Andreas Heilmann et al.Download PDFPatent Trials and Appeals BoardDec 5, 201912928701 - (D) (P.T.A.B. Dec. 5, 2019) Copy Citation UNITED STATES PATENT AND TRADEMARK OFFICE UNITED STATES DEPARTMENT OF COMMERCE United States Patent and Trademark Office Address: COMMISSIONER FOR PATENTS P.O. Box 1450 Alexandria, Virginia 22313-1450 www.uspto.gov APPLICATION NO. FILING DATE FIRST NAMED INVENTOR ATTORNEY DOCKET NO. CONFIRMATION NO. 12/928,701 12/16/2010 Andreas Heilmann EPPE001 7555 90101 7590 12/05/2019 Friedrich Von Rohrscheidt 7400 Whitepine Road Richmond, VA 23237 EXAMINER PETTITT, JOHN F ART UNIT PAPER NUMBER 3763 NOTIFICATION DATE DELIVERY MODE 12/05/2019 ELECTRONIC Please find below and/or attached an Office communication concerning this application or proceeding. The time period for reply, if any, is set in the attached communication. Notice of the Office communication was sent electronically on above-indicated "Notification Date" to the following e-mail address(es): brendaski3@aol.com fvonrohr@aol.com PTOL-90A (Rev. 04/07) UNITED STATES PATENT AND TRADEMARK OFFICE BEFORE THE PATENT TRIAL AND APPEAL BOARD Ex parte ANDREAS HEILMANN, HEIKO MUELLER, KAI MARSCHNER, and BERT-OLAF GRIMM Appeal 2018-001870 Application 12/928,701 Technology Center 3700 Before ELENI MANTIS MERCADER, LARRY J. HUME, and JUSTIN BUSCH, Administrative Patent Judges. Opinion for the Board filed by Administrative Patent Judge LARRY J. HUME. Opinion Dissenting filed by Administrative Patent Judge JUSTIN BUSCH. HUME, Administrative Patent Judge. DECISION ON APPEAL STATEMENT OF THE CASE Pursuant to 35 U.S.C. § 134(a), Appellant,1 Andreas Heilmann et al., appeal from the Examiner’s decision rejecting claims 1, 3, and 7–14, which are all claims pending in the application. Appellant has canceled claims 2, and 4–6. Br. 5. We have jurisdiction under 35 U.S.C. § 6(b). We REVERSE. 1 We use the word “Appellant” to refer to “applicant” as defined in 37 C.F.R. § 1.42(a). Appellant identifies the real party in interest as Eppendorf AG. Appeal Br. 3. Appeal 2018-001870 Application 12/928,701 2 CLAIMED SUBJECT MATTER2 The claims are directed to a laboratory centrifuge with compressor cooling. See Spec. (Title). In particular, Appellant’s disclosed embodiments and claimed invention “relate[] to a laboratory centrifuge, and more particularly to a laboratory centrifuge including a rotor driven by a centrifuge motor and a cooling device including a compressor, wherein the compressor is a rotation compressor.” Spec. ¶ 2. Claim 1, reproduced below, is representative of the subject matter on appeal (italics added to contested prior-art limitations, and underlining added to contested limitations under § 112, ¶ 2): 1. A centrifuge, comprising: a rotor driven by a centrifuge motor; and a cooling device including a compressor, wherein the centrifuge rotates at speeds between 16,000 RPM and 25,000 RPM, wherein the compressor is a rotating piston compressor, wherein the rotating piston compressor compresses a refrigerant that is in contact with the rotating piston, wherein the centrifuge is configured to reach a remixing rate that is less than or equal to 20% where the remixing rate is equal to (centrifuged value - diffusion value) x 100/100%-value 2 Our decision relies upon Appellant’s Appeal Brief (“Br.,” filed July 9, 2017); Examiner’s Answer (“Ans.,” mailed Oct. 3, 2017); Final Office Action (“Final Act.,” mailed Nov. 17, 2016); and the original Specification (“Spec.,” filed June 27, 2014) (claiming benefit of US 61/284,365, filed Dec. 17, 2009). Appellant did not file a Reply Brief in response to the factual findings and legal conclusions in the Examiner’s Answer. Appeal 2018-001870 Application 12/928,701 3 for a 10 mN Tris-solution and a salt concentrate colorant solution with a density of 1.2 g/ml, and wherein at least one additional rotating piston compressor is disposed in parallel with the rotating piston compressor. 