Cupron Inc. et al.Download PDFPatent Trials and Appeals BoardApr 1, 20212020001919 (P.T.A.B. Apr. 1, 2021) Copy Citation UNITED STATES PATENT AND TRADEMARK OFFICE UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O. Box 1450 Alexandria, Virginia 22313-1450 www.uspto.gov APPLICATION NO. FILING DATE FIRST NAMED INVENTOR ATTORNEY DOCKET NO. CONFIRMATION NO. 14/420,518 02/09/2015 Kenneth Gauthier Trinder II CUP013.US 4331 129507 7590 04/01/2021 Pike IP Law, PLLC P.O. Box 8592 Richmond, VA 23226 EXAMINER CABRAL, ROBERT S ART UNIT PAPER NUMBER 1618 NOTIFICATION DATE DELIVERY MODE 04/01/2021 ELECTRONIC Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. Notice of the Office communication was sent electronically on above-indicated "Notification Date" to the following e-mail address(es): bernard.pike@pikeiplaw.com docket@pikeiplaw.com PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte KENNETH GAUTHIER TRINDER II and VIKRAM KANMUKHLA Appeal 2020-001919 Application 14/420,518 Technology Center 1600 Before DONALD E. ADAMS, JOHN G. NEW, and TAWEN CHANG, Administrative Patent Judges. CHANG, Administrative Patent Judge. DECISION ON APPEAL Pursuant to 35 U.S.C. § 134(a), Appellant1 appeals from the Examiner’s decision to reject claims 1, 2, 4–9, 50, and 56–62.2 We have jurisdiction under 35 U.S.C. § 6(b). We AFFIRM. 1 We use the word “Appellant” to refer to “applicant” as defined in 37 C.F.R. § 1.42. Appellant identifies the real party in interest as Cupron, Inc. Appeal Br. 2. 2 Appellant states that “[c]laims 1, 2, 4–9, 15–18, 21–24, 26–28, 32–36, 39– 42, 44–46, 50, and 56–62 are pending” and that “all the pending claims are Appeal 2020-001919 Application 14/420,518 2 STATEMENT OF THE CASE The Specification states that “bacteria, fungi, and viruses . . . have the possibility of establishing a presence on the hard surface. Such surfaces provide an entrée into the host by the pathogenic microorganisms, which can negatively impact morbidity and mortality.” Spec. ¶ 2. The Specification further states that “[o]ne means for eradicating or diminishing contact exposure to microbes present on solid surfaces is to incorporate an antimicrobial compound within or on the solid surface” and that “[c]opper ion releasing compounds, such as copper oxide[,] are known to be highly effective microcidal agents.” Id. ¶ 3. For example, the Specification notes that “[c]ounter tops made from copper and its alloys are effective in controlling the microbial burden on a hard surface of counter top.” Id. ¶ 5. According to the Specification, however, “copper and its alloys are expensive and the practicality of their incorporation is both technically challenging and expensive. In addition, in many cases a metal hard surface can often be unattractive due to oxidation staining as well as difficult to maintain esthetically.” Spec. ¶ 6. Moreover, further according to the Specification, “[w]hile it was previously known that the incorporation of copper within composite structural solid materials imparts antimicrobial activity to the same, . . . , composite structural solid materials to date were limited in that loading of more than 10% w/w of copper-containing particles within such materials was not attainable.” Spec. ¶ 8. being appealed.” Appeal Br. 2. However, claims 15–18, 21–24, 26–28, 32– 36, 39–42, and 44–46 have been withdrawn. Appeal Br. 17. Accordingly, they are not before us on appeal. Appeal 2020-001919 Application 14/420,518 3 The Specification asserts that the invention at issue on appeal “provides high copper oxide loaded composite structural solid materials which are biocidal.” Spec. ¶ 9. . CLAIMED SUBJECT MATTER The claims are directed to a composite structural solid material. Claims 1 and 50 are illustrative: 1. A composite structural solid material comprising: a polymeric panel or slab polymerized from a polymeric resin in a mold, wherein the polymeric resin comprises thermoset resins; copper oxide particles dispersed within the polymeric panel or slab, wherein the copper oxide particles are added by use of a copper containing masterbatch; and a filler material distributed within the polymeric resin, wherein said copper oxide is present at a concentration ranging from 10 to 50% w/w% and wherein a portion of said copper oxide particles are surface exposed. 50. A composite structural solid material prepared by a continuous pour process for the manufacture of a composite structural solid material comprising a polymeric resin and copper oxide particles substantially uniformly dispersed therein the process comprising the steps of: • mixing a filler with copper oxide containing masterbatch until well blended to form a filler-copper oxide blend; • stepwise, subsequently mixing said filler-copper oxide blend with a thermoset resin and optionally a pigment to form a copper oxide containing blended composition; • stepwise, subsequently mixing a catalyst with said copper oxide containing blended composition to form a polymerizable composite structural material; • distributing said polymerizable composite structural material in a mold; and • providing conditions for polymerization of said polymerizable composite structural material, Appeal 2020-001919 Application 14/420,518 4 thereby preparing a composite structural solid material, wherein the polymeric resin comprises thermoset resins. Appeal Br. 16–17 (Claims App.). REJECTION(S) A. Claims 1, 2, 4–9, 