Ex Parte LIDownload PDFPatent Trial and Appeal BoardAug 17, 201611893597 (P.T.A.B. Aug. 17, 2016) Copy Citation UNITED STA TES p A TENT AND TRADEMARK OFFICE APPLICATION NO. FILING DATE FIRST NAMED INVENTOR 111893,597 08/16/2007 Yi-QunLi 22798 7590 08/17/2016 QUINE INTELLECTUAL PROPERTY LAW GROUP, P,C POBOX458 ALAMEDA, CA 94501 UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O. Box 1450 Alexandria, Virginia 22313-1450 www .uspto.gov ATTORNEY DOCKET NO. CONFIRMATION NO. 318-02231 ous 5168 EXAMINER FLINDERS, JEREMY C ART UNIT PAPER NUMBER 1639 MAILDATE DELIVERY MODE 08/17/2016 PAPER Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte YI-QUN LI 1 Appeal2014-009981 Application 11/893,597 Technology Center 1600 Before DONALD E. ADAMS, JOHN E. SCHNEIDER, and RYAN H. FLAX, Administrative Patent Judges. SCHNEIDER, Administrative Patent Judge. DECISION ON APPEAL This is an appeal under 35 U.S.C. § 134(a) involving claims to a method for preparing a combinatorial library which have been rejected as obvious. We have jurisdiction under 35 U.S.C. § 6(b). We affirm. STATEMENT OF THE CASE The present invention is directed to compositional gradients of combinatorial materials libraries, where the libraries comprise a compositional gradient of at least two polymer-stabilized liquids deposited on a substrate. The 1 Appellants identify the Real Party in Interest as Intematix Corporation. Appeal Br. 1. Appeal2014-009981 Application 11/893,597 gradient may be of a continuous nature, a linear nature, or a non-linear nature. The compositional gradient combinatorial materials library may comprise a gradient of the first polymer- stabilized liquid ranging from about 100 percent at a first location of the library, and continuously decreases to about zero percent at a second location of the library, and a gradient of the second polymer-stabilized liquid ranging from about 100 percent at the second location of the library, and continuously decreases to about zero percent at the first location of the library. Spec. 3, 11. 3-12. Claims 1-6 and 17-21 are on appeal. 2 Claim 1 is illustrative and reads as follows: 1. A compositional gradient combinatorial materials library compnsmg a compositional gradient formed by at least two polymer- stabilized liquids dispensed to a substrate, the compositional gradient being continuous along the substrate; \vherein the at least t\vo polymer-stabilized liquids each include a solvent and one or more inorganic materials substantially homogenously distributed within the solvent; and wherein subsequent to being dispensed the solvent is evaporated. The claims stand rejected as follows: Claims 1---6 and 17-21 stand rejected under 35 U.S.C. § 103(a) as unpatentable over Moini. 3 2 "Claims 7-16 have been withdraw as being drawn to nonelected subject matter." Final Act. 2 (emphasis removed). 3 Moini et al., US 2003/0190408 Al (published Oct. 9, 2003) ("Moini"). 2 Appeal2014-009981 Application 11/893,597 DISCUSSION Issue In rejecting claims 1---6 and 17-21 the Examiner finds that Moini teaches a compositional gradient library wherein "one or more compositions are in the form of [a] continuous concentration gradient( s) along a substrate." Final Act. 3 (underline original). The Examiner also finds that Moini discloses that the gradient is formed by at least two polymer- stabilized liquids dispensed to a substrate. Id. The Examiner goes on to find that the polymer-stabilized liquids include a solvent, which can be an organic solvent or water and the liquid can contain inorganic materials such as metal salts or oxides. Final Act. 3--4. The Examiner finds that Moini teaches that the solvents are evaporated after they are deposited on the substrate. Final Act. 4. The Examiner concludes that it would have been prima facie obvious for one of ordinary skill in the art at the time of the invention \~1as made to prepare the compositional gradient libraries as per Moini et al. as above and instantly claimed, since Moini et al. teaches that there are a finite number of identified, predictable potential solutions to yield useful compositional gradient libraries, and given that [] one of ordinary skill in the art could have pursued these known potential solutions with a reasonable expectation of success, that selecting and combining of the specific features listed above would have been at least obvious to try. The above cited prior art suggests or motivates the practice of the instant claims and therefore supports a reasonable expectation of success of practicing the limitations of the claimed subject matter. Final Act. 6-7. Appellant contends that Moini teaches two separate embodiments, one involving a continuously changing gradient and other involving separate 3 Appeal2014-009981 Application 11/893,597 discretely displaced arrays and that the Examiner improperly ties