10. A centrifuge, comprising: a rotor driven by a centrifuge motor; and a cooling device including a compressor, wherein the centrifuge rotates at speeds between 16,000 RPM and 25,000 RPM, wherein the compressor is a rotating piston compressor, wherein the rotating piston compressor compresses a refrigerant that is in contact with the rotating piston, and wherein the centrifuge is configured to reach a remixing rate that is less than or equal to 20% where the remixing rate is equal to (centrifuged value - diffusion value) x 100/100%-value for a 10 mN Tris-solution and a salt concentrate colorant solution with a density of 1.2 g/ml. REFERENCES The Examiner relies upon the following prior art as evidence in rejecting the claims on appeal: Rigney US 3,064,449 Nov. 20, 1962 Evans, III et. al. (“Evans”) US 2002/0077239 A1 June 20, 2002 Takahashi et al. (“Takahashi”) US 2008/0132395 A1 June 5, 2008 Yamaguchi et al. (“Yamaguchi”) US 2009/0013714 A1 Jan. 15, 2009 Takamura et. al. (“Takamura”) JP 05228401 A Sept. 7, 1993 Applicant’s Admitted Prior Art, Spec., ¶ 4, hereinafter “AAPA”. Appeal 2018-001870 Application 12/928,701 4 REJECTIONS3 R1. Claims 1, 3, and 7–134 stand rejected under 35 U.S.C. § 112(b) or (pre-AIA) 35 U.S.C. § 112, second paragraph as being indefinite. Final Act. 2; Ans. 2. R2. Claims 1, 3, and 7–14 stand rejected under 35 U.S.C. § 103(a) as being unpatentable over the combination of Takamura, Rigney, and AAPA. Final Act. 8; Ans. 5. R3. Claims 1, 3, and 7–14 stand rejected under 35 U.S.C. § 103(a) as being unpatentable over the combination of Takamura, Yamaguchi, and AAPA. Final Act. 9; Ans. 7. R4. Claims 1, 3, and 7–14 stand rejected under 35 U.S.C. § 103(a) as being unpatentable over the combination of Evans, Rigney, and AAPA. Final Act. 11; Ans. 9. R5. Claims 1, 3, and 7–14 stand rejected under 35 U.S.C. § 103(a) as being unpatentable over the combination of Evans, Yamaguchi, and AAPA. Final Act. 12; Ans. 11. 3 We note the Examiner withdrew several rejections in the Answer. See Ans. 21 (“WITHDRAWN REJECTIONS”). We further note the large number of rejections initially made by the Examiner of claims 1, 3, and 7–14 under 35 U.S.C. § 103(a) in the Final Action, and the lesser, but still relatively large number of prior art rejections restated in the Answer appear to be merely cumulative, and not in accordance with compact examination practice. See generally MPEP §§ 706.02 (“Rejection on Prior Art”) and 2103 (“Patent Examination Process”). 4 We are uncertain as to why claim 14, depending from claim 10, was omitted in the explicit statement of indefiniteness Rejection R1. Appeal 2018-001870 Application 12/928,701 5 R6. Claims 1, 3, and 7–14 stand rejected under 35 U.S.C. § 103(a) as being unpatentable over the combination of Takamura, Rigney, and Takahashi. Ans. 13. R7. Claims 1, 3, and 7–14 stand rejected under 35 U.S.C. § 103(a) as being unpatentable over the combination of Takamura, Yamaguchi, and Takahashi. Ans. 15. R8. Claims 1, 3, and 7–14 stand rejected under 35 U.S.C. § 103(a) as being unpatentable over the combination of Evans, Rigney, and Takahashi. Ans. 18. R9. Claims 1, 3, and 7–14 stand rejected under 35 U.S.C. § 103(a) as being unpatentable over the combination of Evans, Yamaguchi, and Takahashi. Ans. 19. CLAIM GROUPING Based on Appellant’s arguments (Br. 14–66) and our discretion under 37 C.F.R. § 41.37(c)(1)(iv), we decide the appeal of obviousness Rejections R2 through R9 of claims 1, 3, and 7–14 on the basis of representative claim 1. We address separately argued indefiniteness Rejection R1 of claims 1, 3, and 7–13, infra. ISSUES AND ANALYSIS We agree with particular arguments made by Appellant with respect to Rejections R1 through R9 of claims 1, 3, and 7–14. We highlight and address specific findings and arguments regarding claim 1 for emphasis as follows. Appeal 2018-001870 Application 12/928,701 6 For essentially the same reasons argued by Appellant (id.), we reverse the Examiner’s rejection of independent claim 1, and also the rejection of independent claim 10, which recites the disputed limitation in commensurate form. For the same reasons, we also reverse the rejections of all claims that depend therefrom. 1. § 112, ¶ 2, Rejection R1 of Claims 1, 3, and 7–13 Issue 1 Appellant argues (Br. 14–21) the Examiner’s rejection of claims 1, 3, and 7–13 under 35 U.S.C. § 112, second paragraph, as being indefinite is in error. These contentions present us with the following issues: Did the Examiner err (Final Act. 2–3) in determining the following limitations are indefinite? (a) the recitation of “a rotating piston compressor” in independent claims 1 and 10 renders the claims on Appeal indefinite; and (b) the recitations of “the centrifuge is configured to reach a remixing rate is less than or equal to 20%” in claims 1 and 10, or “17%” in claims 7 and 12, or “14%” in claims 8 and 13, and “wherein the remixing rate is equal to (centrifuged value - diffusion value) x 100/100%-value for a 10 mN [sic] Tris-solution and a salt concentrate colorant solution with a density of 1.2 g/ml.” Principles of Law “[A] patent is invalid for indefiniteness if its claims, read in light of the specification delineating the patent, and the prosecution history, fail to inform, with reasonable