50, and 59–62 are rejected under pre-AIA 35 U.S.C. 103(a) as being unpatentable over Fritz3 and Gabbay.4 Final Act. 5. B. Claims 56 and 58 are rejected under pre-AIA 35 U.S.C. 103(a) as being unpatentable over Fritz, Gabbay, and Trinder.5 Final Act. 8. C. Claim 57 is rejected under pre-AIA 35 U.S.C. 103(a) as being unpatentable over Fritz, Gabbay, Trinder, and Scher.6 Final Act. 9. D. Claim 50 is rejected under 35 U.S.C. 112, second paragraph, as being indefinite. Final Act. 4. OPINION A. Obviousness rejection over Fritz and Gabbay (claims 1, 2, 4–9, 50, and 59–62) 1. Issue The Examiner finds that Fritz teaches almost all of the limitations of independent claim 1, except that Fritz does not teach “copper oxide particles dispersed within [a] polymeric panel or slab, wherein the copper oxide particles are added by use of a copper-containing masterbatch” and “is 3 Fritz et al., US 9,259,083 B1, issued Feb. 16, 2016. 4 Gabbay, US 2013/0195841 A1, published Aug. 1, 2013. 5 Trinder et al., US 2006/0125137 A1, published June 15, 2006. 6 Scher et al., US 5,260,006, issued Nov. 9, 1993. Appeal 2020-001919 Application 14/420,518 5 present at a concentration ranging from 10 to 50 w/w%,” and “wherein a portion of said copper oxide particles are surface exposed.” Final Act. 5. However, the Examiner finds that “Gabb[a]y relates to incorporation of copper oxide in a polymeric resin to provide antimicrobial properties to the material” and “teaches that ‘a master batch formulation is prepared at a concentration of between 20% and 40% copper oxide w/w for inclusion in the slurry state of a polymer for use.’” Id. The Examiner finds that Gabbay also teaches that “[a] typical formulation would comprise . . . in addition to the copper oxide, a dispersant, for example a wax and, if desired, a thermoplastic polymer,” wherein “[t]he thermoplastic polymer assists the dispersing of the wax throughout the slurry,” and “[t]he wax serves to disperse the copper oxide and other additives evenly and finely in the formulation and to stabilize the dispersion.” Id. The Examiner finds that Gabbay further teaches that [t]he copper oxide can be included in a polymer, or attached to a polymer after it is shaped, can be placed as a coating on a hard surface, or included in a polymer that is then attached to a hard surface, or can be applied directly to the materials from which the surface material is constructed such as rubber (artificial and natural), urethane compounds, polymers, ceramics, composite stones or marbles, products used in the formation of table tops, and softer materials such as those used in floorings. Id. at 6. Accordingly, the Examiner finds that Gabbay teaches or suggests the “wherein a portion of . . . copper oxide particle are surface exposed.” Id. The Examiner concludes that “[i]t would have been prima facie obvious to one of ordinary skill in the art at the time of the invention to modify the teachings of Fritz . . . by incorporating copper oxide as taught by Gabbay to introduce antimicrobial properties to the composition of Fritz,” Appeal 2020-001919 Application 14/420,518 6 because “it is generally obvious to add known ingredients to known compositions with the expectation of obtaining their known function.” Final Act. 6. With respect to independent claim 50, the Examiner notes that the claim is a product-by-process claim and that, “[t]hus, the determination of the patentability is based on the product itself and not the process recited in the claims.” Final Act. 7. The Examiner concludes that, “[b]ecause the prepared product is also a composite structural solid material comprising a polymeric resin and copper oxide particles substantially uniformly dispersed as recited in claim 1, Fritz . . . and Gabby’s combined disclosures as discussed with respect to claim 1 [above] would address this claim.” Id. Appellant contends that the claims on appeal “should be allowable because the prior art does not enable production of the composite structural solid material, the chemical arts are unpredictable, not all the claim limitations are taught in the prior art references, and the problem and the solution were not known in the prior art.” Appeal Br. 3–4. Appellant does not separately argue the claims. We therefore focus our analysis on claims 1 and 50 as representative. The issue with respect to this rejection is whether a preponderance of the evidence of record supports the Examiner’s conclusion that claims 1 and 50 are obvious over the combination of Fritz and Gabbay. 2. Findings of Fact 1. Fritz teaches a composite, solid surface article. Fritz Abstract; see also id. at 2:53–55 (“new composite countertops”), 3:1–3 & 3:46–48 (describing Figures 1 and 2 as “schematic cross-section view[s] of . . . example solid-surface-composite article[s]” 100 and 200, respectively). Appeal 2020-001919 Application 14/420,518 7 2. Fritz teaches “a method for forming a countertop,” including “providing a base material that may include resin, a coloring pigment, a catalyst, microspheres and resin filler (i.e., such as calcium carbonate, wood, sand, mica, fiberglass, fly ash, and other suitable materials).” Id. at 1:46–50. 3. Fritz teaches that “[t]he base material is mixed and dispensed into a mold and cured.” Id. at 1:51–52, 1:63–64; see also id. at 8:9–13 (claim 1), 6:43–46 & 7:5–8 (teaching that catalyzed base material may be worked or lightly mixed with additives to form stone patterning and that “[t]he catalyzed stone mixture can be packed into a flexible mold,” which can be removed after curing). 