Ex Parte Lakshminarayan et alDownload PDFPatent Trial and Appeal BoardSep 22, 201613157009 (P.T.A.B. Sep. 22, 2016) Copy Citation UNITED STA TES p A TENT AND TRADEMARK OFFICE APPLICATION NO. FILING DATE FIRST NAMED INVENTOR 13/157,009 06/09/2011 Choudur Lakshminarayan 56436 7590 09/26/2016 Hewlett Packard Enterprise 3404 E. Harmony Road Mail Stop 79 Fort Collins, CO 80528 UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O. Box 1450 Alexandria, Virginia 22313-1450 www .uspto.gov ATTORNEY DOCKET NO. CONFIRMATION NO. 82690114 6235 EXAMINER SUGENT, JAMES F ART UNIT PAPER NUMBER 2175 NOTIFICATION DATE DELIVERY MODE 09/26/2016 ELECTRONIC Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. Notice of the Office communication was sent electronically on above-indicated "Notification Date" to the following e-mail address( es): hpe.ip.mail@hpe.com mkraft@hpe.com chris.mania@hpe.com PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte CHOUDUR LAKSHMINARA YAN, ALEXANDER SINGH ALVARADO, and JOSE C. PRINCIPE Appeal2014-009124 Application 13/157,009 Technology Center 2100 Before ERIC S. FRAHM, LARRY J. HUME, and JOHN D. HAMANN, Administrative Patent Judges. FRAHM, Administrative Patent Judge. DECISION ON APPEAL STATEMENT OF CASE Introduction Appellants appeal under 35 U.S.C. § 134(a) from a final rejection of claims 1-20. We have jurisdiction under 35 U.S.C. § 6(b ). We affirm. Disclosed and Claimed Invention Appellants' disclosed invention relates to adaptive sampling of integrate and fire (IF) time encoded neural (i.e., brain) signals (Fig. 1; Spec. i-fi-11-3 and 12-14; Abs.) in order to separate neurons into different classes (Spec. i-fi-1 17, 25, 26, 31; Fig. 2 shows class assignment module 220 Appeal2014-009124 Application 13/157,009 operating as described in if 31; Fig. 5 shows classes N 1 and N2 of neurons plotted in Figs. 4a and 4b as described in iii! 33-36). Exemplary Claim Exemplary independent claim 1 under appeal, with emphasis added to the contested limitation, reads as follows: 1. A method of time encoding using an integrate and fire (IF) sampler, comprising: receiving input signals for separate classes; generating a pulse train based on the input signals; and binning the pulse train to generate a feature vector for each of the separate classes. Examiner's Rejections ( 1) The Examiner rejected claims 1--4, 7, 11-14, 1 7, and 18 as being unpatentable under 35 U.S.C. § 103(a) over the combination of Alvarado, Alexander Singh et al., Stimulus reconstruction from the biphasic integrate- and-fire sampler, PROCEEDINGS OF THE 4rn INTERNATIONAL IEEE EMBS CONFERENCE ON NEURAL ENGINEERING ANTAL YA, TURKEY, pp. 415-18 (April 29 - May 2, 2009) (hereinafter, "Alvarado") and Nedungadi, Aatira et al., Analyzing multiple spike trains with nonparametric granger causality, J COMPUT NEUROSCI, Vol. 27, pp. 55---64 (Jan. 10, 2009) (hereinafter, "Nedungadi"). Final Act. 3-5; Ans. 3---6. (2) The Examiner rejected claims 5, 6, 15, and 19 as being unpatentable under 35 U.S.C. § 103(a) over the combination of Alvarado, Nedungadi, and Sanchez, Justin C., et al., Technology and Signal Processing 2 Appeal2014-009124 Application 13/157,009 for Brain-Machine interfaces, IEEE SIGNAL PROCESSING MAGAZINE, pp. 29- 40 (2008) (hereinafter, "Sanchez"). Final Act. 5---6; Ans. 6-7. (3) The Examiner rejected claims 8, 9, 16, and 20 as being unpatentable under 35 U.S.C. § 103(a) over the combination of Alvarado, Nedungadi, and Lansky, Petr et al., Classification of stimuli based on stimulus-response curves and their variability, BRAIN RESEARCH, Vol. 1225, pp. 57---66 (April 30, 2008) (hereinafter, "Lansky''). Final Act. 6-8; Ans. 7-9. (4) The Examiner rejected claim 10 as being unpatentable under 35 U.S.C. § 103(a) over the combination of Alvarado, Nedungadi, and Foffani, Guglielmo et al., PSTH-based classification of sensory stimuli using ensembles of single neurons, JOURNAL OF NEUROSCIENCE METHODS, Vol. 135, pp. 107-20 (2004) (hereinafter, "Foffani"). Final Act. 8-9; Ans. 9-10. Appellants' Contentions (1) Appellants contend (App. Br. 6; Reply Br. 5) the Examiner erred in rejecting claims 1--4, 7, 11-14, 17, and 18 under 35 U.S.C. § 103(a) over the combination of Alvarado and Nedungadi based on an interpretation that claim 1 requires binning separate classes of neurons and not each neuron individually. Therefore, Appellants assert that Nedungadi fails to disclose, and as a result the base combination of Alvarado and Nedungadi fails to teach or suggest, a method for time encoding using an IF sampler, including "binning the pulse train to generate a feature vector for each of the separate classes," as recited in claim 1. Specifically, Appellants contend (Reply Br. 5) that Nedungadi discloses binning each neuron, and not separate classes of neurons as recited in claim 1, and the portions of Appellants' Specification cited by the Examiner in the response to Appellants' 3 Appeal2014-009124 Application 13/157,009 arguments in the Appeal Brief (see Ans. 12-13 citing Nedungadi iii! 13, 25, 29, and 36; Figs. 4a, 4b, and 5) make