certainty, those skilled in the art about the scope of Appeal 2018-001870 Application 12/928,701 7 the invention.” Nautilus, Inc. v. Biosig Instruments, Inc., 572 U.S. 898, 901 (2014). Further, we give pending claims “their broadest reasonable interpretation consistent with the specification” and “in light of the specification as it would be interpreted by one of ordinary skill in the art.” Am. Acad., 367 F.3d at 1364. Analysis (a) rotating piston compressor The Examiner concluded: In regard to claims 1, 10, the recitation of “a rotating piston compressor” is indefinite insofar as the applicant maintains that (remarks dated 6/4/2015, page 9, para. 1, and page 7, 3/15/2016) that the prior art does not teach a rotating piston compressor; the broadest reasonable interpretation of “rotating piston compressor” is a compressor having a member that rotates to create compression. The allegations create uncertainty as to what the recitation requires. There is no other definition provided by the applicant and therefore there is no way to discern what the scope of the recitation includes if it does not have the above interpretation and therefore insofar as any other interpretation is used, but is not delineated, such is considered indefinite and indeterminate. Final Act. 2. Appellant argues the phrase “rotating piston compressor” is a well- understood term in the art, and offers extrinsic evidence in the form of website citations, and an indication of a large number of issued patents in which this phrase is allegedly used. See Br. 14–19. On this record, we are persuaded that the term “rotating piston compressor” is sufficiently definite to the extent that a person skilled in the Appeal 2018-001870 Application 12/928,701 8 art would be informed as to the scope of the invention. See Nautilus, 572 U.S. at 901. (b) remixing rate The Examiner determined the “remixing rate” limitations are indefinite first because the functional operation of centrifuging a particular substance such that a certain remixing rate results is not a structure of the centrifuge and there is no way to determine what structure is included and excluded by the functional ability to operate the centrifuge as claimed. Especially as the specification admits that centrifuges with higher speeds of up to 25,000 rpm are able to provide “satisfactory” re-mixing (see spec para. 4). The particular fluids and recited function do nothing to distinguish the structure of the centrifuge other than it operate at high enough speeds to create separation of the claimed substances. This does not further limit the structure of a centrifuge in any definite and discernable way as the claims already recite the speed capability of the centrifuge. Lastly, despite the applicant’s allegations that the prior art is incapable of the remixing rates, it does not appear that a Section 112, first paragraph - new matter or enablement rejection are warranted at present. This is because, it is considered that all that is required to be capable of the remixing limitations is a centrifuge that can operate at 16,000 rpm. However, assuming arguendo that this determination is overcome with evidence that shows that some other structure is required; such a showing would have to be supported by the specification and there does not appear to be any such structure whatsoever other than the ability to operate at the stated speed. Final Act. 3. In response, Appellant argues “[t]here is no doubt one of ordinary skill in the art would be able to determine the scope of the claim. To put it Appeal 2018-001870 Application 12/928,701 9 another way, there is no requirement that every possible structure be spelled out that meets the claim.” Br. 19. Appellant further argues: The claimed remix rate is already a quantitative metric, there is a formula in the specification and the formula is even recited in the claim, and paragraphs [0039] and [0040] detail inventive centrifuges having a remix rate within the claimed amount and prior art centrifuges having a remix rate in excess of the claimed amount. For the foregoing reasons, the rejection of the use of the remix rate in the claims as indefinite under 35 U.S.C. 112(b) or 35 US.C. 112 (pre-AIA), second paragraph should be reversed. Br. 20–21. We are persuaded by Appellant’s argument, and observe that the Examiner appears to have conflated the requirement for written description and/or enablement under 35 U.S.C. § 112, first paragraph, with the requirement for definiteness under § 112, second paragraph. Accordingly, we do not sustain the Examiner’s indefiniteness Rejection R1 of claims 1, 3, and 7–13. 