4. More particularly, Fritz teaches that its composite, solid surface articles “may be formed of thermoset and thermoplastic resin, a curing agent, microspheres, resin filer and or desired fillers, and additives.” Id. at 4:62–64. 5. Fritz teaches that “[a] curing agent is selected from materials that can initiate cross-linking of the chosen thermoset resin. Thus, polyester resins will typically use methyl ethyl ketone peroxide and a blend of CHP as needed as a curing agent while bisphenol resins will typically use an amine based curing agent.” Id. at 5:1–6. 6. Fritz teaches that “[t]he amount of curing agent used is dependent on the amount of thermoset resin used in the composition. For thermoset resins such as polyester resins, the amount of curing agent used may be varied to increase or decrease the cure time of the catalyzed base material.” Id. at 5:6–11; see also id. at 5:34–45 (stating that “[t]he amount of curing agent is based on the type of thermoset resin chosen, desired cure time, and the thickness of the object being formed” and that “[t]he amounts Appeal 2020-001919 Application 14/420,518 8 of resin, curing agent and microspheres are chosen so that the resulting homogeneous mixture will have a suitable viscosity to form a catalyzed base material”), 6:29–35 (“The amount of thermoset resin used is determined by the amount of product needed. The amount of curing agent needed is based on the thermoset resin chosen, amount of thermoset resin, thickness of material being formed, and the desired cure time.”). 7. Fritz teaches that “[t]he order of mixing the resin, curing agent and microspheres to form a catalyzed base mixture can be varied depending on application.” Id. at 5:59–61; see also id. at 5:62–6:9 (describing various order of mixing ingredients), 6:28–40 (describing embodiments in which “an artificial material [is] prepare directly at the point of use,” wherein curing agent is added to thermoset resin, the catalyzed resin mixture is mixed, and the “microspheres are added by pouring directly over the top of the catalyzed resin mixture with generally homogeneous mixing to form the catalyzed base material”). 8. Fritz teaches that “microspheres may be homogeneously distributed in the catalyzed base material.” Id. at 6:19–20. 9. Gabbay teaches “a biofilm resistant material comprising an active agent, which consists essentially of an insoluble copper oxide at a concentration of between 3 and 10% w/w of said biofilm resistant material and uses thereof.” Gabbay Abstract, ¶¶ 7, 12. 10. Gabbay teaches “a method of inhibiting, diminishing or abrogating microbial biofilms or microbial biofilm formation or a combination thereof on a material surface,” comprising (1) “producing such material with at least a surface comprising an active agent consisting essentially of an insoluble copper oxide at a concentration of between 3 and Appeal 2020-001919 Application 14/420,518 9 10% w/w of the biofilm resistant material” or (2) “attaching to a portion of a surface of said material an active agent consisting essentially of an insoluble copper oxide such that said insoluble copper oxide is at a concentration of between 3 and 10% w/w of said material.” Id. ¶¶ 81–82, claims 18, 19. 11. Gabbay teaches embodiments in which “the biofilm resistant material[] further comprises a polymeric resin.” Id. ¶ 13; see also id. at claims 2, 3. 12. Gabbay teaches that [i]t is to be understood that the preparation of the polymers may be by any means known in the art. For example, and in some embodiments, a polymer concentrate comprising at least one of an oxide of copper, a polyethylene wax prepared from ethylene and, if desired, one or more olefins using a chelating agent catalyst, if desired a thermoplastic polymer and, if desired, other additives is prepared and added to a carrier polymer in the form of a master batch concentration. In some embodiments, only a partial preparation of the powder is necessary, such as only dispersing the powder in a wax, and in some cases the powder can be added directly to the carrier. [i]n some embodiments, a master batch formulation is prepared at a concentration of between 20% and 40% copper oxide w/w for inclusion in the slurry state of a polymer for use. The master batch may be diluted to between 3% and 10% copper oxide to achieve the desired composition. A typical formulation would comprise, in some embodiments, in addition to the copper oxide, a dispersant, for example a wax, and, if desired, a thermoplastic polymer, usually a polyolefin. The thermoplastic polymer assists the dispersing of the wax throughout the slurry. The wax serves to disperse the copper oxide and other additives evenly and finely in the formulation and to stabilize this dispersion. In some embodiments, an envisioned formulation of such a concentrate for a master-batch would comprises 20-40% by weight of Appeal 2020-001919 Application 14/420,518 10 copper oxide, 10% by weight of wax, 2% chelating agent and the balance by weight of a thermoplastic polymer. The ratios of the individual components can be varied within certain limits. Id. ¶¶ 74–76. 