it clear that classes are subsets and not every neuron, thus classes cannot be neurons. (2) Appellants' remaining arguments as to the rejections of dependent claims 5, 6, 10, 15, and 19 are based on the same interpretation of "classes" as argued for claim 1. (3) Appellants also contend (App. Br. 9-11) that Lansky fails to (a) act based on a feature vector as recited in claim 8; (b) discuss a likelihood ratio as recited in claim 9; and ( c) assign classes based on conditional probability densities as recited in claims 16 and 20. Issues on Appeal Based on Appellants' arguments in the Appeal Brief (App. Br. 5-12) and the Reply Brief (Reply Br. 3-7), the following two issues are presented on appeal: (1) Did the Examiner err in rejecting claims 1-7, 10-15, and 17-19 as being obvious over the base combination of Alvarado and Nedungadi because (a) a proper interpretation of representative claim 1 requires binning separate classes of neurons and not each neuron individually; and (b) thus Nedungadi fails to disclose, and as a result the base combination of Alvarado and N edungadi fails to teach or suggest, a method for time encoding using an IF sampler, including "binning the pulse train to generate a feature vector for each of the separate classes," as recited in representative claim 1? (2) Did the Examiner err in rejecting claims 8, 9, 16, and 20 as being obvious because Lansky fails to teach or suggest the limitations at issue of (i) acting based on a feature vector (claim 8); (ii) using a likelihood ratio (claims 9 and 20); and/or (iii) assigning classes based on conditional 4 Appeal2014-009124 Application 13/157,009 probability densities (claim 16), as set forth in the respective dependent claims? ANALYSIS We have reviewed the Examiner's rejections (Final Act. 3-9; Ans. 3-10) in light of Appellants' contentions in the Appeal Brief (App. Br. 5-12) and the Reply Brief (Reply Br. 3-7) that the Examiner has erred, as well as the Examiner's response to Appellants' arguments in the Examiner's Answer found at pages 11-17. We disagree with Appellants' conclusions. Claims 1-7, 10--15, and 17-19 With regard to representative independent claim 1, we adopt as our own ( 1) the findings and reasons set forth by the Examiner in the action from which this appeal is taken (Final Act. 3--4; Ans. 4) with the exception that we agree with the Examiner (Ans. 4) the final vector D ofNedungadi is equivalent to the recited feature vector in claim 1 (and not the vector counting variable N(t) relied on by the Examiner at Final Act. 3), and (2) the reasons set forth by the Examiner in the Examiner's Answer in response to Appellants' Appeal Brief (see Ans. 11-13). Based on our interpretation of the term "classes" recited in representative claim 1, we concur with the conclusions reached by the Examiner with regard to the obviousness of representative claim 1 in view of the base combination of Alvarado and Nedungadi. "During examination, 'claims ... are to be given their broadest reasonable interpretation consistent with the specification, and ... claim language should be read in light of the specification as it would be interpreted by one of ordinary skill in the art."' In re Am. Acad. of Sci. Tech 5 Appeal2014-009124 Application I3/157,009 Ctr., 367 F.3d I359, I364 (Fed. Cir. 2004) (quoting Jn re Bond, 9IO F.2d 83I, 833 (Fed. Cir. I990)); see also In re Morris, I27 F.3d I048, I053-54 (Fed. Cir. I997). In this light, we agree with the Examiner (Ans. I2-I3) that the claims on appeal do not actually require or contain limitations requiring a class to be a subset or a plurality of neurons, as opposed to individual neurons. Claim I on appeal simply recites a method of encoding by "receiving input signals for separate classes," using the input signals to generate a pulse train, and "binning the pulse train to generate a feature vector for each of the separate classes" (claim I) (emphases added). Claim I does not specify what the classes are, or what the classes consist of, other than to state that a feature vector is generated "for each of the separate classes" (claim I). Turning to Appellants' Specification, we find Figures 4a and 4b show two separate classes (Class I in Fig. 4a and Class 2 in Fig. 4b ), and Figure 5 shows a distribution of projections of two classes NI and N2 taken from Figures 4a and 4b (see Spec. i-fi-13 I-36). The Specification is relatively silent as to the composition of the classes (see Spec. i-fi-f I 7, 25, 26, 29, 3 I, 45 all describing the classes as being separate; Fig. 2 showing class assignment module 220 operating as described in i-f3 I). However, paragraph I 3 of Appellants' Specification does describe that the IF sampler uses time-based encoding with "linear discriminant analysis" to discriminate features of the input signal (such as "action potentials from two separate neurons"). It follows that Appellants disclose two separate classes of neurons (e.g., Classes I and 2 shown in Figs. 4a and 4b and neurons NI and N2 shown in Fig. 5) are discriminated for subsequent use in generating a feature