat and Mass Transfer 2109 (2008). 5 Appeal2015-003820 Application 12/748,782 The weight of the evidence supports Poulo. The Examiner has not directed our attention to any evidence of an advantage taught by Mahjoob arising from the dis-favored flow geometry described in Fig. 7a that might have prompted the artisan to adopt that dis-favored geometry in the device described in Figure 19 of Yoder, which is reproduced below. {Yoder Figure 19 is shown below} 1·······t><}«««·rJi~~'"1r' «««<{>--..:;;_--·•----·t,.-'Y,,,J·'"""'""~~ ... ;. ~ ... ":~::-i'~"- l"""""' i '\ ; . .. , ·'<;,:\\~\; ll i l '\., ___ ,/' \ : '" •' '" . 1 PUMP ! : «r i ' ~ t /··- l ";.} l i ~5 ---+--.. . : : ~ ~-.-.,w.•o•l,,.,.._..,"~ ~ ~ '<> ~ ! '~ ...... ~·1"' ~ I! Lf>Copy with citationCopy as parenthetical citation