13. Gabbay teaches that a skilled artisan will recognize that using copper oxide as the active ingredient to attack the biofilm has application to a variety of hard surfaces. The copper oxide can be included in a polymer, or attached to a polymer after it is shaped, can be placed as a coating on a hard surface, or included in a polymer that is then attached to a hard surface, or can be applied directly to the materials from which the surface material is constructed such as rubber (artificial and natural), urethane compounds, polymers, ceramics, composite stones or marbles, products used in the formation of table tops, and softer materials such as those used in floorings. Id. ¶ 80. 3. Analysis Unless otherwise noted, we adopt the Examiner’s findings of fact and reasoning regarding the rejection of claims 1 and 50 as obvious over Fritz and Gabbay. (Final Act. 5–6, 7; Ans. 3–6; FF1–FF13). We address Appellant’s arguments below. Only those arguments timely made by Appellant in the Appeal Brief (no Reply Brief was submitted) have been considered; arguments not so presented in the Brief are waived. See 37 C.F.R. § 41.37(c)(1)(iv) (2015); see also Ex parte Borden, 93 USPQ2d 1473, 1477 (BPAI 2010) (informative) (“Any bases for asserting error, whether factual or legal, that are not raised in the principal brief are waived.”). Appellant first contends that Fritz “does not produce a composite structural solid material comprising copper oxide . . . present at a Appeal 2020-001919 Application 14/420,518 11 concentration ranging from 10 to 50% w/w% and wherein a portion of said copper oxide particles are surface exposed.” Appeal Br. 4. To the extent Appellant intends this as a stand-alone argument against the obviousness rejection, we are not persuaded. “Non-obviousness cannot be established by attacking references individually where the rejection is based upon the teachings of a combination of references. . . . [The reference] must be read, not in isolation, but for what it fairly teaches in combination with the prior art as a whole.” In re Merck & Co., 800 F.2d 1091, 1097 (Fed. Cir. 1986). In this case, the Examiner cites Gabbay as disclosing the limitations with respect to copper oxide. Appellant further contends that “the inventor was first to develop polymerize [sic] thermoset polymers in the presence of copper oxides,” that “[t]h[e] problems with this combination were not known in the prior art,” and that “the solution required an invention due to the unpredictable interactions between the components.” Appeal Br. 4. Appellant contends that replacing Fritz’s microspheres with copper oxide would only work if “the filler is first mixed with the copper oxide containing masterbatch until well blended to form a filler-copper oxide blend prior to adding the copper oxide to the resin and the catalyst.” Id. at 5. Appellant contends that Fritz teaches “mixing the microspheres (copper oxide) directly with the resin, . . . with the curing agent, or both to form the premixes” but “does not teach, suggest or motivate one skilled in the art to mix the filler with the copper oxide containing masterbatch.” Id. at 5–6. Appellant does not specify whether its argument is that a skilled artisan would not have had reason to combine the disclosures of Fritz and Gabbay, with a reasonable expectation of success, or that the prior art Appeal 2020-001919 Application 14/420,518 12 combination is not enabling with respect to the claimed invention.7 We do not find Appellant’s argument to be persuasive in either case. To the extent Appellant’s argument is that a skilled artisan would not have had reason to combine the Fritz and Gabbay to arrive at the claimed invention, with a reasonable expectation of success, we disagree because, as the Examiner points out, a skilled artisan would have had reason to incorporate the copper oxide taught in Gabbay into the composite material taught by Fritz, in order to obtain the advantages of biofilm resistance described in Gabbay. Ans. 5. Furthermore, a skilled artisan would have had a reasonable expectation of success at arriving at the invention of claims 1 and 50 via the combination because Fritz and Gabbay together discloses all of the limitations of claim 1, and, as conceded in the Declaration of Ed Locke8 attached as Appendix C to the Appeal Brief, “polymerization technologies and reactions are well known” even if the specific claimed composite structural solid material comprising a polymeric panel has not been previously disclosed. Thus, as the Examiner points out (Final Act. 6), combining Fritz and Gabbay merely involves combining familiar elements using known methods, which is likely to be obvious when it yields only 7 In the Answer, the Examiner asserts that Appellant’s arguments are applicable only to claim 50, a product-by-process claim, because claim 1 and its dependent claims do not require any particular order of mixing ingredients. Ans. 3–4. We disagree and do not adopt this portion of the Examiner’s response to the extent the Examiner does not take into account the potential relevance of the arguments to reasonable expectation of success and to whether the prior art is enabling with respect to the claimed invention. 