2. § 103 Rejection R2 of Claims 1, 3, and 7–14 Issue 2 Appellant argues (Br. 35–39) the Examiner’s Rejection R2 of claim 1 under 35 U.S.C. § 103(a) as being obvious over the combination of Takamura, Rigney, and AAPA is in error. These contentions present us with the following dispositive issue: Did the Examiner err in finding the cited prior art combination teaches or suggests a centrifuge “configured to reach a remixing rate that is less than or equal to 20% where the remixing rate is equal to (centrifuged value - Appeal 2018-001870 Application 12/928,701 10 diffusion value) x 100/100%-value for a 10 mN Tris-solution and a salt concentrate colorant solution with a density of 1.2 g/ml,” as recited in claim 1? Principles of Law The ultimate issue of obviousness is a matter of law that turns on four underlying factual determinations: (1) the scope and content of the prior art, (2) the level of ordinary skill in the art, (3) the differences between the claimed invention and the prior art, and (4) objective indicia of nonobviousness (secondary considerations). See Graham v. John Deere Co., 383 U.S. 1, 17–18 (1966), as reaffirmed by KSR Int’l Co. v. Teleflex, Inc., 550 U.S. 398, 406 (2007). Analysis Appellant contends: [E]ven if alleged Applicant’s admitted prior art teaches centrifuges operating at 16000 to 25000 RPMs, which Applicant denies, neither Takamura nor Rigney nor the Applicant admitted prior art teach or suggest the remaining features of claim 1 nor claim 10 as follows . . . . “wherein the centrifuge is configured to reach a remixing rate that is less than or equal to 20% where the remixing rate is equal to (centrifuged value – diffusion value) x 100/100%-value,” is not disclosed and is not inherent. Br. 36. We have reviewed the Examiner’s rejection under § 103(a) in both the Final Action and Examiner’s Answer, and do not find any portion of the original rejection or restated rejection in the Answer which addresses this limitation in any manner whatsoever in connection with independent Appeal 2018-001870 Application 12/928,701 11 claim 1, or independent claim 10, which recites the dispositive limitation in commensurate, if not identical, form. 5 Therefore, based upon the findings above, on this record, we are persuaded of at least one error in the Examiner’s reliance on the cited prior art combination to teach or suggest the dispositive limitation of claim 1, such that we find error in the Examiner’s resulting legal conclusion of obviousness. Accordingly, we do not sustain the Examiner’s obviousness Rejection R2 of independent claim 1, and grouped claims 3 and 7–14 which stand therewith. See Claim Grouping, supra. 3. § 103 Rejections R3–R9 of Claims 1, 3, and 7–14 Appellant argues the Examiner’s cumulative Rejections R3 through R9 of claims 1 and 10 under 35 U.S.C. § 103(a) as being obvious over the various combinations of prior art combinations assembled by the Examiner are in error for the same reasons identified above with respect to the dispositive limitation identified in Rejection R2, Issue 2, supra. See, e.g., Br. 40.6 5 Because we agree with at least one of the dispositive arguments advanced by Appellant, we need not reach the merits of Appellant’s other arguments. See Beloit Corp. v. Valmet Oy, 742 F.2d 1421, 1423 (Fed. Cir. 1984) (finding an administrative agency is at liberty to reach a decision based on “a single dispositive issue”). 6 We note an original rejection invoking Takahashi was phrased by the Examiner as “[c]laims 1, 3, 7–14 are rejected under pre-AIA 35 U.S.C. 103(a) as being unpatentable over any of the rejections above and further in view of Takahashi (US 2008/0132395).” Final Act. 12. Although the Examiner restated this original rejection as Rejections R6 through R9 (our labeling) in the Answer, we note Appellant addressed the inadequacy of Appeal 2018-001870 Application 12/928,701 12 Again, we determine that no portion of the original rejections or restated rejections in the Answer address the dispositive limitation in any manner whatsoever in connection with independent claim 1, or independent claim 10, which recites the dispositive limitation in commensurate, if not identical, form. Accordingly, we do not sustain the Examiner’s obviousness Rejections R3 through R9 of claims 1, 3, and 7–14. CONCLUSIONS (1) The Examiner erred with respect to indefiniteness Rejection R1 of claims 1, 3, and 7–13 under 35 U.S.C. § 112, second paragraph, and we do not sustain the rejection. (2) The Examiner erred with respect to obviousness Rejections R2 through R9 of claims 1, 3, and 7–14 