Ex Parte Megens et alDownload PDFPatent Trial and Appeal BoardAug 9, 201613393857 (P.T.A.B. Aug. 9, 2016) Copy Citation UNITED STA TES p A TENT AND TRADEMARK OFFICE APPLICATION NO. FILING DATE FIRST NAMED INVENTOR 13/393,857 03/02/2012 Mischa Me gens 24737 7590 08/11/2016 PHILIPS INTELLECTUAL PROPERTY & STANDARDS 465 Columbus A venue Suite 340 Valhalla, NY 10595 UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O. Box 1450 Alexandria, Virginia 22313-1450 www .uspto.gov ATTORNEY DOCKET NO. CONFIRMATION NO. 2009P01218WOUS 6173 EXAMINER TURCHEN, ROCHELLE DEANNA ART UNIT PAPER NUMBER 3777 NOTIFICATION DATE DELIVERY MODE 08/11/2016 ELECTRONIC Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. Notice of the Office communication was sent electronically on above-indicated "Notification Date" to the following e-mail address( es): marianne.fox@philips.com debbie.henn@philips.com patti. demichele@Philips.com PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte MISCHA MEGENS and JAN SUIJVER Appeal2014-007832 1 Application 13/393,857 Technology Center 3700 Before DONALD E. ADAMS, JEFFREY N. FREDMAN, and TIMOTHY G. MAJORS, Administrative Patent Judges. PERCURIAM DECISION ON APPEAL This is an appeal2 under 35 U.S.C. § 134 involving claims to a medical ultrasound device with temperature detection at the distal end. The Examiner rejected the claims on the grounds of provisional obviousness-type double-patenting, failing to comply with the written description requirement, anticipation, and obviousness. We have jurisdiction under 35 U.S.C. § 6(b ). We affirm the double patenting and written description rejections, reverse the anticipation rejection and enter new grounds of rejection for obviousness. 1 This Appeal is related to Appeal No. 2014-006831 (Application No. 13/393,244) that affirmed the rejection of record entered June 23, 2016. 2 Appellants identify the Real Party in Interest as Koninklijke Philips N.V. (see App. Br. 3). Appeal2014-007832 Application 13/393,857 Statement of the Case Background Appellants' invention "relates to a medical ultrasound device, such as a probe or catheter-based device. In particular the invention relates to such devices capable of detecting the temperature at the distal end of the device" (Spec. 1 :2--4 ). The Claims Claims 1-13 are on appeal. Independent claim 1 is representative and reads as follows (emphasis added): 1. A medical ultrasound device comprising: an elongated body (3) having a proximal end (90), a distal end (10), a distal end region (1) and a length axis (9) along the elongation; one or more ultrasound transducers ( 4) for generating acoustic radiation, the one or more ultrasound transducers being positioned in the distal end region, inside the elongated body; a transmission element ( 5) positioned in the radiation path of the acoustic radiation, wherein the transmission element is substantially transparent to acoustic radiation; and a controller unit (91) operatively connected to the ultrasound transducer to detect the acoustic path length through the transmission element and to determine a temperature at the distal end from the detected acoustic path length. The Issues A. The Examiner provisionally rejected claims 1-11 under the judicially created doctrine of obviousness-type double patenting as being unpatentable over claims 1-15 of Barley et al., US 13/393,244, filed Feb. 29, 2012 ("Barley") (Ans. 2-3). 2 Appeal2014-007832 Application 13/393,857 B. The Examiner rejected claims 12 and 13 under 35 U.S.C. § 112, first paragraph, as failing to comply with the written description requirement (Ans. 3--4). C. The Examiner rejected claims 1, 2, 4, 11, and 12 under 35 U.S.C. § 102(b) as being anticipated by Lang3 (Ans. 4--5). D. The Examiner rejected claims 3 and 7-9 under 35 U.S.C. § 103(a) as obvious over Lang and Sliwa4 (Ans. 5-6). E. The Examiner rejected claims 5, 10, and 13 under 35 U.S.C. § 103(a) as obvious over Lang and Mast5 (Ans. 6-7). F. The Examiner rejected claim 6 under 35 U.S.C. § 103(a) as obvious over Lang and Bames6 (Ans. 7). A. Provisional obviousness-type double patenting over claims 1-15 of Barley The Examiner determines that "[a]lthough the conflicting claims are not identical, they are not patentably distinct from each other because claims 1-11 of the present application disclose all of the structural limitations of claim 1-15 of the co-pending application" (Ans. 3). Appellants contend that the inventive force detection concept of Barley is derived from "the acoustic path length between the ultrasound transducer and the transmission element" and the inventive temperature detection concept of Megens is derived from ... "the acoustic path length through the transmission element", which is neither 3 Lang et al., US 2003/0078498 Al, published Apr. 24, 2003. 