aspects of the one embodiment to the other embodiment. Appeal Br. 3. Appellant argues that different techniques are used to make the structures of the two embodiments. Appeal Br. 4. Appellant also argues that the examples are limited to the discrete gradient embodiment and that the teachings are inapplicable to the continuous gradient embodiment. Appeal Br. 5-7. Appellant argues that there is nothing in the reference to suggest applying the teachings related to the discrete gradient embodiment to the continuous gradient embodiment. Appeal Br. 8. The issue with respect to this rejection is whether the Examiner has established by a preponderance of the evidence that claims 1-6 and 17-21 would have been obvious over Moini under 35 U.S.C. § 103(a). Findings of Fact We adopt as our own the Examiner's findings and analysis. The following findings are included for emphasis and reference convenience. FF 1. Moini teaches the formation of "composite samples using one or more coatings in the form of continuous concentration gradients placed on the surface of a substrate." Moini if 22. FF2. The gradient coatings can be generated by using spray coating techniques or screen printing techniques. Moini if 22. FF3. Moini discloses the use of a carrier which contains a solvent and a polymer. Moini iii! 79-86. FF4. Moini teaches that the solvents used in the carrier can be organic solvents and/or water. Moini iii! 79-86. 4 Appeal2014-009981 Application 11/893,597 FF5. Moini teaches that the compositions used to form gradients can contain inorganic materials such as metals and metal oxides. Moini i-fi-136- 40. FF6. Moini teaches that after the composition is deposited, the solvent is removed by heating the coated substrate. Moini i1 73. Principles of Law "The combination of familiar elements according to known methods is likely to be obvious when it does no more than yield predictable results." KSR Int 'l Co. v. Teleflex Inc., 550 U.S. 398, 416 (2007). Analysis Claim 1 is representative of the rejected claims and relates to a compositional gradient combinatorial materials library. We agree with the Examiner that the subject matter of claim 1 would have been obvious to one skilled in the art at the time the invention was made. Moini teaches the formation of "composite samples using one or more coatings in the form of continuous concentration gradients placed on the surface of a substrate." FF 1. Moini applies the coating to a substrate using a carrier which comprises a solvent and a polymer. FF3. The coating can also contain inorganic materials such as metal oxides. FF5. Moini also teaches that after the coating is applied to the substrate, the solvent is removed by heating the coated substrate. FF6. Therefore, we agree with the Examiner's conclusion of obviousness. See Final Act 6-7. Appellant argues that there is no motivation to use the teachings of Moini with respect to discrete gradients in the creation of continuous 5 Appeal2014-009981 Application 11/893,597 gradients. Appeal Br. 3--4. Specifically, Appellant argues that Moini teaches the use of polymers only in the context of discrete gradients formed using screen printing as opposed to spray printing used to make continuous gradients. Id. Appellant argues that one skilled in the art would not use a viscous fluid in spray applications, hence they would not use the fluids for discrete gradients to make a continuous gradient. Id. We are unpersuaded. As the Examiner has found, Moini teaches only one type of coating and states that the coatings can be used to form continuous gradients. Ans. 9. Moini teaches that continuous gradients can be formed by any number of techniques including "screen printing techniques." Moini i-f 22. We agree with the Examiner that one skilled in the art would have been motivated to use the coating composition disclosed in Moini for both discrete and continuous gradients. Ans. 11. Appellant argues that the only examples in Moini relate to discrete gradients and that the Examiner's position that Figure 8 discloses a continuous gradient is in error. Appeal Br. 6. We remain unpersuaded. As discussed above, Moini clearly teaches all of the elements of claim 1. FF 1- 6. That the examples may be limited to a different embodiment is irrelevant. Conclusion of Law We conclude that the Examiner has established by a preponderance of the evidence that claim 1 would have been obvious over Moini as defined by 35 U.S.C. § 103(a). Claims 2-6 and 17-21 have not been argued separately and therefore fall with claim 1. 6 Appeal2014-009981 Application 11/893,597 SUMMARY We affirm the rejection of claims 1---6 and 17-21. TIME PERIOD FOR RESPONSE No time period for taking any subsequent action in connection with this appeal may be extended under 37 C.F.R. § 1.136(a). AFFIRMED 7 Copy with citationCopy as parenthetical citation