vector from a pulse train generated using the input signals, each having a different 6 Appeal2014-009124 Application 13/157,009 action potential from the other. Therefore, the Examiner's interpretation that classes are neurons as supported by paragraphs 13, 25, 29, and 36 and Figures 4a, 4b, and 5 is reasonable. Final vector Din Nedungadi is a "binned data vector" (Nedungadi, p. 57, Section 2.1) generated from a group of m neurons including ith andjth neurons (Nedungadi, p. 56, Section 2.1). In view of the Specification's descriptions (or lack thereof) of the separate classes discussed supra, we agree with the Examiner (Ans. 12-13) that Nedungadi's ith andjth neurons meet the claim language of "separate classes" set forth in claim 1. As a result of this interpretation, which is supported by Appellants' Specification and Drawings, we find Nedungadi discloses binning a pulse train to generate a final vector for separate classes as recited in claim 1. We also agree with the Examiner's findings regarding Alvarado (see Final Act. 3; Ans. 4), and note the striking similarity of Appellants' Figure 1 and Alvarado's Figure 1. The base combination of Alvarado and Nedungadi therefore teaches, or at least suggests, the method for time encoding using an IF sampler, including "binning the pulse train to generate a feature vector for each of the separate classes," as recited in representative claim 1. In view of the foregoing, we sustain the Examiner's rejection of representative independent claim 1 over the base combination of Alvarado and Nedungadi, as well as claims 2--4, 7, 11-14, 17, and 18 grouped therewith. For similar reasons, and because Appellants ultimately rely on the same arguments as to claim 1 for the patentability of dependent claims 5, 6, 10, 15, and 19 (see App. Br. 8-9 and 12), we also sustain the Examiner's rejections of (i) claims 5, 6, 15, and 19 over the combination of Alvarado, 7 Appeal2014-009124 Application 13/157,009 Nedungadi, and Sanchez; and (ii) claim 10 over the combination of Alvarado, Nedungadi, and Foffani. Claims 8, 9, 16, and 20 Appellants' contentions (App. Br. 9-11) that the Examiner erred in determining the combination of Alvarado, Nedungadi, and Lansky teaches or suggests the methods or systems for time encoding using an IF sampler recited in claims 8, 9, 16, and 20 are unpersuasive. With regard to claim 8, we agree with the Examiner (Final Act. 6-7; Ans. 16) that (i) the base combination of Alvarado and Nedungadi, and not Lansky, is relied upon as teaching or suggesting acting based on a feature vector; and (ii) Lansky (pages 57-58; Fig. 2, showing probability functions) teaches or suggests using a conditional probability density to assign classes. With regard to claim 9, we agree with the Examiner (Final Act. 7; Ans. 8 and 16) that Lansky teaches or suggests the equivalent of the recited likelihood ratio at page 59, section 2.2 by determining response distributions and probability density functions as shown in Figure 2. Appellants' contention (App. Br. 10) that Lansky fails to discuss a likelihood ratio is not persuasive and no evidence has been presented, only attorney argument, to show that Lansky's response distributions and probability density functions are not the equivalent of the recited likelihood ratio of a conditional probability density. With regard to claims 8, 16, and 20, we agree with the Examiner (Final Act. 6-8; Ans. 7-9 and 16-17) that the base combination of Alvarado and Nedungadi, and not Lansky, is relied upon as teaching or suggesting assigning classes based on conditional probability densities. In view of the 8 Appeal2014-009124 Application 13/157,009 foregoing, we sustain the Examiner's rejection of claims 8, 9, 16, and 20 over the combination of Alvarado, Nedungadi, and Lansky. CONCLUSIONS ( 1) The Examiner has not erred in rejecting claims 1-7, 10-15, and 17-19 as being obvious over the base combination of Alvarado and Nedungadi because (a) representative claim 1 does not require separate classes of neurons as Appellants argue (Reply Br. 4), but instead merely receives "input signals for separate classes" without specifying what the classes are for or consist of other than to state that a feature vector is generated "for each of the separate classes" (claim 1 ); and (b) N edungadi discloses, and the base combination of Alvarado and Nedungadi teaches or suggests, the method for time encoding using an IF sampler, including "binning the pulse train to generate a feature vector for each of the separate classes," as recited in representative claim 1. (2) Appellants have not shown the Examiner erred in rejecting claims 8, 9, 16, and 20 as being unpatentable under 35 U.S.C. § 103(a). Accordingly, we affirm the obviousness rejections of claims 8, 9, 16, and 20 over Alvarado, Nedungadi, and Lansky. DECISION We affirm the Examiner's rejections of claims 1-20. No time period for taking any subsequent action in connection with this appeal may be extended under 37 C.F.R. § 1.136(a)(l )(iv). AFFIRMED 9 Copy with citationCopy as parenthetical citation