4 Sliwa et al., US 2010/0168572 Al, published July 1, 2010. 5 Mast et al., US 2004/0127791 Al, published July 1, 2004. 6 Barnes et al., US 2004/0236223 Al, published Nov. 25, 2004. 3 Appeal2014-007832 Application 13/393,857 identical to nor equivalent to "the acoustic path length between the ultrasound transducer and the transmission element". (Reply Br. 12.) We find that the Examiner has the better position. We agree with the Examiner that "[i]t was well known in the ultrasound medical field of endeavor, at the time of the invention to detect contact force and temperature of ultrasound to provide optimized use of an ultrasound system during a procedure" (Ans. 9--10). Accordingly, because the claims recite the same structures differing only in the obvious detection of temperature rather than contact force, we agree with the Examiner that the claims are not patentably distinct and affirm the provisional obviousness-type double patenting rejection. B. 35 USC§ 112, First Paragraph, New Matter The issue with respect to this rejection is: Does the evidence of record support the Examiner's conclusion that the phrase "wherein the transmission element and the one or more ultrasound transducers are mounted so that an acoustic path length through the transmission element varies with the temperature at the distal end" represents new matter? Findings of Fact 1. The Specification teaches that: Due to the ablative process, the temperature of the ablation electrode and the tissue increases and as a result, the acoustical path length through the transparent ablation electrode increases too. By monitoring the positioning of the two peaks, the acoustic path length can be monitored. From analysis of the monitored data, it is possible to obtain sub-pixel resolution. The main physical effect which gives rise to the changes in the acoustical path length is the change of the speed of sound in dependence 4 Appeal2014-007832 Application 13/393,857 upon the temperature changes. It can be mentioned that the material expansion of either the electrode or the transmission element over the relevant temperature ranges is nearly negligible. As the temperature rises, the speed of sound decreases, resulting in an increase[d] acoustical path length, which is seen as an increase in the distance 43, 44 between the two peaks. (Spec. 7:22-8:7.) 2. The Specification teaches that In a situation of use, the temperature at the distal end may be determined based on a look-up table or a functional relationship between a parameter related to the acoustic path length and the temperature at the distal end, e.g. as deduced from a measurement as presented in FIG. 7. Look-up table, functional relationships etc. may be stored by and computed in the controller unit or a computing unit in or connected to the controller unit. (Id. at 9: 1-5.) Principles of Law [I]t is the specification itself that must demonstrate possession [of the invention]. And while the description requirement does not demand any particular form of disclosure ... or that the specification recite the claimed invention in haec verba, a description that merely renders the invention obvious does not satisfy the requirement. Ariad Pharms., Inc. v. Eli Lilly and Co., 598 F.3d 1336, 1352 (Fed. Cir. 2010). Analysis The Examiner determines that"[ c ]laims 12 and 13 disclose 'wherein the transmission element and the one or more ultrasound transducers are mounted so that an acoustic path length through the transmission element 5 Appeal2014-007832 Application 13/393,857 varies with the temperature at the distal end.' There is no support for this limitation i[ n] the written description" (Ans. 4). Appellants contend that "the subject matter recited by dependent claims 12 and 13 is supported by the written description of FIGS. 1, and 4--7 of Megens. See, Megens at page 6, line 3 to page 9, line 5" (App. Br. 11; see also Reply Br. 13). More particularly, Appellants argue that the Specification teaches In FIG. 4, it can be seen that the two peaks (maxima indicated by reference numerals 40, 41) are observed. . . . In the area between the two peaks, the ultrasound radiation is propagating inside the transmission element. Due to the ablative process, the temperature of the ablation electrode and the tissue increases and as a result, the acoustical path length through the transparent ablation electrode increases too. . . . The main physical effect which gives rise to the changes in the acoustical path length