under 35 U.S.C. § 103(a) over the cited prior art combinations of record, and we do not sustain the rejections. Takahashi in these rejections (Br. 62–64) by stating, “[t]hus, a remixing rate that is less than or equal to 20% per the claimed invention is neither disclosed nor taught nor inherent in any other prior art referenced in the above rejections nor in Takahashi.” Br. 64. Appeal 2018-001870 Application 12/928,701 13 DECISION SUMMARY Claims Rejected 35 U.S.C. § Basis / References Affirmed Reversed 1, 3, 7–13 112, ¶ 2 Indefiniteness 1, 3, 7–13 1, 3, 7–14 103(a) Obviousness Takamura, Rigney, AAPA 1, 3, 7–14 1, 3, 7–14 103(a) Obviousness Takamura, Yamaguchi, AAPA 1, 3, 7–14 1, 3, 7–14 103(a) Obviousness Evans, Rigney, AAPA 1, 3, 7–14 1, 3, 7–14 103(a) Obviousness Evans, Yamaguchi, AAPA 1, 3, 7–14 1, 3, 7–14 103(a) Obviousness Takamura, Rigney, Takahashi 1, 3, 7–14 1, 3, 7–14 103(a) Obviousness Takamura, Yamaguchi, Takahashi 1, 3, 7–14 1, 3, 7–14 103(a) Obviousness Evans, Rigney, Takahashi 1, 3, 7–14 1, 3, 7–14 103(a) Obviousness Evans, Yamaguchi, Takahashi 1, 3, 7–14 Overall Outcome 1, 3, 7–14 REVERSED Appeal 2018-001870 Application 12/928,701 14 BUSCH, Administrative Patent Judge, dissenting. I respectfully dissent from the Majority’s disposition of the case. Specifically, I disagree with the Majority’s decision reversing the Examiner’s rejection of claims 1, 3, and 7–14 under 35 U.S.C. § 112, second paragraph, as indefinite for failing to particularly point out and distinctly claim the subject matter Appellant regards as the invention. Accordingly, because I would affirm at least one ground of rejection of every pending claim, I would affirm the Examiner’s rejection of claims 1, 3, and 7–14. As the Majority notes, the Examiner rejects claims 1, 3, and 7–14 as indefinite. Final Act. 2–3. Independent claims 1 and 10 recite that “the centrifuge is configured to reach a remixing rate that is less than or equal to 20%.” Br. 68–69. Claims 3, 7–9, and 11–14 depend from, and inherit the limitations of, one of independent claims 1 and 10. The Examiner explains that the limitations relating to the remixing rate the centrifuge is configured to reach are indefinite because the recited resulting remixing rates do not further limit or clearly define the structure required to achieve those remixing rates beyond what is already explicitly recited in independent claims 1 and 10. Final Act. 3 (“the functional operation of centrifuging a particular substance such that a certain remixing rate results is not a structure of the centrifuge and there is no way to determine what structure is included and excluded by the functional ability to operate the centrifuge as claimed”); Ans. 3. The Examiner explains that “[t]he particular fluids and recited function do nothing to distinguish the structure of the centrifuge other than it operate at high enough speeds to create separation of the claimed substances.” Final Act. 3. The Examiner also finds that, other than the already-recited use of particular types of Appeal 2018-001870 Application 12/928,701 15 compressors and rotational speeds, the Specification fails to identify structure that would provide the claimed remixing rates, which leaves a person of ordinary skill in the art without any guidance to determine the structural requirements of the functionally recited limitations, rendering the functional limitations indefinite. Ans. 3–4. The Examiner notes that “any centrifuge capable of the claimed speed range is capable of providing the claimed separation.” Ans. 4. Although Appellant is correct that not every possible structure must be spelled out, see Br. 19, 35 U.S.C. § 112, second paragraph, requires that every claim limitation is definite—i.e., clearly points out the scope of the claimed subject matter. I find Appellant’s other arguments equally unpersuasive. Appellant’s comparison to the claims at issue in In re Barr, 444 F.2d 588 (CCPA 1971) are inapposite because the relevant functional limitation related to a property of the claimed compound. Barr, 444. F.2d 488, 590–92. Similarly, the fact that the claim recites a particular formula for calculating the remix rate does not render the claims definite. Even though a person of ordinary skill in the art could measure remix rates of solutions placed through a centrifuge to determine whether the remix rate satisfies the claimed conditions, that does not provide the person of ordinary skill in the art with a clear and definite understanding of the structure necessary to create that result. Appellant has not persuasively demonstrated that the exact same