8 Declaration of Ed Locke (July 4, 2018) (“Locke Declaration”). Appeal 2020-001919 Application 14/420,518 13 predictable results. KSR Int’l Co. v. Teleflex Inc., 550 U.S. 398, 416 (2007). For the reasons discussed further below, Appellant has not provided persuasive evidence of unpredictable results commensurate with the scope of the claims.9 In this regard, we further note that “[o]bviousness does not require absolute predictability of success,” only “a reasonable expectation of success.” In re O’Farrell, 853 F.2d 894, 903-04 (Fed. Cir. 1988). To the extent Appellant’s argument is that the cited combination of prior art does not enable the claimed invention, we first note that the Examiner’s rejection does not appear to be based on, as Appellant asserts, replacing Fritz’s microspheres with copper oxide. Compare Appeal Br. 6 (stating that “[t]he inventors found that copper oxide . . . could not be directly substituted with the microspheres [of Fritz] as suggested by the examiner”) and 8–9 (alleging the Examiner’s reliance on In re Lindner is improper because in this case Fritz’s microspheres would be substituted with copper oxide rather than another filler and stating that “[t]he method . . . in Fritz et al. could not be performed by mere replacement of the microspheres with the copper oxide of Gabbay”) with Ans. 6 (stating that Appellant’s 9 Appellant contends that “one skilled in the art would understand the complexity and unpredictability of addition of an ionic species into a radical or ionic initiated polymerization as produced by [the] combination” of Gabbay and Fritz and that “[t]he results and the course of the polymerization after the addition of a sufficient amount of copper oxides to produce antimicrobial properties was not predictable”). Appeal Br. 10. However, Appellant cites no specific support for this statement. “Attorneys’ argument is no substitute for evidence.” Johnston v. IVAC Corp., 885 F.2d 1574, 1581 (Fed. Cir. 1989); Ans. 6. To the extent Appellant relies on the Locke Declaration for these arguments, we are not persuade for the reasons set forth below in our discussion of the Locke Declaration. Appeal 2020-001919 Application 14/420,518 14 argument regarding In re Lindner is “misguided” because it is predicated on a mistaken assumption that the obviousness rejection is based on “a substitution of fillers,” i.e., substitution of copper oxide for the microspheres taught in Fritz).10 Assuming for the sake of argument that the Examiner’s prima facie case depends on replacing/combining Fritz’s microspheres with copper oxide, Appellant is also incorrect that Fritz only teaches “mixing the microspheres (copper oxide) directly with the resin, . . . with the curing agent, or both to form . . . premixes.” Appeal Br. 5. For example, Fritz also teaches pouring microspheres directly over the top of catalyzed resin mixtures (i.e., where curing agent has been added to thermoset resin and mixed), with generally homogeneous mixing such that the material is prepared directly at the point of use. FF7. Because Appellant appears to equate Fritz’s microspheres with copper oxide, this order of combining ingredients would seem to meet Appellant’s requirement that “the filler [be] first mixed with the copper oxide . . . prior to adding the copper oxide to the resin and the catalyst.” Appeal Br. 5; see also Spec. ¶¶ 83 (stating that “it was surprisingly found that when . . . the copper oxide was added as the final ingredient . . . the congealing [of the mixture] was delayed), 85.11 10 We note that the Examiner does not appear to have cited or relied on In re Lindner, 457 F.2d 506 (CCPA 1972) in the Final Action. 11 We note that, while Appellant contends on appeal that in order to avoid undesirably rapid polymerization “copper oxide could not be added to the resin or the curing agent prior to the initiation of the polymerization process,” Appeal Br. 9, the Specification states that “it was surprisingly found that when the catalyst and the copper oxide were mixed together as a last step or when the copper oxide was added as the final ingredient, or when a blend of the copper oxide and filler or when a paste of the copper oxide Appeal 2020-001919 Application 14/420,518 15 More importantly, Fritz teaches that “[t]he order of mixing the resin, curing agent and microspheres to form catalyzed base mixture can be varied depending on application.” FF7. Similarly, Fritz teaches that the amount of curing agent used in its process may depend on a number of factors such as the amount and type of thermoset resin used in the composition, desired cure time, and the thickness of the object being formed. FF6. Fritz further teaches that “the amount of resin, curing agent and microspheres are chosen so that the resulting homogenous mixture will have a suitable viscosity to form a catalyzed base material.” Id. In other words, the prior art teaches that the order of mixing ingredients, the amount/type of thermoset resin, and the amount of curing agent are all parameters that would affect results. Discovering the optimal order of adding ingredients and the amounts of resin and curing agent to be used so that, e.g., suitable viscosity for forming a catalyzed base material is achieved is analogous to the discovery of optimum or workable ranges by routine experimentation, which is not inventive “where the general conditions of a claim are disclosed in the prior art.”12 In re Aller, 220 F.2d 454, 456 (CCPA 1955). We further note that claim 1 does not require any and resin is formed, the congealing was delayed.” Spec. ¶ 83; see also id. ¶ 15 (describing embodiment comprising a first step of “mixing a polymeric resin or a filler with copper oxide until well blended to for a resin-copper oxide mix or filler-copper oxide blend”) (emphasis added). 