is the change of the speed of sound in dependence upon the temperature changes. . . . As the temperature rises, the speed of sound decreases, resulting in an increases acoustical path length, \'l1hich is seen as an increase in the distance 43, 44 bet\'l/een the two peaks." (App. Br. 12-13; see also Reply Br. 14--15). We find that the Examiner has the better position. As Appellants point out, the Specification teaches that "f djue to the ablative process, the temperature of the ablation electrode and the tissue increases and as a result, the acoustical path length through the transparent ablation electrode increases too" and that "[ t ]he main physical effect which gives rise to the changes in the acoustical path length is the change of the speed of sound in dependence upon the temperature changes" (FF 1 (emphasis added)). The Specification also teaches that "the material expansion of either the electrode or the transmission element over the relevant temperature ranges is nearly 6 Appeal2014-007832 Application 13/393,857 negligible" (FF 1) and that "the temperature at the distal end may be determined based on a look-up table" (FF 2 (emphasis added)). Therefore, we agree with the Examiner that the disclosures that "the main physical effect which gives rise to the changes in the acoustical path length is the change of the speed of sound in dependence upon temperature changes," and "as the temperature rises, the speed of sound decreases, resulting in an increased acoustical path length, which is seen as an increase in the distance 43, 44 between the two peaks" are directed inherent properties of the acoustic path length based on temperature changes, not that the specific configuration of figs. 1 and 4--7 in which the transmission element and the one or more ultrasound transducers are mounted so that the acoustic path length to vary with the temperature at the distal end. (Ans. 11-12; see also FF 1-2.) We recognize, but are not persuaded by, Appellants' contention that "[t ]he implication of the scope of the aforementioned limitation of dependent claims 12 and 13 is a transmission element and ultrasound transducer( s) may be mounted so that an acoustic path length through the transmission element does not vary with a temperature at the distal end" (Reply Br. 13) because the claims do not recite "does not vary." C. 35 USC§ 102(b) over Lang Appellants contend that Lang "fails to describe ... 'a controller unit operatively connected to the ultrasound transducer to detect the acoustic path length through the transmission element and to determine a temperature at the distal end from the detected acoustic path length' as recited in independent claims 1and11" (App. Br. 14). 7 Appeal2014-007832 Application 13/393,857 We agree with Appellants. Claim 1 does not recite "capable of' determining a temperature, instead, claim 1 recites "operatively connected ... to determine a temperature at the distal end from the detected acoustic path length." Accordingly, we conclude that claim 1 requires a controller unit that determines a temperature at the distal end from the detected acoustic path length. The Examiner does not identify a teaching in Lang where a controller determines a temperature. We, therefore, reverse the anticipation rejection over Lang. D.-F. 35 US.C. § 103(a) Because the Examiner's reasoning relies upon Lang as an anticipation reference of independent claims 1 and 11, we will reverse the obviousness rejections. However, because Mast teaches the elements missing from Lang, we will enter New Grounds of Rejection. New Grounds of Rejection We reject claims 1, 2, 4, 5, and 10-13 under 35 U.S.C. § 103(a) as being obvious over Lang and Mast. We reject claims 3 and 7-9 under 35 U.S.C. § 103(a) as obvious over Lang, Mast, and Sliwa. We reject claim 6 under 35 U.S.C. § 103(a) as obvious over Lang, Mast, and Barnes. Findings of Fact 3. Lang teaches "a hand-held ultra-sonic system that includes a transducer for transmitting and receiving ultra-sonic waves for ... tissue 8 Appeal2014-007832 Application 13/393,857 measurement, an electronic operating unit to control and process ultrasonic wave generation and detection, and a display" (Lang i-f 95). 4. Lang's Figure 1 is reproduced below: I I ............ '.i\t ..... -) ... Figure 1 "shows an object plane relative to an ultrasonic probe 2 with an acoustic coupling gel 3 between the probe 2 and the object plane and having a connection 1 to signal processing unit" (Lang i-f 18). 