centrifuge would always produce the same results given the claimed conditions, regardless of the rotational speed (within the claimed range) at which the centrifuge is operated, the amount of time for which the centrifuge is operated, or any other variables that may affect the remix rate. Appeal 2018-001870 Application 12/928,701 16 The resulting remixing rate is, at best, a characteristic of the solution produced by using the claimed centrifuge. In no way does the claimed resulting remixing rate describe or define a characteristic, property, or structure of the claimed centrifuge. Reviewing the Specification provides no further guidance regarding how the claimed resulting remix rate defines or depends on the centrifuge’s structure, other than already recited in the claims.7 See Catalina Mktg. Int’l Inc. v. Coolsavings.com, Inc., 289 F.3d 801, 809 (Fed. Cir. 2002) (the patentability of an apparatus claim “depends on the claimed structure, not on the use or purpose of that structure”). In fact, the Specification implies that the only structure that is important in generating the claimed resulting remix rate is that the compressor is a rotation compressor. Spec. ¶¶ 2, 9, 12, 13 (“vibrations significantly contribute to the high remixing rates”), 14–15 (explaining that compressors having a rotating movement reduces problematic vibrations). The Specification also compares resulting mixing rates generated using a centrifuge having a rolling piston compressor with resulting mixing rates generating using a conventional centrifuge having a reciprocating piston compressor. Spec. ¶¶ 29–41. The Specification notes the components of the 7 Should this matter undergo further prosecution, I also note the Examiner may wish to consider whether the limitation reciting that “the centrifuge rotates at speeds between 16,000 RPM and 25,000 RPM” results in the claim impermissibly mixing an apparatus and a method or if the limitation defines the structure or characteristics of the claimed apparatus. Compare IPXL Holdings, LLC v. Amazon.com, Inc, 430 F.3d 1377, 1384 (Fed. Cir. 2005) (holding a claim term indefinite for covering both an apparatus and a method of using the apparatus), with UltimatePointer, L.L.C. v. Nintendo Co., 816 F.3d 816, 827 (Fed. Cir. 2016) (treating a limitation that “reflects the capability of the structure rather than the activities of the user” as a proper limitation of a claimed apparatus). Appeal 2018-001870 Application 12/928,701 17 two centrifuges, other than the compressors, are the same and the samples were generated using the same variables. Spec. ¶¶ 31–36. Accordingly, the Specification indicates that the different compressor is the structural element of the centrifuge that leads to the claimed resulting remix rates. See Spec. ¶ 41 (“It is apparent from the description provided supra that the laboratory centrifuge 1 according to the invention provides much better de-mixing rates for the centrifuged samples since providing at least one rotation compressor 6 according to the invention introduces much less vibration into the laboratory centrifuge 1 so that much lower mixing rates are achieved.”). For the above reasons, we are left to speculate what further configurations beyond those structural limitations already recited in the claims are necessary to result in “the centrifuge [being] configured to reach a remixing rate that is less than or equal to 20%” (or 17% or 14%). I find the Examiner properly addresses this lack of clarity regarding the scope of the claims by rejecting the claims as indefinite. Therefore, I respectfully disagree with the Majority Opinion that the Examiner’s rejection conflates the requirements of indefiniteness with those of enablement and/or written description. Accordingly, I would conclude that claims 1, 3, and 7–14 are indefinite, and I would affirm the Examiner’s rejection of these claims under 35 U.S.C. § 112, second paragraph. Because the remixing rate limitations are indefinite and do not clearly define the metes and bounds of the claims, determining the necessary structure required by these claims would require speculative assumptions. Therefore, I would reverse all of the Examiner’s rejections because we cannot apply the art without understanding the metes and bounds of the claims. In re Steele, 305 F.2d 859, 862 (CCPA 1962) (a prior art rejection Appeal 2018-001870 Application 12/928,701 18 cannot be sustained if a person of ordinary skill in the art would have to make speculative assumptions concerning the meaning of claim language). 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