12 Appellant contends that “Fritz et al. discusses the control of viscosity based upon the proper ratios of components but not based upon the interaction of components” and that “Fritz et al. has only chosen and taught fillers and microspheres that are inert to the reaction.” Appeal Br. 9. We are not persuaded by Appellant’s narrow reading of Fritz: the proper ratio of components is dependent on the interaction of the components. Appeal 2020-001919 Application 14/420,518 16 particular amount of thermoset resins and, as Appellant acknowledges, Fritz teaches that its composite may be formed of thermoset and thermoplastic resin. FF4; Appeal Br. 9 (acknowledging that “Fritz et al. teaches the catalytic curing of combination of thermoset resins and thermoplastic resins”). Appellant has not provided persuasive evidence that the alleged undesirable interaction between copper oxide and curing agent and/or growing portion of the polymer chain would occur regardless of the amounts and types of thermoset resins and/or curing agents used. Appellant additionally contends that “Gabbay only teaches mixing copper oxides with previously prepared thermoplastic polymers” and that “[t]here are no resins . . . or curing agents used in the process of Gabbay since the polymers are already formed.” Appeal Br. 6. Appellant contends that it is not possible to use Gabbay’s process, which adds copper oxide particles to melted polymer to form a slurry, for incorporating solids into thermoset polymers as taught by Fritz. Id. at 6–7. We are not persuaded. As the Examiner points out, claim 1 does not require a particular amount of thermoset resin, and Fritz teaches the use of thermoset and thermoplastic resins. Ans. 5; FF4. Moreover, “[c]laims may be obvious in view of a combination of references, even if the features of one reference cannot be substituted physically into the structure of the other reference.” Orthopedic Equip. Co. v. U.S., 702 F.2d 1005, 1013 (Fed. Cir. 1983). Appellant cites to In re Omeprazole Patent Litigation, 536 F.3d 1361 (Fed. Cir. 2008), in which the Federal Circuit affirmed a district court decision that claims to certain pharmaceutical preparations comprising a omeprazole core, an inert water-soluble subcoating, and an outer enteric coating, were not obvious over prior art describing an omeprazole tablet Appeal 2020-001919 Application 14/420,518 17 with only an enteric coating, despite other references that generally disclose the use of subcoatings in various other pharmaceutical preparations. Appeal Br. 11–12; Omeprazole, 536 F.3d at 1365, 1379–1380. More particularly, Appellant contends that, [i]n the Omeprazole case, in view of the expectations of those of ordinary skill in the art, adding the subcoating would not have been expected to confer any particular desirable property on the final product. Rather, the final product obtained according to the proposed modifications would merely have been expected to have the same functional properties as the prior art product. This is the same as Subject Application wherein the additional step of combining the filler and the copper oxide masterbatch together prior to addition to the resin and the catalyst would cause an additional step for no apparent reason. The Omeprazole case can also be analyzed in view of the discovery of a previously unknown problem by the patentee. If the adverse interaction between active agent and coating had been known, it might well have been obvious to use a subcoating. This again demonstrates the nonobviousness of the claims of the Subject Application. The problem had not been previously known[;] there would have been no reason to incur additional time and expense to add another layer or step, even though the addition would have been technologically possible. This is true because the prior art of record failed to mention any stability problem in Omeprazole or the adverse curing agent reaction in the Subject Application. Appeal Br. 12. We are not persuaded. In this case, a skilled artisan would have had reason to incorporate the copper oxide discussed in Gabbay into Fritz’s product, in order to obtain the advantage of biofilm resistance discussed in Gabbay. Ans. 6. Likewise, unlike in Omeprazole, it would have been obvious to a skilled artisan to vary the order in which ingredients are added, Appeal 2020-001919 Application 14/420,518 18 because Fritz specifically teaches that the order of addition of ingredients may be altered depending on the application. Ans. 6; FF7. Finally, we have considered the Locke Declaration Appellant submitted in support of “the unpredictability of the initiation and subsequent polymerization process.” Appeal Br. 6. However, we are not persuaded that the declaration, when considered together with the evidence of obviousness, shows that a skilled artisan would not have had reason to combine the disclosures of Fritz and Gabbay with a reasonable expectation of success, or that the prior art combination is not enabling with respect to the claimed invention. As an initial matter, the Locke Declaration fails to provide sufficient explanation of the underlying facts and data on which opinions are based. In re Beattie, 974 F.2d 1309, 1313 (Fed. Cir. 1992) (opinion evidence in declarations has little value without factual support). For example, the Locke Declaration states that “polymerization