5. Lang teaches that the computational unit is capable of determining the shortest reflective distance when two or more ultra-sonic sources are employed at different transmission angles. The computational unit may also be used for controlling the ultra-sonic generator or source, for defining or varying the firing rate and pulse repetition rate (as well as other parameters related to the ultra-sonic generator or source), for measuring the reflected signal, for image reconstruction in B-scan mode and for filtering and thresholding of the ultra-sonic signal. (Lang i-f 40). 6. Lang teaches an "adjustment sets the threshold of signal amplitudes that are permitted to enter a data storage, processing or display system" (Lang i-f 72). 9 Appeal2014-007832 Application 13/393,857 7. Mast teaches that [ s ]ince the travel time of an ultrasonic echo depends on both the path length (which is changed by any thermal expansion) and sound speed (which depends on temperature), temperature changes in tissue being treated cause measurable alterations to echo travel times. By estimation and further processing of these travel times, temperature rises can be approximately mapped. This arrangement is highly desirable, since heating effects of ultrasound treatment may be measured using inexpensive, portable, and unobtrusive ultrasound apparatus. For configurations in which therapy and monitoring are performed using the same ultrasound probe, this approach is particularly desirable, since a temperature map may be automatically co- registered with the therapeutic ultrasound beams. (Mast ii 12). 8. Figure IA of Mast is reproduced below: Time Fig. 1A "FIG. lA generally illustrates a first ultrasound signal 11 returning to an ultrasound transducer (not shown) before treatment of a region of tissue, while ultrasound signal 13 represents an ultrasound signal returning to the ultrasound transducer after treatment of the tissue" (Mast ii 29). 9. Mast teaches that the "relative delay between ultrasound echos returning to an ultrasound transducer, measured before and after treatment, is estimated as a function of depth, ... The slope of the depth-dependent 10 Appeal2014-007832 Application 13/393,857 delay represents echo strain ... The amount of echo strain is proportional to the temperature rise of the heated region" (Mast i-f 29). 10. Sliwa teaches that "catheter body 12 will define at least one lumen 22 ... lumen 22 may be employed, for example, to deliver an irrigating fluid to tip region 20 ... Irrigation may advantageously maintain the acoustic transducer(s) carried by tip region 20 at an acceptable temperature in order to avoid thermal damage thereto" (Sliwa i-f 35). 11. Sliwa teaches that "the tip region of catheter 10 generally includes at least one ablation element, such as a radiofrequency ('RF') electrode, and at least one acoustic transducer" (Sliwa i-f 39) and further teaches "the desirability of making RF electrode 702 both electrically conductive and acoustically transparent, for example by employing a thin film metal overlaid on an acoustically transparent polymer" (Sliwa i-f 56). 12. Barnes teaches that the "acoustic window 20 is glass, plastic, polymer, rubber, or other acoustically transparent material" (Barnes i-f 21 ). 13. The Specification teaches that "the transmission element should be substantially transparent to acoustic radiation. A number of materials, including various polymer materials, fulfill this. In general any material can be used, as long as the transparency is sufficient to enable clinical use as well as to enable detection of the acoustic path length through the element" (Spec. 3:15-18). Principles of Law "The combination of familiar elements according to known methods is likely to be obvious when it does no more than yield predictable results." KSR Int 'l Co. v. Teleflex Inc., 550 U.S. 398, 416 (2007). "If a person of ordinary skill can implement a predictable variation, § 103 likely bars its 11 Appeal2014-007832 Application 13/393,857 patentability." Id. at 417. As noted by the Court in KSR, "[a] person of ordinary skill is also a person of ordinary creativity, not an automaton." Id. at 421. Analysis Claims 1, 2, 4, 5, and 10-13 over Lang and Mast Lang teaches an ultrasound device with an elongated body, proximal and distal ends (FF 4) that includes ultrasound transducers (FF 3), a transmission element that is the acoustic coupling gel 3 (FF 4), and a controller unit that measures the reflected signal (FF 5). Lang does not teach determining acoustic path length or temperature from that acoustic path length. Mast teaches measuring temperature changes based on ultrasound, specifically teaching that "travel time of an ultrasonic echo depends on both the path length" and that "temperature changes in tissue being