of thermoset resins in the presence of copper oxide particles, filler, and a catalyst for the thermoset resin . . . was initially discovered by EOS impossible to perform with prior art processes” because “[t]he addition of the copper oxide particles in the polymerization batch resulted in an uncontrollably fast polymerization rate of the thermoset resins.” Lock Decl. ¶ 3. However, the declaration does not explain what prior art processes were used by EOS.13 Likewise, the Locke 13 As discussed below, the only specific process discussed in the declaration is “the addition of copper oxide into the polymerization of thermoset resins catalyzed by MEKP,” which accordingly to the declaration “resulted in an uncontrolled rapid polymerization that increased the viscosity of the polymerization batch too rapidly to pour in a mold.” Locke Decl. ¶ 9. However, the Locke Declaration does not describe the ranges of MEKP Appeal 2020-001919 Application 14/420,518 19 Declaration states that “[e]ngineers and scientists of the joint owners of the patent application . . . spent over a year experimenting with different methods to produce the claimed product.” Dec. ¶ 3; see also id. ¶ 4. However, the declaration does not address whether such experimentation was undue or merely involved routine optimization. In addition, the Locke Declaration does not address all of the disclosures in the prior art and, thus, does not persuasively show that the claim are not obvious when considered together with the evidence of obviousness. For example, the Locke Declaration does not acknowledge or address that Fritz teaches using thermoset and thermoplastic resin. Locke Decl. ¶ 5; FF4. Similarly, the Locke Declaration does not address why a skilled artisan would not have found it obvious to optimize the order of adding ingredients in a method suggested by the combination of Fritz and Gabbay, given that Fritz teaches that the order of mixing ingredients can be varied depending on the application. FF7. The Locke Declaration states that “the addition of copper oxide into the polymerization of thermoset resins catalyzed by MEKP resulted in an uncontrolled rapid polymerization that increased the viscosity of the polymerization batch too rapidly to pour in a mold” and that “[i]t was apparent that the copper compounds enhanced the catalytic activity of the catalyst and/or catalyzed the polymerization of the thermoset resins directly.” Locke Decl. ¶¶ 9–10. However, as discussed above, Fritz teaches that the amount of curing agent may be adjusted based on a variety of factors concentration tested. Moreover, Fritz teaches curing agents in addition to MEKP, FF5, and it is not apparent from the declaration whether any curing agents other than MEKP was tested. Appeal 2020-001919 Application 14/420,518 20 such as the identity and amount of the thermoset resin and the desired cure time and that “[t]he amounts of resin, curing agent and microspheres are chosen so that the resulting . . . mixture will have a suitable viscosity to forma catalyzed base material.” FF6. The Locke Declaration does not persuasively address why these disclosures do not render the claims obvious by teaching skilled artisans to optimize the amount of curing agents/catalysts in the method suggested by the combination of Fritz and Gabbay, in order to achieve a suitable viscosity. Likewise, Dr. Locke cites Kochi14 and hypothesizes that rapid polymerization occurs when copper oxide is added directly into the polymerization batch because of “the rapid, exothermic decomposition of organic peroxides in the presence of cuprous bromide or cuprous chloride” and that “premixing the cuprous oxide with the filler prior to addition . . . to the thermoset resin batch results in controllable usable resin handling and subsequent cure” because the filler coats the cuprous oxide, reducing its accessible surface area and shielding the cuprous oxide from interaction with the organic peroxide catalysts such as MEKP. Locke ¶¶ 12–14. Dr. Locke, however, does not address Fritz’s disclosure of curing agents other than organic peroxide catalysts such as MEKP. FF5. Dr. Locke further states that [t]he results and the course of the polymerization after the addition of a sufficient amount of copper oxides to produce antimicrobial properties was not predictable. It was theorized that the copper oxides produced ionic species that interfere, not only with the catalytic initiation of the curing or polymerization but also with the radical, ionic, and/or cationic polymerization 14 Jay K. Kochi, 85 J. AM. CHEM. SOC’Y 1958 (1963). Appeal 2020-001919 Application 14/420,518 21 processes after initiation. The monomers form ionic species when the unsaturated monomers react with the initiator or a growing polymer chain. Whether and the degree to which the reaction rates of the initiators and the reactive thermoset resins were altered and whether the claimed products could be produced under these conditions was unknown. Locke Decl. ¶ 10; see also Appeal Br. 8 (stating that “[t]here is no finite number of predictable solutions with anticipated success to the problem of rapid polymerization and increase in viscosity prior to molding” and that “[t]his is a new problem in the art and no solution provided a certain . . . outcome”). We are not persuaded. The primary, if not the only, basis for Dr. Locke’s opinion in this regard appears to be the work