treated cause measurable alterations to echo travel times" (FF 7). We conclude that the person of ordinary skill reasonably would have found it obvious to modify the ultrasound device of Lang to measure temperature based on travel time of ultrasonic signals as taught by Mast because Mast teaches that "[t]his arrangement is highly desirable, since heating effects of ultrasound treatment may be measured using inexpensive, portable, and unobtrusive ultrasound apparatus" (FF 7). Such a combination is merely a "predictable use of prior art elements according to their established functions." KSR, 550 U.S. at 417. With regard to claim 2, Mast teaches separation of reflection peaks in Figure IA (FF 8), and teaches that this "relative delay between ultrasound 12 Appeal2014-007832 Application 13/393,857 echos returning to an ultrasound transducer ... is proportional to the temperature rise of the heated region" (FF 9). With regard to claim 4, Mast teaches generating acoustic radiation and detecting the acoustic path (FF 7). With regard to claim 5, Mast teaches a functional relationship where the "slope of the depth-dependent delay represents echo strain ... The amount of echo strain is proportional to the temperature rise of the heated region" (FF 9), demonstrating an association between path length and temperature. With regard to claim 10, Lang teaches the ultrasonic device (FF 3-5) while Mast teaches generating and detecting acoustic radiation and using the reflected radiation to analyze the path length and determine a temperature, and the combination of these teachings as discussed above renders the method obvious (FF 7-9). With regard to claim 11, Lang teaches data storage means (FF 6). With regard to claims 12 and 13, we interpret these claims as encompassing ultrasound devices with path lengths that vary based on temperature and Mast teaches ultrasound devices with path lengths that vary based on temperature (FF 7). We will address Appellants' arguments regarding the combination of Lang and Mast. Appellants contend that "Mast teaches a determination of a temperature rise of tissue undergoing ultrasound treatment derived from a pre-ultrasound signal obtained before the treatment and a post-ultrasound signal obtained sometime after commencement of the treatment. See, Mast at paragraphs at [0029]-[0057]" (App. Br. 21-22). 13 Appeal2014-007832 Application 13/393,857 To the extent that Appellants are arguing that Mast does not teach determination of a temperature other than "undergoing ultrasound treatment derived from a pre-ultrasound signal obtained before the treatment and a post-ultrasound signal obtained sometime after commencement of the treatment," we are not persuaded. The claims do not exclude determining of a temperature rise of tissue undergoing ultrasound treatment that is derived from a pre-ultrasound signal obtained before the treatment and a post- ultrasound signal obtained sometime after commencement of the treatment. "[L ]imitations are not to be read into the claims from the specification." In re Van Geuns, 988 F.2d 1181, 1184 (Fed. Cir. 1993). See also In re Self, 671F.2d1344, 1348 (CCPA 1982) ("[A]ppellant's arguments fail from the outset because ... they are not based on limitations appearing in the claims."). Appellants contend that "Mast fails to teach or suggest a modification of Lang directed to the acoustic path through a transmission element of probe 2 of Lang as opposed to an entire acoustic path from the ultras-sonic source within probe 2 (e.g., an ultrasound transducer) to an object 3" (App. Br. 22). We are not persuaded. Appellants' contention fails to account for Lang's contribution to the combination of Lang and Mast (FF 3-5). "Non-obviousness cannot be established by attacking references individually where the rejection is based upon the teachings of a combination of references []. [The reference] must be read, not in isolation, but for what it fairly teaches in combination with the prior art as a whole." In re Merck & Co., 800 F.2d 1091, 1097 (Fed. Cir. 1986). 14 Appeal2014-007832 Application 13/393,857 In regard to claims 5 and 13, we observe that Appellants merely recite the claim limitations. "A statement which merely points out what a claim recites will not be considered an argument for separate patentability of the claim." 