performed by Appellant and the Kochi reference relating to organic peroxides such as MEKP. As discussed above, however, Dr. Locke does not address disclosures in the prior art relating to curing agents other than organic peroxide catalysts.15 As we have discussed above, moreover, “[o]bviousness does not require absolute predictability of success,” only a “reasonable expectation of success.” In re O’Farrell, 853 F.2d 894, 903-04 (Fed. Cir. 1988). Without additional articulation for the basis of Dr. Locke’s opinion, we are not persuaded, based on the conclusory statements in the Locke Declaration, that a skilled artisan would not have a reasonable expectation of 15 Appellant contends in the Appeal Brief that “[c]opper oxide is a reactive ionic species that unpredictably interacts with the radical species produced by the peroxide curing agents or the ionic species produced by the amine curing agents.” See Appeal Br. 7–8; see also id. at 10. Once again, however, Appellant cites no persuasive evidence supporting the contention that copper oxide unpredictably interacts with the ionic species produced by the amine curing agents. Johnston, 885 F.2d at 1581; Ans. 6. Appeal 2020-001919 Application 14/420,518 22 success in combining the teachings of Fritz and Gabbay to produce the composite structural solid material of claim 1, particularly in light of Fritz’s teaching that the order of adding ingredients and amount of curing agents/catalysts used are optimizable result effective variables. FF6, FF7. Neither are we persuaded by the statements in the Locke Declaration that Appellant “are aware of” and/or “understands . . . intimately” the prior art technology, or the statement that neither “the cited references nor any other prior art that [the declarant] knows of provides a method of producing the claimed composite structural solid material and, hence, the claimed composite structural solid material comprising the copper oxide particles was not available prior to the invention of the subject patent application,” Locke Decl. ¶¶ 7–8, 15; see also id. ¶ 11. “An expert opinion is no better than the soundness of the reasons supporting it,” and the conclusory nature of these statements do not entitle them to significant weight. Perreira v. Secretary of the Dept. of HHS, 33 F.3d 1375, 1377 n. 6 (Fed. Cir. 1994). Accordingly, for the reasons discussed above, we affirm the Examiner’s rejection of claim 1 as obvious over Fritz and Gabbay. Appellant asserts that “Claim 50 is directed to the very specific component addition sequence that must be followed in order to prepare the composite structural solid material of Claim 1” and that “[t]his process sequence and process components are not taught by Fritz et al., Gabbay or their combination.” Appeal Br. 9–11. Appellant further contends that “[t]he limitations of Claim 50 that require a specific order of addition of component has not been considered by the examiner.” Id. at 12–13. As the Examiner points out, however, claim 50 is a product-by- process claim. Final Act. 7. “The patentability of a product does not depend Appeal 2020-001919 Application 14/420,518 23 on its method of production. If the product in a product-by-process claim is the same as or obvious from a product of the prior art, the claim is unpatentable even though the prior product was made by a different process.” In re Thorpe, 777 F.2d 695, 697, 227 USPQ 964, 966 (Fed. Cir. 1985). Because we find that the composite structural solid material of claim 1 is obvious over Fritz and Gabbay, we likewise find claim 50 to be obvious over Fritz and Gabbay. Claims 2, 4–9, and 59–62, which are not separately argued, fall with claims 1 and 50. B. Obviousness rejections over Fritz, Gabbay, and Trinder (claims 56 and 58) and over Fritz, Gabbay, and Scher (claim 57) Appellant makes no additional arguments with respect to the obviousness rejections of claims 56 and 58 over Fritz, Gabbay, and Trinder and claim 57 over Fritz, Gabbay, and Scher. Accordingly, we affirm these rejections for the same reasons discussed above with respect to the obviousness rejection over Fritz and Gabbay. C. Indefiniteness rejection (claim 50) The Examiner concludes that [t]he term “substantially” in claim 50 is a relative term which renders the claim indefinite. The term “substantially” is not defined by the claim, the specification does not provide a standard for ascertaining the requisite degree, and one of ordinary skill in the art would not be reasonably apprised of the scope of the invention. Consequently, the claimed polymeric panel or slab is rendered indefinite by the use of the term “substantially”. Final Act. 4. Appeal 2020-001919 Application 14/420,518 24 Appellant does not provide any substantive response to the Examiner’s rejection. We consequently summarily affirm the Examiner’s rejection of claim 50 as indefinite. CONCLUSION In summary: Claim(s) Rejected 35 U.S.C. § Reference(s) / Basis Affirmed Reversed 1, 2, 4–9, 50, 59–62 103(a) Fritz, Gabbay 1, 2, 4–9, 50, 59–62 56, 58 103(a) Fritz, Gabbay, Trinder 56, 58 57 103(a) Fritz, Gabbay, Scher 57 50 112, second paragraph indefiniteness 50 Overall Outcome 1, 2, 4–9, 50, 56–62 TIME PERIOD FOR RESPONSE No time period for taking any subsequent action in connection with this appeal may be extended under 37 C.F.R. § 1.136(a). See 37 C.F.R. § 1.136(a)(1)(iv). AFFIRMED Copy with citationCopy as parenthetical citation