3 7 C.F .R. § 41.3 7 ( c )(l)(iv ). Claims 3 and 7-9 over Lang, Mast, and Sliwa Lang and Mast render claim 1 obvious for the reasons given above, but do not teach fluid delivery or polymer-based bodies. With regard to claim 3, Sliwa teaches that "lumen 22 may be employed, for example, to deliver an irrigating fluid to tip region 20" (FF 10). With regard to claims 7-9, Sliwa teaches an acoustically transparent polymer body for an electrode for ablation treatment with an integrated electrode (FF 11 ). We conclude that the person of ordinary skill reasonably would have found it obvious to modify the ultrasound device rendered obvious by Lang and Mast with the ablation electrodes and lumen of Sliwa in order to permit treatment while performing ultrasound, measure temperature and maintain proper ablation electrode temperature (FF 10-11). KSR, 550 U.S. at 417. Claim 6 over Lang, Mast, and Barnes Lang and Mast render claim 1 obvious for the reasons given above, but do not teach the polymer-based body with a particular change of velocity as required by claim 6. The Specification teaches that "[i]n general any material can be used, as long as the transparency is sufficient to enable clinical use" (FF 13), while 15 Appeal2014-007832 Application 13/393,857 Barnes teaches that the "acoustic window 20 is glass, plastic, polymer, rubber, or other acoustically transparent material" (FF 12). The Specification provides no specific structure required by a polymer-based body to have "a change of velocity of the acoustic radiation larger than 0.1 % per degree Celsius", nor does the Specification identify any specific material that is required to achieve this result. We, therefore, agree with the Examiner that the acoustic materials of Barnes, including the polymers, reasonably render claim 6 obvious because these polymers would have been expected to have sufficient transparency for clinical use and would necessarily satisfy the velocity based limitation. See In re Best, 562 F.2d 1252, 1255 (CCPA 1977) ("Where, as here, the claimed and prior art products are identical or substantially identical ... the PTO can require an applicant to prove that the prior art products do not necessarily or inherently possess the characteristics of his claimed product."). SUMMARY We affirm the provisional rejection of claims 1-11 under the judicially created doctrine of obviousness-type double patenting as being unpatentable over claims 1-15 of Barley. We affirm the rejection of claims 12 and 13 under 35 U.S.C. § 112, first paragraph, as failing to comply with the written description requirement. We reverse the rejections under 35 U.S.C. § 102(b) and 35 U.S.C. § 103(a). We reject claims 1, 2, 4, 5, and 10-13 under 35 U.S.C. § 103(a) as being obvious over Lang and Mast. 16 Appeal2014-007832 Application 13/393,857 We reject claims 3 and 7-9 under 35 U.S.C. § 103(a) as obvious over Lang, Mast, and Sliwa. We reject claim 6 under 35 U.S.C. § 103(a) as obvious over Lang, Mast, and Barnes. Regarding the affirmed rejections, 37 C.F.R. § 41.52(a)(l) provides "Appellant may file a single request for rehearing within two months from the date of the original decision of the Board." In addition to affirming the Examiner's rejection(s) of one or more claims, this decision contains new grounds of rejection pursuant to 37 C.F.R. § 41.50(b). 37 C.F.R. § 41.50(b) provides "[a] new ground of rejection pursuant to this paragraph shall not be considered final for judicial review." 37 C.F.R. § 41.50(b) also provides that Appellants, WITHIN TWO MONTHS FROM THE DATE OF THE DECISION, must exercise one of the following two options with respect to the new grounds of rejection to avoid termination of the appeal as to the rejected claims: ( 1) Reopen prosecution. Submit an appropriate amendment of the claims so rejected or new evidence relating to the claims so rejected, or both, and have the matter reconsidered by the Examiner, in which event the proceeding will be remanded to the Examiner. . . . (2) Request rehearing. Request that the proceeding be reheard under § 41.52 by the Board upon the same record .... Should Appellants elect to prosecute further before the Examiner pursuant to 3 7 C.F .R. § 41. 50(b )( 1 ), in order to preserve the right to seek review under 35 U.S.C. §§ 141 or 145 with respect to the affirmed rejection, the effective date of the affirmance is deferred until conclusion of the 17 Appeal2014-007832 Application 13/393,857 prosecution before the Examiner unless, as a mere incident to the limited prosecution, the affirmed rejection is overcome. If Appellants elects prosecution before the Examiner and this does not result in allowance of the application, abandonment or a second appeal, this case should be returned to the Patent Trial and Appeal Board for final action on the affirmed rejections, including any timely request for rehearing thereof. AFFIRMED;§ 41.50(b) 18 Copy with citationCopy as parenthetical citation